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View Structure Prediction Details

Protein: GNA1
Organism: Saccharomyces cerevisiae
Length: 159 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GNA1.

Description E-value Query
Range
Subject
Range
gi|14277750, gi|... - gi|14277750|pdb|1I1D|D Chain D, Crystal Structure Of Yeast Gna1 Bound To Coa And Glnac-6p, gi|142777...
3.0E-32 [1..159] [3..161]
gi|7429961 - pir||H70428 conserved hypothetical protein aq_1482 - Aquifex aeolicus
gi|2983873, gi|1... - gi|2983873|gb|AAC07426.1| hypothetical protein aq_1482 [Aquifex aeolicus VF5], gi|15606643|ref|NP_21...
2.0E-23 [6..154] [8..150]
Y1207_METJA, YC0... - (Q58604) Hypothetical acetyltransferase MJ1207 (EC 2.3.1.-), Uncharacterized N-acetyltransferase MJ1...
Y1207_METJA - Uncharacterized N-acetyltransferase MJ1207 OS=Methanocaldococcus jannaschii (strain ATCC 43067 / DSM...
4.0E-23 [6..150] [74..212]
GNA1_CANAX - Glucosamine 6-phosphate N-acetyltransferase OS=Candida albicans GN=GNA1 PE=3 SV=1
6.0E-23 [1..158] [1..148]
SNAT_MESAU - Serotonin N-acetyltransferase OS=Mesocricetus auratus GN=AANAT PE=2 SV=1
1.0E-22 [2..152] [31..177]
SNAT_MOUSE - Serotonin N-acetyltransferase OS=Mus musculus GN=Aanat PE=2 SV=1
3.0E-22 [2..152] [29..175]
SNAT_BOVIN - Serotonin N-acetyltransferase OS=Bos taurus GN=AANAT PE=1 SV=1
2.0E-21 [2..152] [31..177]

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Predicted Domain #1
Region A:
Residues: [1-159]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLPDGFYIR RMEEGDLEQV TETLKVLTTV GTITPESFSK LIKYWNEATV WNDNEDKKIM  60
   61 QYNPMVIVDK RTETVAATGN IIIERKIIHE LGLCGHIEDI AVNSKYQGQG LGKLLIDQLV 120
  121 TIGFDYGCYK IILDCDEKNV KFYEKCGFSN AGVEMQIRK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 903.0
Match: 1i1dA_
Description: Glucosamine-phoshate N-acetyltransferase GNA1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transferase activity 2.42798083712145 bayes_pls_golite062009
glucosamine 6-phosphate N-acetyltransferase activity 1.9998327970246 bayes_pls_golite062009
catalytic activity 1.97933499002461 bayes_pls_golite062009
N-acyltransferase activity 1.67458301402479 bayes_pls_golite062009
N-acetyltransferase activity 1.48038364316264 bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups 1.47571666298157 bayes_pls_golite062009
acyltransferase activity 1.47230586550141 bayes_pls_golite062009
transferase activity, transferring acyl groups 1.42711272311757 bayes_pls_golite062009
histone acetyltransferase activity 0.96927652220298 bayes_pls_golite062009
lysine N-acetyltransferase activity 0.96927652220298 bayes_pls_golite062009
acetyltransferase activity 0.823367673029436 bayes_pls_golite062009
nucleic acid binding 0.707651383188015 bayes_pls_golite062009
binding 0.476482789192409 bayes_pls_golite062009
transcription regulator activity 0.441934451407805 bayes_pls_golite062009
transcription factor binding 0.15500618063483 bayes_pls_golite062009

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