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Protein Overview: RED1

General Information:
Name(s) found: RED1 / YLR263W [SGD]
Description(s) found:
Found 25 descriptions.
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  • Protein component of the axial elements of the synaptonemal complex, involved in chromosome segregation during the first meiotic division; interacts with Hop1p; required for wild-type levels of Mek1p kinase activity [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 827 amino acids

    Gene Ontology:
    Cellular Component: lateral element [IDALink to PubMed article]
    Biological Process: meiotic recombination checkpoint [IMPLink to PubMed article]
    positive regulation of catalytic activity [IDALink to PubMed article]
    synaptonemal complex assembly [IMPLink to PubMed article][IPILink to PubMed article][TASLink to PubMed article]
    Molecular Function: chromatin DNA binding [IDALink to PubMed article][IPILink to PubMed article]
    protein binding [IDALink to PubMed articleLink to PubMed article][IPILink to PubMed articleLink to PubMed article]
    structural molecule activity [IDALink to PubMed article][IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEGLKKKIFG VCLKNDLAQT RNETKGIHYG LMTLETSKQL QEFLHLLVIK REVIQNFELL  60
   61 FHIINVAVKI TDSNLPSDDI WHFILKLRFS SEINIDEDSK VLNYLLETGI AMENPVSWKC 120
  121 LAVISSILSS VPQSKKIITN LIETEHAKKI GQLFDNIQDL QQGNFLVEIL SNCFKKSASN 180
  181 SKKVEKIPQL WQSRSKNKFF FENEFYPFSS KNGSLQTCQF LCNNFMSTLS FTGILRQVSY 240
  241 SGSETLKNLR IFKKKDDENS YFIQCIYNKI YLWLDEKAPL EFERKKIRIT KNLKNKIQIK 300
  301 LRQPFHECVR TTADKTALLF NKTKGFQLEF EDEKLGETFF HNVNNIPKIS EVQNFLVLDY 360
  361 IEEEPENEGE EEEQIGRADE QKEDEEEESL DELSTPMVYP IKSSIPHNHN EKVQLVTPDR 420
  421 SVSIRSDEWD LKSNTEDEEG NVLADLKISS TKETKRQTDY VHIDSEDQSP VVSAQMRKMR 480
  481 RESTKTLEIL RQEFKDKDVQ NKEDQSEQIQ NPFVNTSSLV VGKSCLVNPK EKPNIDQTVV 540
  541 GITELKSNSS IKKRDINILD TIFGQPPSKK QKQFHKKEKK KQQKKLTNFK PIIDVPSQDK 600
  601 RNLRSNAPTK PKSIKVSKLR TDKKVTGEKS SPETAAEKVD DQTVRSNDEQ AMSRATKEKC 660
  661 FPDVNEGKEI TKDDAKVSLE SKKNNETFVD SSVVEKHTPP DKDCNNCNIT DILESTTVID 720
  721 LQSPHGLSAP GQNTFTNKLQ EQIYSSINHF SNELVRKISI INQELNKKIL KELSEKYQKL 780
  781 FSELQDNFQN DTNEMLKFMG EIKDMMNLPE DQLVHAIRTR KFDNNKR

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details (MIPS) Mewes HW, et al. (2004) HOP1 RED1 TOP2 ZIP1 ZIP2
    View Details Ho Y, et al. (2002) RED1 SEC7
    View Details Qiu et al. (2008) HOP1 HOP2 HSK3 KAE1 NDJ1 PCC1 RED1 TOP2 ZIP1 ZIP2

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #13 Mitotic Prep2-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data RED1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..320] 3DJury 2.016 No description for 1be3C_ was found.
    2 View Details [321..409] deduced N/A No confident structure predictions are available.
    3 View Details [410..574] deduced N/A No confident structure predictions are available.
    4 View Details [575..737] MSA 1.099992 View MSA. No confident structure predictions are available.
    5 View Details [738..827] deduced N/A Confident ab initio structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.81809833018345 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.438940591104341 bayes_pls_golite062009
  • protein binding
    		•  0.391512016855874 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle