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Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid. Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks. Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks. Catalysis of the cleavage of a 3' flap structure in DNA, but not other DNA structures; processes the 3' ends of Okazaki fragments in lagging strand DNA synthesis. Catalysis of the cleavage of a flap structure in DNA, but not other DNA structures; processes the ends of Okazaki fragments in lagging strand DNA synthesis. Catalysis of the cleavage of a 5' flap structure in DNA, but not other DNA structures; processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: flap endonuclease activity
Acc: GO:0048256
Aspect: Molecular Function
Desc: Catalysis of the cleavage of a flap structure in DNA, but not other DNA structures; processes the ends of Okazaki fragments in lagging strand DNA synthesis.
Proteins in PDR annotated with:
   This term: 8 [Search]
   Term or descendants: 24 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0048256 - flap endonuclease activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle