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Protein Overview: TRI1

General Information:
Name(s) found: TRI1 / YMR233W [SGD]
Description(s) found:
Found 28 descriptions.
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  • Non-essential sumoylated protein of unknown function with similarity to components of human SWI/SNF complex including SMRD3; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm, nucleus and nucleolus [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 226 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    nucleolus [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADINKYIPM VDAILSVSNP DEISPKRVRK ALQILYSVNL DSQRKLINEL ILERFGDIQE  60
   61 NPRVLIPKND LISRDQELSL RLQKEEERPL RSTRKRKGKS ESKSKRKKKK NDSPDSNSIS 120
  121 VRKVLLSAPL QKFLGSEELP RTQVVKMIWQ YIKEHDLQNP KDRREILCDE KMEPIFGKKM 180
  181 TMFSMNKLLT KHLFNPDEIV KHEEEQKQTP EKEIKLENES LPNLSG

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) HIF1 SAP4 SPT2 TRI1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run HSL7 No Comments McCusker D, et al (2007)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen PET111 TRI1 2 Unpublished Fields Lab Data
    View Screen RAD51 TRI1 2 Uetz P, et al. (2000)
    View Screen SNP1 TRI1 1 Unpublished Fields Lab Data
    View Screen UBI4 TRI1 1 Unpublished Fields Lab Data
    View Screen APC5 TRI1 1 Unpublished Fields Lab Data
    View Screen CNS1 TRI1 1 Unpublished Fields Lab Data
    View Screen YHR122W TRI1 1 Hazbun TR, et al. (2003)

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data TRI1 and NOP56 Huh WK, et al. (2003)
    View Data TRI1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..84] MSA 7.038991 View MSA. No confident structure predictions are available.
    2 View Details [85..226] Pfam 51.017729 SWIB/MDM2 domain No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.63842828741542 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.62775554429027 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.953438255689584 bayes_pls_golite062009
  • histone binding
    		•  0.948950535074526 bayes_pls_golite062009
  • protein binding
    		•  0.529408559970229 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  0.439630834571696 bayes_pls_golite062009
    2
    Term Confidence Notes
  • transcription regulator activity
    		•  4.01592136607858 bayes_pls_golite062009
  • binding
    		•  3.20303599400601 bayes_pls_golite062009
  • basal transcription repressor activity
    		•  2.69162769894095 bayes_pls_golite062009
  • transcription coactivator activity
    		•  2.58234407051051 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.98538788872171 bayes_pls_golite062009
  • transcription activator activity
    		•  1.83085389017135 bayes_pls_golite062009
  • transcription factor binding
    		•  1.73032563380905 bayes_pls_golite062009
  • transcription cofactor activity
    		•  1.60414428986898 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  1.51390743508971 bayes_pls_golite062009
  • protein binding
    		•  1.38134467541454 bayes_pls_golite062009
  • ligase activity
    		•  0.802664465339603 bayes_pls_golite062009
  • structural molecule activity
    		•  0.66106995897056 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.15313128037113 bayes_pls_golite062009
  • catalytic activity
    		•  0.121624777548864 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle