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Protein Overview: EXO1

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

  BAIT COMMENTS PUBLICATION
View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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  PROTEIN(S) PUBLICATION
View Data EXO1 Huh WK, et al. (2003)

Protein Structure Data


[What does the above image mean?]
[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#   Region(s) Method Confidence Match Description
1 View Details [1..361] PSI-BLAST 188.30103 Flap endonuclease-1 (Fen-1 nuclease)
2 View Details [362..427] PSI-BLAST 3.0 Exonuclease domain of prokaryotic DNA polymerase; DNA polymerase I (Klenow fragment)
3 View Details [428..702] deduced N/A No confident structure predictions are available.

Functions predicted (by domain):

# Gene Ontology predictions
1
Term Confidence Notes
  • hydrolase activity, acting on ester bonds
  • 5.44893156272125 bayes_pls_golite062009
  • single-stranded DNA specific 3'-5' exodeoxyribonuclease activity
  • 4.19173394038227 bayes_pls_golite062009
  • flap endonuclease activity
  • 4.10438637013244 bayes_pls_golite062009
  • exonuclease activity
  • 3.55065728618765 bayes_pls_golite062009
  • endonuclease activity
  • 3.40075034200919 bayes_pls_golite062009
  • endodeoxyribonuclease activity
  • 3.29138075959109 bayes_pls_golite062009
  • deoxyribonuclease activity
  • 3.25110450559975 bayes_pls_golite062009
  • 5'-3' exonuclease activity
  • 3.19536858640519 bayes_pls_golite062009
  • nuclease activity
  • 2.50181033811809 bayes_pls_golite062009
  • hydrolase activity
  • 2.4418166499042 bayes_pls_golite062009
  • exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
  • 2.3324415860722 bayes_pls_golite062009
  • 5'-3' exodeoxyribonuclease activity
  • 2.26658239783943 bayes_pls_golite062009
  • double-stranded DNA specific exodeoxyribonuclease activity
  • 2.09057967200253 bayes_pls_golite062009
  • nucleic acid binding
  • 2.02510018436829 bayes_pls_golite062009
  • exodeoxyribonuclease activity
  • 2.0005433655378 bayes_pls_golite062009
  • exodeoxyribonuclease activity, producing 5'-phosphomonoesters
  • 1.9833086883205 bayes_pls_golite062009
  • DNA binding
  • 1.93844174573408 bayes_pls_golite062009
  • binding
  • 1.86985246794396 bayes_pls_golite062009
  • ribonuclease activity
  • 1.84042322103694 bayes_pls_golite062009
  • 5'-flap endonuclease activity
  • 1.81850767854435 bayes_pls_golite062009
  • single-stranded DNA specific exodeoxyribonuclease activity
  • 1.61167902830399 bayes_pls_golite062009
  • damaged DNA binding
  • 1.42836853175021 bayes_pls_golite062009
  • catalytic activity
  • 1.37534898662234 bayes_pls_golite062009
  • ribonuclease H activity
  • 1.29762010718359 bayes_pls_golite062009
  • structure-specific DNA binding
  • 1.16717206930423 bayes_pls_golite062009
  • single-stranded DNA specific 5'-3' exodeoxyribonuclease activity
  • 1.15948049342759 bayes_pls_golite062009
  • single-stranded DNA specific endodeoxyribonuclease activity
  • 1.10463550341524 bayes_pls_golite062009
  • endodeoxyribonuclease activity, producing 5'-phosphomonoesters
  • 0.901965019685213 bayes_pls_golite062009
  • endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
  • 0.512509234493511 bayes_pls_golite062009
  • protein binding
  • 0.389020243587168 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
  • 0.319622686426271 bayes_pls_golite062009
  • endoribonuclease activity
  • 0.312346277055223 bayes_pls_golite062009
  • DNA polymerase activity
  • 0.250070491623222 bayes_pls_golite062009
  • DNA-directed DNA polymerase activity
  • 0.233683378650593 bayes_pls_golite062009
  • double-stranded DNA binding
  • 0.0978227645302046 bayes_pls_golite062009
  • 3'-5'-exodeoxyribonuclease activity
  • 0.0205129272358 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.




    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)


    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle