Protein Overview: YPT10

General Information:
Name(s) found:	YPT10 / YBR264C [SGD]
Description(s) found: SHOW ONLY BEST	gi\|88985053\|sp\|P38146.2\|YPT10_YEAST RecName: Full=GTP-binding protein YPT10 [NCBI NR] gi\|37362623\|ref\|NP_009823.2\| GTP binding protein that contains the PEST signal sequence specific for proteolytic enzymes; may be involved in vesicular transport; overexpression leads to accumulation of Golgi-like cisternae with budding vesicles; Ypt10p [S [NCBI NR] GTP-binding protein YPT10 OS=Saccharomyces cerevisiae GN=YPT10 PE=1 SV=2 [Swiss-Prot] YPT10 Ypt protein, is degraded by a proteasome-dependent mechanism [mips] Rab family GTP-binding protein that contains the PEST signal sequence specific for proteolytic enzymes; may be involved in vesicular transport; overexpression leads to accumulation of Golgi-like cisternae with budding vesicles [SGD] Chr II from 738324-737725, reverse complement [yeastorf5.fasta] YPT10 SGDID:S0000468, Chr II from 738326-737727, reverse complement, Verified ORF [yeastflysequest.fasta] YPT10 SGDID:S0000468, Chr II from 738364-737765, reverse complement, Verified ORF [10112005cervSGD.fasta] Ypt10p [Saccharomyces cerevisiae] [nrdb_11152004_Chlamydomonas] YPT10 SGDID:S000000468, Chr II from 738364-737765, reverse complement, Verified ORF, "GTP binding protein that contains the PEST signal sequence specific for proteolytic enzymes; may be involved in vesicular transport; overexpression leads to accumulation [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] GTP binding protein that contains the PEST signal sequence specific for proteolytic enzymes; may be involved in vesicular transport; overexpression leads to accumulation of Golgi-like cisternae with budding vesicles; Ypt10p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] GTP-binding protein YPT10 [nr-271106-contam.fasta] YPT10 SGDID:S000000468, Chr II from 738364-737765, reverse complement, Verified ORF, "GTP binding protein that contains the PEST signal sequence specific for proteolytic enzymes; may be involved in vesicular transport; overexpression leads to accumulation of Golgi-like cisternae with budding vesicles" [yeast-bovrabprots.fasta] [chemostatdb.fasta] GTP-binding protein YPT10 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YPT10 PE=1 SV=2 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] YPT10 SGDID:S000000468, Chr II from 738369-737770, Genome Release 64-1-1, reverse complement, Verified ORF, "Rab family GTP-binding protein that contains the PEST signal sequence specific for proteolytic enzymes; may be involved in vesicular transport; overexpression leads to accumulation of Golgi-like cisternae with budding vesicles" [yeast-030211-contam.fasta] YPT10 SGDID:S000000468, Chr II from 738369-737770, Genome Release 64-2-1, reverse complement, Verified ORF, "Rab family GTP-binding protein; contains the PEST signal sequence specific for proteolytic enzymes; may be involved in vesicular transport; overexpression leads to accumulation of Golgi-like cisternae with budding vesicles" [20141208_orf_trans.fasta] YBR264C SGDID:S000000468, Chr II from 738369-737770, Genome Release 64-1-1, reverse complement, Verified ORF, "Rab family GTP-binding protein that contains the PEST signal sequence specific for proteolytic enzymes; may be involved in vesicular transport; overexpression leads to accumulation of Golgi-like cisternae with budding vesicles" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
Organism:	Saccharomyces cerevisiae
Length:	199 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [IDA]
Biological Process:	Golgi organization [IGI]
Molecular Function:	GTPase activity [ISS] guanyl nucleotide binding [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEATIKVVLL GDSSVGKTSI VTRLKSGKFL AKHAATIGAA FITKTIEVPS NDSSTEKRIH  60
   61 MEIWDTAGQE RYKSLVPMYY RDANIALIVF ELGDVSSLQC AKTWFQDLQD RAQGTQVIIV 120
  121 GNKYDLVCEE HSGEVTIPAE LQGLPYVAVS AKTGYNFDTL NKIIISLVPE SQFKTLSKNN 180
  181 EQGNILEINK KKSGSGCIC

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Krogan NJ, et al. (2006)		YPR137C-A, YAR010C YPT10
View Details	Ho Y, et al. (2002)		GDI1 MRS6 SEC4 STE11 VPS21 YPT1 YPT10 YPT31 YPT32 YPT52 YPT6 YPT7

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	PRE9	YPT10	1	Unpublished Fields Lab Data
View Screen	BDF1	YPT10	1	Unpublished Fields Lab Data
View Screen	UBC7	YPT10	1	Unpublished Fields Lab Data
View Screen	SPC98	YPT10	1	Unpublished Fields Lab Data
View Screen	HRT1	YPT10	1	Unpublished Fields Lab Data
View Screen	YPT10	HSL7	1	Unpublished Fields Lab Data
View Screen	YPT10	YIL170W	1	Unpublished Fields Lab Data
View Screen	YPT10	PHO86	1	Unpublished Fields Lab Data
View Screen	YPT10	YMR007W	1	Unpublished Fields Lab Data
View Screen	YPT10	YTA6	1	Unpublished Fields Lab Data
View Screen	YPT10	YPR172W	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	YPT10	Huh WK, et al. (2003)

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..199]	PSI-BLAST	43.69897	X-ray structure of the small G protein Rab11a in complex with GDP

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.96

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2