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Protein Overview: DDX50

General Information:
Name(s) found: DDX50 [HGNC (HUGO)]
Description(s) found:
Found 31 descriptions.
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  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 737 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPGKLLWGDI MELEAPLEES ESQKKERQKS DRRKSRHHYD SDEKSETREN GVTDDLDAPK  60
   61 AKKSKMKEKL NGDTEEGFNR LSDEFSKSHK SRRKDLPNGD IDEYEKKSKR VSSLDTSTHK 120
  121 SSDNKLEETL TREQKEGAFS NFPISEETIK LLKGRGVTYL FPIQVKTFGP VYEGKDLIAQ 180
  181 ARTGTGKTFS FAIPLIERLQ RNQETIKKSR SPKVLVLAPT RELANQVAKD FKDITRKLSV 240
  241 ACFYGGTSYQ SQINHIRNGI DILVGTPGRI KDHLQSGRLD LSKLRHVVLD EVDQMLDLGF 300
  301 AEQVEDIIHE SYKTDSEDNP QTLLFSATCP QWVYKVAKKY MKSRYEQVDL VGKMTQKAAT 360
  361 TVEHLAIQCH WSQRPAVIGD VLQVYSGSEG RAIIFCETKK NVTEMAMNPH IKQNAQCLHG 420
  421 DIAQSQREIT LKGFREGSFK VLVATNVAAR GLDIPEVDLV IQSSPPQDVE SYIHRSGRTG 480
  481 RAGRTGICIC FYQPRERGQL RYVEQKAGIT FKRVGVPSTM DLVKSKSMDA IRSLASVSYA 540
  541 AVDFFRPSAQ RLIEEKGAVD ALAAALAHIS GASSFEPRSL ITSDKGFVTM TLESLEEIQD 600
  601 VSCAWKELNR KLSSNAVSQI TRMCLLKGNM GVCFDVPTTE SERLQAEWHD SDWILSVPAK 660
  661 LPEIEEYYDG NTSSNSRQRS GWSSGRSGRS GRSGGRSGGR SGRQSRQGSR SGSRQDGRRR 720
  721 SGNRNRSRSG GHKRSFD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run None Entered Sample pIC145 from april 2005 Okada, M., et al. (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..86] deduced N/A No confident structure predictions are available.
    2 View Details [87..157] PSI-BLAST 72.30103 No description for 2db3A was found.
    3 View Details [158..667] PSI-BLAST 17.221849 Dengue virus RNA helicase
    4 View Details [668..737] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • translation initiation factor activity
    		•  7.79457008386475 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  4.98637553020315 bayes_pls_golite062009
  • translation regulator activity
    		•  4.94658029227343 bayes_pls_golite062009
    		• 4.704140727858 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  4.56509805974548 bayes_pls_golite062009
  • structural molecule activity
    		•  3.58406348799895 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  2.95079405147356 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  2.87427509025394 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  2.85499564954033 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  2.85178667290149 bayes_pls_golite062009
  • motor activity
    		•  2.79327761685782 bayes_pls_golite062009
  • microtubule motor activity
    		•  2.74365461017633 bayes_pls_golite062009
  • binding
    		•  2.64537357529343 bayes_pls_golite062009
  • transporter activity
    		•  2.58140740499725 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.51683451033161 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.39695871109024 bayes_pls_golite062009
  • ATPase activity
    		•  2.39535714892224 bayes_pls_golite062009
  • RNA binding
    		•  2.29590582680214 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  2.18396165590908 bayes_pls_golite062009
  • RNA cap binding
    		•  2.17871969124431 bayes_pls_golite062009
  • DNA binding
    		•  1.94055378599526 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.83584389083042 bayes_pls_golite062009
  • helicase activity
    		•  1.70242731830224 bayes_pls_golite062009
  • hydrolase activity
    		•  1.57549510726226 bayes_pls_golite062009
  • protein-DNA loading ATPase activity
    		•  1.54436515966471 bayes_pls_golite062009
  • DNA clamp loader activity
    		•  1.51134988628578 bayes_pls_golite062009
  • RNA helicase activity
    		•  1.42791449104435 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.40488517180956 bayes_pls_golite062009
  • RNA-dependent ATPase activity
    		•  1.39335733374328 bayes_pls_golite062009
  • ATP-dependent RNA helicase activity
    		•  1.36724390116598 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.29730375126024 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  1.2155186842031 bayes_pls_golite062009
  • purine NTP-dependent helicase activity
    		•  1.19311444180077 bayes_pls_golite062009
  • ATP-dependent helicase activity
    		•  1.19311444180077 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • tubulin binding
    		•  0.979946830272106 bayes_pls_golite062009
  • DNA-directed DNA polymerase activity
    		•  0.971476020912368 bayes_pls_golite062009
  • transcription factor activity
    		•  0.959949409533517 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.929901285538132 bayes_pls_golite062009
  • DNA polymerase activity
    		•  0.928091843881235 bayes_pls_golite062009
  • nucleotide binding
    		•  0.922442819194247 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.920987930180051 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.920926158369519 bayes_pls_golite062009
  • microtubule binding
    		•  0.907162506177187 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.906554174337376 bayes_pls_golite062009
  • actin binding
    		•  0.883285269827407 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.782430219754236 bayes_pls_golite062009
  • mRNA binding
    		•  0.76699944561918 bayes_pls_golite062009
  • DNA helicase activity
    		•  0.72881469450553 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  0.652333406433794 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  0.6071273686445 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.607045223341107 bayes_pls_golite062009
  • ATP-dependent DNA helicase activity
    		•  0.5886142102548 bayes_pls_golite062009
  • GTPase activity
    		•  0.437665353870877 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.434775387083003 bayes_pls_golite062009
  • snRNA binding
    		•  0.418985924846052 bayes_pls_golite062009
  • ATP binding
    		•  0.41092997612902 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.385813421701492 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.377870145186619 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.355466224802969 bayes_pls_golite062009
  • guanyl nucleotide binding
    		•  0.296406132096546 bayes_pls_golite062009
  • GTP binding
    		•  0.295705904888768 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  0.294474570607914 bayes_pls_golite062009
  • guanyl ribonucleotide binding
    		•  0.29028316917561 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  0.282352478532746 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  0.220608508617331 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  0.219533217661421 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  0.219157471322311 bayes_pls_golite062009
  • protein binding
    		•  0.170837278876362 bayes_pls_golite062009
  • microfilament motor activity
    		•  0.10236059675512 bayes_pls_golite062009
  • protein transporter activity
    		•  0.0397092337273124 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.0254369227200564 bayes_pls_golite062009
  • signal sequence binding
    		•  6.53725193420218E-4 bayes_pls_golite062009
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle