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Protein Overview: SAP4

General Information:
Name(s) found: SAP4 / YGL229C [SGD]
Description(s) found:
Found 26 descriptions.
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  • Protein required for function of the Sit4p protein phosphatase, member of a family of similar proteins that form complexes with Sit4p, including Sap155p, Sap185p, and Sap190p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 818 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [ISSLink to PubMed article]
    mitochondrion [IDALink to PubMed articleLink to PubMed article]
    Biological Process: G1/S transition of mitotic cell cycle [IGILink to PubMed article][IMPLink to PubMed article]
    Molecular Function: protein serine/threonine phosphatase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLWPFGETL SHSGIDSILE EYYLIFRSLE GNETSSTDDK KNEPSMESES EFGTESRDRS  60
   61 DLNQSFIDRI LLETALLDEL NGAANDRLVD FICLGYFYDD RSQQVRHMDY LVDMLMAYLK 120
  121 DIDRTGYRTP FLLENSFHQT GEYEDQDDED PMLYVNIISS IFCSKSAPIV EALVQNTPFL 180
  181 SSLFEVFQFE NIEAENCPIL AVFLKINETL LFEQTSSYLE FFKSQPNIVD KFLYHIEVSP 240
  241 LVEFLIKIML TDQVESPTNI IDFLYHQDLI PKCLNLLENS KYSPGIQNSS GELLKALISI 300
  301 STNFKLDTLW IGPNRLTRQL ASPQYVDQLI NIILFQRGHA MGVAVSIIIE LIRKNNSDYD 360
  361 EVDLLSTTIV DNPPSQRDPV YLGHLLYELT MHMEDFYALL IKLENDDDDD HDTASKALPS 420
  421 VKHHLLENQL HESFRPLGFE RVKITELISE MLHCSNMGLM NSKRGEKIAR TRDKCRDTLD 480
  481 QNSLEKAMKN LNINDNTITS NTLEDKCNNN DSNDSNDNQK QKKNIKKKFH DNELYSTFDT 540
  541 SDDNIDDDDD MSFEIPYVSE TQNLKIRKNP TIGDLFKIKL HDLGFFPKFL QLFLRYPWNN 600
  601 FWHNIVFDII QQIFNGRMDF SYNSFLVYSL FDFKKSTRFI PKPLYGSNQK LPVKDFHIIS 660
  661 DFILQGHKDS FEFYEKEKTN LGYMGQLVLI AEEIAKYSKI YKTDLIAPDI YAFLQDEVWM 720
  721 SYSSDILNET RTMCSIILGG GQFCAESDEN TNQDFLEKAD MSKPAHPSTM DENEIVHEED 780
  781 VKLHDKVAEL IDELGQLTEL DIHDKIKDVI VDHHSDLN

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) HIF1 SAP4 SPT2 TRI1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data SAP4 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..528] MSA 5.02092 View MSA. No confident structure predictions are available.
    2 View Details [529..818] MSA 3.011954 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle