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Protein Overview: GNA1

General Information:
Name(s) found: GNA1 / YFL017C [SGD]
Description(s) found:
Found 28 descriptions.
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  • Evolutionarily conserved glucosamine-6-phosphate acetyltransferase required for multiple cell cycle events including passage through START, DNA synthesis, and mitosis; involved in UDP-N-acetylglucosamine synthesis, forms GlcNAc6P from AcCoA [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 159 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: UDP-N-acetylglucosamine biosynthetic process [IDALink to PubMed article][IMPLink to PubMed article]
    Molecular Function: glucosamine 6-phosphate N-acetyltransferase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLPDGFYIR RMEEGDLEQV TETLKVLTTV GTITPESFSK LIKYWNEATV WNDNEDKKIM  60
   61 QYNPMVIVDK RTETVAATGN IIIERKIIHE LGLCGHIEDI AVNSKYQGQG LGKLLIDQLV 120
  121 TIGFDYGCYK IILDCDEKNV KFYEKCGFSN AGVEMQIRK

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) GNA1 NUM1 PRE10 PRE4 PRE6 PRE7 PRE8 PRE9 PUP2 SCL1
    View Details Krogan NJ, et al. (2006) ACK1 CIN8 DCG1 GNA1 MCM6 MLP1 PMD1 PMT4 PRE1 PRE10 PRE2 PRE3 PRE4 PRE5 PRE6 PRE7 PRE8 PRE9 PUP1 PUP2 PUP3 RFT1 SCL1 SGA1 SNQ2 TOS8 UMP1 YCR076C YDR179W-A YJL132W YKR070W YLR211C YLR290C

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen CDC23 GNA1 1 Unpublished Fields Lab Data
    View Screen YPT6 GNA1 1 Unpublished Fields Lab Data
    View Screen NAF1 GNA1 1 Hazbun TR, et al. (2003)

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data GNA1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..159] PSI-BLAST 903.0 Glucosamine-phoshate N-acetyltransferase GNA1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transferase activity
    		•  2.42798083712145 bayes_pls_golite062009
  • glucosamine 6-phosphate N-acetyltransferase activity
    		•  1.9998327970246 bayes_pls_golite062009
  • catalytic activity
    		•  1.97933499002461 bayes_pls_golite062009
  • N-acyltransferase activity
    		•  1.67458301402479 bayes_pls_golite062009
  • N-acetyltransferase activity
    		•  1.48038364316264 bayes_pls_golite062009
  • transferase activity, transferring acyl groups other than amino-acyl groups
    		•  1.47571666298157 bayes_pls_golite062009
  • acyltransferase activity
    		•  1.47230586550141 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  1.42711272311757 bayes_pls_golite062009
  • histone acetyltransferase activity
    		•  0.96927652220298 bayes_pls_golite062009
  • lysine N-acetyltransferase activity
    		•  0.96927652220298 bayes_pls_golite062009
  • acetyltransferase activity
    		•  0.823367673029436 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.707651383188015 bayes_pls_golite062009
  • binding
    		•  0.476482789192409 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.441934451407805 bayes_pls_golite062009
  • transcription factor binding
    		•  0.15500618063483 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle