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Protein Overview: CUE5

General Information:
Name(s) found: CUE5 / YOR042W [SGD]
Description(s) found:
Found 29 descriptions.
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  • Protein containing a CUE domain that binds ubiquitin, which may facilitate intramolecular monoubiquitination; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 411 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEEKEGIKDS SLLEKSNVPE SINEDISKTT DVDLNSDGKK DNDTSAKDGT PKVEEKVNKS  60
   61 SGIDEDEVVT PAEDAKEEEE EHPPLPARRK SEEEPSKENP ILQELKDAFP NLEEKYIKAV 120
  121 IIASQGVLSP AFNALLFLSD PESGKDIELP TQPVRKNPEA PARRRQTQLE QDELLARQLD 180
  181 EQFNSSHSRR RNRDRATRSM HEQRRRRHNP NEREQHHEDS EEEDSWSQFV EKDLPELTDR 240
  241 AGRSLQDTAN KVSNWISDAY RRNFASGNEQ NDNQHGHQDQ QEWEPEIVDL SQGGKNSRPQ 300
  301 QPERRRFNSF GVQVGDDSLE SHGITLHNED GFEDDEDVPP QLPTRTKSGE STGKVVAETT 360
  361 YIDTPDTETK KKWQPLPPEP LDTTPTKVNA VSRNKKNPDE DEFLINSDDE M

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) CLB1 CUE5 LSB3 RTT10 TRM7 YMR259C YSC84
    View Details Ho Y, et al. (2002) ARO1 CKB2 CUE5 LSB3 UBP15 YFR024C YJL045W YLR422W YME2

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run NSE3 No Comments Hazbun TR, et al. (2003)
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)
    View Run RPA135 No Comments Schneider, DA, et al. (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data CUE5 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..88] deduced N/A No confident structure predictions are available.
    2 View Details [89..159] Pfam 8.677781 CUE domain No confident structure predictions are available.
    3 View Details [160..411] deduced N/A No confident structure predictions are available.
    4 View Details [264..326] deduced N/A No confident structure predictions are available.
    5 View Details [327..411] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle