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Protein Overview: COG7

General Information:
Name(s) found: COG7 / YGL005C [SGD]
Description(s) found:
Found 25 descriptions.
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  • Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 279 amino acids

    Gene Ontology:
    Cellular Component: Golgi transport complex [IPILink to PubMed article]
    mitochondrion [IDALink to PubMed articleLink to PubMed article]
    Biological Process: intra-Golgi vesicle-mediated transport [IGILink to PubMed article][IPILink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVELTITGDD DDILSMFFDE EFVPHAFVDI LLSNALNEDQ IQTQSVSSLL LTRLDFYTKN  60
   61 LTKELESTIW NLDKLSQTLP RTWASSRYHK EAEQNDSSLY STESLKSSKL EYYLDTLASA 120
  121 VRALETGMHN VTEKLSDLDN ENNRNTNVRQ QLQSLMLIKE RIEKVVYYLE QVRTVTNIST 180
  181 VRENNTTSTG TDLSITDFRT SLKALEDTID ESLSSAIDNE AKDETNKDLI GRIDSLSELK 240
  241 CLFKGLDKFF AEYSNFSESI KSKAQSYLST KNIDDGMIS

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) COG1 COG2 COG3 COG4 COG5 COG6 COG7 COG8
    View Details (MIPS) Mewes HW, et al. (2004) CIK1 CIN8 COG1 COG2 COG3 COG4 COG5 COG6 COG7 COG8 KAR3 KIP1 KIP2 KIP3 LIN1
    View Details Krogan NJ, et al. (2006) COG1 COG2 COG3 COG4 COG5 COG6 COG7 COG8
    View Details Gavin AC, et al. (2006) COG1 COG2 COG3 COG4 COG5 COG6 COG7 COG8 IML1
    View Details Qiu et al. (2008) COG1 COG2 COG3 COG4 COG5 COG6 COG7 COG8 KAR3 RUD3 SEC22 SED5 VTI1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data COG7 Huh WK, et al. (2003)
    View Data COG7 and ANP1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..202]
    [243..279]    		 ORFEUS 7.83 Hemolysin E (HlyE, ClyA, SheA)
    2 View Details [203..242] ORFEUS 7.83 Hemolysin E (HlyE, ClyA, SheA)


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle