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Catalysis of the reaction: endonucleolytic cleavage to give 5'-phosphooligonucleotide end-products, with a preference for cleavage within the sequence CC. Catalysis of the endonucleolytic cleavage at apurinic or apyrimidinic sites to products with a 5'-phosphate. Catalysis of the endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5' or 3' protrusions; ATP is simultaneously hydrolyzed. Cleavage is dependent on the presence in the DNA of a specific recognition site. Cleavage may occur hundreds or thousands of base pairs away from the recognition site due to translocation of DNA. Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 5'-phosphomonoesters. Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks. Catalysis of the endonucleolytic cleavage to 5'-phosphooligonucleotide end-products. Catalysis of the endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates and 3' hydroxyls. Cleavage is dependent on the presence in the DNA of a specific recognition site; cleavage occurs at or very near this recognition site. Catalysis of the endonucleolytic cleavage of DNA to 5'-phosphodinucleotide and 5'-phosphooligonucleotide end products. Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid. Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks. Catalysis of the endonucleolytic cleavage of DNA to give double-stranded fragments with terminal 5'-phosphates. ATP hydrolysis is required. Cleavage is dependent on the presence of two copies of a specific recognition sequence in an inverse orientation in the DNA. Cleavage occurs at a specific distance from one of the recognition sites. Catalysis of the cleavage of a 5' flap structure in DNA, but not other DNA structures; processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis. Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by creating internal breaks to yield 5'-phosphomonoesters.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: endodeoxyribonuclease activity, producing 5'-phosphomonoesters
Acc: GO:0016888
Aspect: Molecular Function
Desc: Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by creating internal breaks to yield 5'-phosphomonoesters.
Synonyms:
  • endodeoxyribonuclease activity, producing 5' phosphomonoesters
Proteins in PDR annotated with:
   This term: 23 [Search]
   Term or descendants: 58 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0016888 - endodeoxyribonuclease activity, producing 5'-phosphomonoesters (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle