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Protein Overview: RBG2

General Information:
Name(s) found: RBG2 / YGR173W [SGD]
Description(s) found:
Found 24 descriptions.
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  • Protein with similarity to mammalian developmentally regulated GTP-binding protein [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 368 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: GTP binding [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGIIDKIKAI EEEMARTQKN KATEHHLGLL KGKLARYRQQ LLADEAGSGG GGGSGFEVAK  60
   61 SGDARVVLIG YPSVGKSSLL GKITTTKSEI AHYAFTTLTS VPGVLKYQGA EIQIVDLPGI 120
  121 IYGASQGKGR GRQVVATART ADLVLMVLDA TKSEHQRASL EKELENVGIR LNKEKPNIYY 180
  181 KKKETGGVKV TFTSPPKTNL TEQAIKMILR DYRIHNAEVL VRDDQCTIDD FIDVINEQHR 240
  241 NYVKCLYVYN KIDAVSLEEV DKLAREPNTV VMSCEMDLGL QDVVEEIWYQ LNLSRVYTKK 300
  301 RGVRPVFDDP LVVRNNSTIG DLCHGIHRDF KDKFKYALVW GSSAKHSPQK CGLNHRIDDE 360
  361 DVVSLFAK

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) GIR2 RBG2
    View Details Krogan NJ, et al. (2006) BUD4 CDC13 CDC15 GIR2 PRS5 RBG2 YIL152W
    View Details Ho Y, et al. (2002) GIR2 MDH1 RBG2

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run MLP2 #32 Asynchronous Prep-No Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #13 Mitotic Prep2-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen GIR2 RBG2 2 Unpublished Fields Lab Data
    View Screen PRP16 RBG2 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data RBG2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..298] PSI-BLAST 30.522879 GTPase Era, N-terminal domain; GTPase Era C-terminal domain
    2 View Details [299..368] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • GTP binding
    		•  3.12773729841136 bayes_pls_golite062009
  • guanyl ribonucleotide binding
    		•  3.11992469401001 bayes_pls_golite062009
  • guanyl nucleotide binding
    		•  3.11160667523268 bayes_pls_golite062009
  • binding
    		•  2.79149251200147 bayes_pls_golite062009
  • ribonucleotide binding
    		•  1.3103969098333 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  1.31038866506213 bayes_pls_golite062009
  • purine nucleotide binding
    		•  1.30205192849426 bayes_pls_golite062009
  • nucleotide binding
    		•  1.28752914655985 bayes_pls_golite062009
    2
    Term Confidence Notes
  • binding
    		•  2.64537357529343 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.09956015274464 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.09345198747025 bayes_pls_golite062009
  • guanyl nucleotide binding
    		•  1.89320355239381 bayes_pls_golite062009
  • guanyl ribonucleotide binding
    		•  1.88721318481223 bayes_pls_golite062009
  • GTP binding
    		•  1.87900088157196 bayes_pls_golite062009
  • DNA binding
    		•  1.87765278833074 bayes_pls_golite062009
  • GTPase activity
    		•  1.23010905798386 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  1.21658213854831 bayes_pls_golite062009
  • ribonucleotide binding
    		•  1.21652144153182 bayes_pls_golite062009
  • purine nucleotide binding
    		•  1.21571071905795 bayes_pls_golite062009
  • nucleotide binding
    		•  1.20347573865566 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • motor activity
    		•  0.926612891775441 bayes_pls_golite062009
  • transcription factor activity
    		•  0.682439846757997 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.498311726132348 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.219555040684154 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.198256709027213 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.197994873032963 bayes_pls_golite062009
  • protein binding
    		•  0.170837278876362 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  0.089234257580272 bayes_pls_golite062009
  • helicase activity
    		•  0.0775311459068899 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle