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Protein Overview: COG1

General Information:
Name(s) found: COG1 / YGL223C [SGD]
Description(s) found:
Found 26 descriptions.
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  • Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 417 amino acids

    Gene Ontology:
    Cellular Component: Golgi transport complex [IPILink to PubMed article]
    Biological Process: intra-Golgi vesicle-mediated transport [IGILink to PubMed article][IPILink to PubMed article]
    retrograde transport, vesicle recycling within Golgi [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDEVLPLFRD SHIPQIKDYQ LELQNDLTKT NEAFQKNLLK NYNKILSLTD SVNDLSLNLK  60
   61 NVDQDFKSLC FNDEKFQLNK LTPLPYQTTT HISPPRDEEK VSIPSQNILV ISNWTISINN 120
  121 FCNRIVTSTT PSRIFDELLL NFHELSLIPV PSKFEALVKD KCCRLQKFLV DSMKTLNLTL 180
  181 LQWVKLYNLL NTEFSSKWDD DLLSIFNESL FETLFNDNVQ ALLISSANSK DHQYHSNQQY 240
  241 KDAIVVDFVN SSTFRDHLIR RTVKEINTHL DTLSTLRAKL KEPETLHKLD IFHDNDTNLN 300
  301 DGTVSPLDDD ALKQYIDTAV FYSKGLTNDT TLQIYQTVQP TIEILQNLEL YKCPQETLTD 360
  361 LRNKLITQLQ EFKTQISSRL PSPLENSTSV VDDFITSYNN HNLLQLVIDQ ITQLRQQ

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) COG1 COG2 COG3 COG4 COG5 COG6 COG7 COG8
    View Details (MIPS) Mewes HW, et al. (2004) COG1 COG2 COG3 COG4 COG5 COG6 COG7 COG8
    View Details Krogan NJ, et al. (2006) COG1 COG2 COG3 COG4 COG5 COG6 COG7 COG8
    View Details Gavin AC, et al. (2006) COG1 COG2 COG3 COG4 COG5 COG6 COG7 COG8 IML1
    View Details Qiu et al. (2008) COG1 COG2 COG3 COG4 COG5 COG6 COG7 COG8

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run BOI1 Sample boi 1 with ha tag from october 2005 McCusker D, et al (2007)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data COG1 and COP1 Huh WK, et al. (2003)
    View Data COG1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..417] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle