Protein Overview: KTR5

General Information:
Name(s) found:	KTR5 / YNL029C [SGD]
Description(s) found: SHOW ONLY BEST	gi\|6324300\|ref\|NP_014369.1\| Putative mannosyltransferase involved in protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family; Ktr5p [Saccharomyces cerevisiae] [NCBI NR] pir\|\|S62941 probable membrane protein YNL029c - yeast (Saccharomyces cerevisiae) [NCBI NR] gi\|1730718\|sp\|P53966.1\|KTR5_YEAST RecName: Full=Probable mannosyltransferase KTR5 [NCBI NR] gi\|1301865\|emb\|CAA95891.1\| KTR5 [Saccharomyces cerevisiae] [NCBI NR] Probable mannosyltransferase KTR5 OS=Saccharomyces cerevisiae GN=KTR5 PE=1 SV=1 [Swiss-Prot] KTR5 Putative mannosyltransferase [mips] Putative mannosyltransferase involved in protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family [SGD] KTR5, Chr XIV from 577201-578769, reverse complement [yeast_orfs2] Chr XIV from 577201-578769, reverse complement [yeastorf3.fasta] Chr XIV from 578769-577201, reverse complement [yeastorf5.fasta] (P53966) Probable mannosyltransferase KTR5 (EC 2.4.1.131) [4932.FASTACCERV.txt] KTR5 SGDID:S0004974, Chr XIV from 578771-577203, reverse complement, Verified ORF [yeastflysequest.fasta] KTR5 SGDID:S0004974, Chr XIV from 578772-577204, reverse complement, Verified ORF [10112005cervSGD.fasta] Ktr5p [Saccharomyces cerevisiae]gi\|1301865\|emb\|CAA95891.1\| KTR5 [Saccharomyces cerevisiae]gi\|2132735\|pir\|\|S62941 probable membrane protein YNL029c - yeast (Saccharomyces cerevisiae)gi\|1730718\|sp\|P53966\|KTR5_YEAST Probable mannosyltransferase KTR5 [nrdb_11152004_Chlamydomonas] KTR5 SGDID:S000004974, Chr XIV from 578774-577206, reverse complement, Verified ORF, "Putative mannosyltransferase involved in protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] Probable mannosyltransferase KTR5 [nr-271106-contam.fasta] Putative mannosyltransferase involved in protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family; Ktr5p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] KTR5 [Saccharomyces cerevisiae] [nr-271106-contam.fasta] KTR5 SGDID:S000004974, Chr XIV from 578775-577207, reverse complement, Verified ORF, "Putative mannosyltransferase involved in protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family" [SGD_S-cerevisiae_na_01-05-2010_reversed.fasta] [chemostatdb.fasta] Probable mannosyltransferase KTR5 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=KTR5 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] KTR5 SGDID:S000004974, Chr XIV from 578773-577205, Genome Release 64-1-1, reverse complement, Verified ORF, "Putative mannosyltransferase involved in protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family" [yeast-030211-contam.fasta] KTR5 SGDID:S000004974, Chr XIV from 578773-577205, Genome Release 64-2-1, reverse complement, Verified ORF, "Putative mannosyltransferase involved in protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family; KTR5 has a paralog, KTR7, that arose from the whole genome duplication" [20141208_orf_trans.fasta] YNL029C SGDID:S000004974, Chr XIV from 578773-577205, Genome Release 64-1-1, reverse complement, Verified ORF, "Putative mannosyltransferase involved in protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
Organism:	Saccharomyces cerevisiae
Length:	522 amino acids
Gene Ontology:
Cellular Component:	Golgi apparatus [ISS]
Biological Process:	cellular cell wall organization [IMP] protein amino acid N-linked glycosylation [ISS]
Molecular Function:	mannosyltransferase activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLIRRTINA FLGCIHCNLT ATCILIAFVI TMYVVLVSEP ASVDGTMGNF LPFSKMDLAT  60
   61 KRDRPFYSNC VNTQDYLLNP SYIKQNASFV MLTRNGELED VIKTINSIEE HFNQWFHYPY 120
  121 VFLNDQPFEE DFKAKVRDVT VGALVEFGTI DEISWNFPSD VKDTFEFYNA IEDQGDRSIL 180
  181 YGNLESYHKM CRFYSGLFYK HPLVQKYEWY WRLEPDVEFF CDITYDPFLE MLRTNKKYGF 240
  241 TIIIPELYWT VPNLFRHTKS FISQKGVTLG SLWKLFTKDY DIFESDDPEL RDWINYDFQA 300
  301 KAKISEKIAI EQLLKKGDDF QQINDDKEGI MNLIHKARSR KHIVEDKFFN EEYNLCHFWS 360
  361 NFEIARLSVF DNDIYNSFFQ YLEKSGGFWK ERWGDAPVHS IGLSLTLDLD DVHYFRDIGY 420
  421 RHSTIQHCPH NAMGNEEFSY LASDSKFKRK NAAYDEGREF GCGCRCRCPK KKREIEDSMG 480
  481 FCVNIWVNLL NQQRGHERHV EALNGNEMEE HIREDYLRQF GN

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Gavin AC, et al. (2002)		ASC1 ATG9 CLU1 FUN12 GLT1 HCR1 IST2 KTR5 LSG1 NIP1 NOG1 NOP7 PRT1 RIC1 RLI1 RPG1 SPT5 SUA7 SUI1 SUI2 SUI3 SUP45 TIF34 TIF35 TIF5 UTP6 YGL036W

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	CEP3	sample cbf3 from feb 2005	Sandall S, et all (2006)

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	RRB1	KTR5	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..443]	Pfam	262.853872	Glycolipid 2-alpha-mannosyltransferase No confident structure predictions are available.
2	View Details	[444..522]	deduced	N/A	No confident structure predictions are available.

Functions predicted (by domain):

Gene Ontology predictions

Term	Confidence	Notes
alpha-1,2-mannosyltransferase activity	6.0576932895264	bayes_pls_golite062009
mannosyltransferase activity	5.57855076532185	bayes_pls_golite062009
transferase activity, transferring hexosyl groups	4.49413422196176	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	4.37944217610823	bayes_pls_golite062009
UDP-glycosyltransferase activity	4.08451171179562	bayes_pls_golite062009
acetylgalactosaminyltransferase activity	3.4614674054855	bayes_pls_golite062009
transferase activity	3.32517438937547	bayes_pls_golite062009
polypeptide N-acetylgalactosaminyltransferase activity	3.19923094610567	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	2.51696952719873	bayes_pls_golite062009
nucleotidyltransferase activity	2.00651267140641	bayes_pls_golite062009
catalytic activity	1.88676710996045	bayes_pls_golite062009
uridylyltransferase activity	1.27888067902271	bayes_pls_golite062009
binding	1.09657219604879	bayes_pls_golite062009
glucuronosyltransferase activity	0.36353543999278	bayes_pls_golite062009
UDP-galactosyltransferase activity	0.10185872015123	bayes_pls_golite062009
galactosyltransferase activity	0.0931461042017721	bayes_pls_golite062009
acetylglucosaminyltransferase activity	0.0562130308868509	bayes_pls_golite062009
alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity	0.0339369954475406	bayes_pls_golite062009
intramolecular oxidoreductase activity	0.0122078907283503	bayes_pls_golite062009

No functions predicted.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2