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Protein Overview: GAL2

General Information:
Name(s) found: GAL2 / YLR081W [SGD]
Description(s) found:
Found 23 descriptions.
SHOW ALL
  • Galactose permease, required for utilization of galactose; also able to transport glucose [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 574 amino acids

    Gene Ontology:
    Cellular Component: plasma membrane [IDALink to PubMed article]
    Biological Process: galactose metabolic process [IMPLink to PubMed article]
    galactose transport [IMPLink to PubMed article]
    Molecular Function: galactose transmembrane transporter activity [IMPLink to PubMed article]
    glucose transmembrane transporter activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAVEENNMPV VSQQPQAGED VISSLSKDSH LSAQSQKYSN DELKAGESGS EGSQSVPIEI  60
   61 PKKPMSEYVT VSLLCLCVAF GGFMFGWDTG TISGFVVQTD FLRRFGMKHK DGTHYLSNVR 120
  121 TGLIVAIFNI GCAFGGIILS KGGDMYGRKK GLSIVVSVYI VGIIIQIASI NKWYQYFIGR 180
  181 IISGLGVGGI AVLCPMLISE IAPKHLRGTL VSCYQLMITA GIFLGYCTNY GTKSYSNSVQ 240
  241 WRVPLGLCFA WSLFMIGALT LVPESPRYLC EVNKVEDAKR SIAKSNKVSP EDPAVQAELD 300
  301 LIMAGIEAEK LAGNASWGEL FSTKTKVFQR LLMGVFVQMF QQLTGNNYFF YYGTVIFKSV 360
  361 GLDDSFETSI VIGVVNFAST FFSLWTVENL GHRKCLLLGA ATMMACMVIY ASVGVTRLYP 420
  421 HGKSQPSSKG AGNCMIVFTC FYIFCYATTW APVAWVITAE SFPLRVKSKC MALASASNWV 480
  481 WGFLIAFFTP FITSAINFYY GYVFMGCLVA MFFYVFFFVP ETKGLSLEEI QELWEEGVLP 540
  541 WKSEGWIPSS RRGNNYDLED LQHDDKPWYK AMLE

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Ho Y, et al. (2002) BZZ1 GAL2 HXT7 LAS17 PEP1 PHO84 RPN1 RPN12 RVS167 SLA1 SQT1 VMA6 YHM2
    View Details Qiu et al. (2008) GAL2 HXT4

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run ZDS1 Sample 2- cpn2 from june 2005 McCusker D, et al (2007)
    View Run ZDS1 Sample 3 - cpn + atp, from june 2005 McCusker D, et al (2007)
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..263]
    [312..523]    		 PSI-BLAST 454.9897 No description for 1ja5A_ was found.
    2 View Details [264..311]
    [524..574]    		 PSI-BLAST 454.9897 No description for 1ja5A_ was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • glycerol transmembrane transporter activity
    		•  7.11654923455995 bayes_pls_golite062009
  • alcohol transmembrane transporter activity
    		•  6.7545566917184 bayes_pls_golite062009
  • polyol transmembrane transporter activity
    		•  6.7545566917184 bayes_pls_golite062009
  • glycerol-3-phosphate transmembrane transporter activity
    		•  5.74077413704789 bayes_pls_golite062009
  • transporter activity
    		•  4.09176719149278 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.59744164024479 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.5865018981083 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  3.54194478414824 bayes_pls_golite062009
  • hexose phosphate transmembrane transporter activity
    		•  3.3746965264994 bayes_pls_golite062009
  • glucose-6-phosphate transmembrane transporter activity
    		•  3.3746965264994 bayes_pls_golite062009
  • sugar:hydrogen symporter activity
    		•  2.99050613058546 bayes_pls_golite062009
  • cation:sugar symporter activity
    		•  2.99050613058546 bayes_pls_golite062009
  • monosaccharide transmembrane transporter activity
    		•  2.63293544825311 bayes_pls_golite062009
  • carbohydrate transmembrane transporter activity
    		•  2.62141276633776 bayes_pls_golite062009
  • sugar transmembrane transporter activity
    		•  2.47557586092261 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  2.21266150105753 bayes_pls_golite062009
  • solute:hydrogen symporter activity
    		•  2.10485633822652 bayes_pls_golite062009
  • binding
    		•  1.89539096965643 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  1.79369588808394 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.59419818573076 bayes_pls_golite062009
  • secondary active transmembrane transporter activity
    		•  1.22264637452409 bayes_pls_golite062009
  • symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • solute:cation symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • sugar binding
    		•  0.285073104957756 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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