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Protein Overview: GPI15

General Information:
Name(s) found: GPI15 / YNL038W [SGD]
Description(s) found:
Found 21 descriptions.
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  • Protein involved in the synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the synthesis of glycosylphosphatidylinositol (GPI) anchors; homologous to the human PIG-H protein [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 229 amino acids

    Gene Ontology:
    Cellular Component: glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex [ISSLink to PubMed article][TASLink to PubMed article]
    Biological Process: GPI anchor biosynthetic process [IMPLink to PubMed article][ISSLink to PubMed article]
    Molecular Function: UDP-glycosyltransferase activity [ICLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MISKEYEFGK TSILNRKKYT LVIDEDKNGN FIRFTVLPVS NRKFKKVKQN GRVEINMGIQ  60
   61 YHQIVLILLL NILFYVICLR SRFLEHINRT FEVTIARSFQ ILIIMGLFAL GTIILVRGPS 120
  121 VETVTIFKES GLQLSRVKGM VIFPQQWNRK FFEQVEFISN ERIIDVVINE GFCRGFRVIF 180
  181 YLAAIVRKSS TLKLLFPSNL PSIDDQRLIY NISRKYLSKQ EKPLSRPKD

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Ho Y, et al. (2002) ADH2 AIM21 BUD20 CIC1 COF1 CPR1 EHD3 GPI15 HHF1, HHF2 HMO1 HTB1 HTB2 HYP2 LSM2 MAM33 MDH1 MGM101 MRPS16 OYE2 RLP24 TEF4 UTP20 YFL006W
    View Details Qiu et al. (2008) ERI1 GPI1 GPI15 GPI19 GPI2 SPT14

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #29 Asynchronous Prep5-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..229] MSA 8.014984 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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