Protein Overview: gi|109509450

General Information:
Name(s) found:	gi\|109509450 [NCBI NR]
Description(s) found: Found 2 descriptions. SHOW ALL	gi\|109509450\|ref\|XP_228146.4\| PREDICTED: similar to NAD-dependent deacetylase sirtuin-1 (SIR2alpha) (mSIR2a) (Sir2) (SIR2-like protein 1) [Rattus norvegicus] [NCBI NR]
Organism:	Rattus norvegicus
Length:	637 amino acids
Gene Ontology:
Cellular Component:	nuclear envelope [UNKNOWN] nucleus [UNKNOWN][IDA] PML body [UNKNOWN] [NOT]cytoplasm [UNKNOWN] rDNA heterochromatin [UNKNOWN] nucleolus [UNKNOWN] cellular_component [ND] chromatin silencing complex [UNKNOWN] nucleoplasm [UNKNOWN]
Biological Process:	biological_process [ND] negative regulation of DNA damage response, signal transduction by p53 class mediator [UNKNOWN] spermatogenesis [UNKNOWN] establishment of chromatin silencing [UNKNOWN] maintenance of chromatin silencing [UNKNOWN] protein amino acid deacetylation [UNKNOWN][IDA][IEA] negative regulation of transcription factor activity [UNKNOWN] chromatin silencing [IEA] response to DNA damage stimulus [UNKNOWN] regulation of transcription [IEA] regulation of cell proliferation [UNKNOWN] ovulation from ovarian follicle [UNKNOWN] chromatin silencing at rDNA [UNKNOWN] negative regulation of transcription [UNKNOWN] negative regulation of helicase activity [UNKNOWN] positive regulation of chromatin silencing [UNKNOWN] regulation of protein import into nucleus, translocation [UNKNOWN] peptidyl-lysine deacetylation [UNKNOWN] histone deacetylation [UNKNOWN] response to nutrient levels [IEP] histone H3 deacetylation [IDA]
Molecular Function:	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides [IEA] zinc ion binding [IEA] identical protein binding [UNKNOWN] protein C-terminus binding [UNKNOWN] molecular_function [ND] p53 binding [UNKNOWN] protein binding [UNKNOWN] NAD-dependent protein deacetylase activity [UNKNOWN] histone binding [UNKNOWN] deacetylase activity [UNKNOWN] transcription repressor activity [UNKNOWN] NAD-dependent histone deacetylase activity [UNKNOWN][IDA] NAD binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHKPNRPQST WDCRYGQQAA GDCLSSSFLI SLTDNLLLAD EIITNGFHSC ESDDDDRASH  60
   61 ASSSDWTPRP RIGPYTFVQQ HLMIGTDPRT ILKDLLPETI PPPELDDMTL WQIVINILSE 120
  121 PPKRKKRKDI NTIEDAVKLL QECKKIIVLT GAGVSVSCGI PDFRSRDGIY ARLAVDFPDL 180
  181 PDPQAMFDIE YFRKDPRPFF KFAKEIYPGQ FQPSLCHKFI ALSDKEGKLL RNYTQNIDTL 240
  241 EQVAGIQRII QCHGSFATAS CLICKYKVDC EAVRGDIFNQ VVPRCPRCPA DEPLAIMKPE 300
  301 IVFFGENLPE QFHRAMKYDK DEVDLLIVIG SSLKVRPVAL IPSSIPHEVP QILINREPLP 360
  361 HLHFDVELLG DCDVIINELC HRLGGEYAKL CCNPVKLSEI TEKPPRTQKE LVHLSELPPT 420
  421 PLHISEDSSS PERTVPQDSS VIATLVDQTI KNKVDDLEVS EPKSCVEEKS QEVQTYRNVE 480
  481 SINVENPDFK AVGSSTGDKN ERTSVAETVR KCWPNRLAKE QISKRLDGNQ YLFVPPNRYI 540
  541 FHGAEVYSDS EDDALSSSSC GSNSDSGTCQ SPSLEEPLED ESEIEEFYNG LEDDADRPEC 600
  601 AGGSGADGGD QEAVNEAIAM KQELTDVNCT PDKSEHY

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.98

Protein Overview: gi|109509450

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: