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Protein Overview: DIT2

General Information:
Name(s) found: DIT2 / YDR402C [SGD]
Description(s) found:
Found 28 descriptions.
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  • N-formyltyrosine oxidase, sporulation-specific microsomal enzyme involved in the production of N,N-bisformyl dityrosine required for spore wall maturation, homologous to cytochrome P-450s [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 489 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: ascospore wall assembly [IDALink to PubMed article][IMPLink to PubMed article]
    Molecular Function: oxidoreductase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MELLKLLCLI LFLTLSYVAF AIIVPPLNFP KNIPTIPFYV VFLPVIFPID QTELYDLYIR  60
   61 ESMEKYGAVK FFFGSRWNIL VSRSEYLAQI FKDEDTFAKS GNQKKIPYSA LAAYTGDNVI 120
  121 SAYGAVWRNY RNAVTNGLQH FDDAPIFKNA KILCTLIKNR LLEGQTSIPM GPLSQRMALD 180
  181 NISQVALGFD FGALTHEKNA FHEHLIRIKK QIFHPFFLTF PFLDVLPIPS RKKAFKDVVS 240
  241 FRELLVKRVQ DELVNNYKFE QTTFAASDLI RAHNNEIIDY KQLTDNIVII LVAGHENPQL 300
  301 LFNSSLYLLA KYSNEWQEKL RKEVNGITDP KGLADLPLLN AFLFEVVRMY PPLSTIINRC 360
  361 TTKTCKLGAE IVIPKGVYVG YNNFGTSHDP KTWGTTADDF KPERWGSDIE TIRKNWRMAK 420
  421 NRCAVTGFHG GRRACLGEKL ALTEMRISLA EMLKQFRWSL DPEWEEKLTP AGPLCPLNLK 480
  481 LKFNENIME

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #11 Mitotic Prep1-TiO2 enriched, new search criteria Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..489] PSI-BLAST 171.228787 No description for 2c17A_ was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • arachidonic acid monooxygenase activity
    		•  6.76823710927794 bayes_pls_golite062009
  • fatty acid (omega-1)-hydroxylase activity
    		•  6.3313834755701 bayes_pls_golite062009
  • arachidonic acid epoxygenase activity
    		•  4.80764258881036 bayes_pls_golite062009
  • monooxygenase activity
    		•  4.39701968168633 bayes_pls_golite062009
  • steroid hydroxylase activity
    		•  3.34643016685712 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
    		•  3.24344797738248 bayes_pls_golite062009
  • oxygen binding
    		•  2.77495508953933 bayes_pls_golite062009
  • retinoic acid 4-hydroxylase activity
    		•  2.60901411823382 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
    		•  2.56821164444595 bayes_pls_golite062009
  • oxidoreductase activity
    		•  2.35847923992364 bayes_pls_golite062009
  • arachidonic acid 11,12-epoxygenase activity
    		•  2.0071742914584 bayes_pls_golite062009
  • retinoid binding
    		•  1.91237853759594 bayes_pls_golite062009
  • vitamin D 24-hydroxylase activity
    		•  1.81919676974797 bayes_pls_golite062009
  • isoprenoid binding
    		•  1.78853880472253 bayes_pls_golite062009
  • vitamin D3 25-hydroxylase activity
    		•  1.65825585934141 bayes_pls_golite062009
  • vitamin D 25-hydroxylase activity
    		•  1.65825585934141 bayes_pls_golite062009
  • retinoic acid binding
    		•  1.55035199545719 bayes_pls_golite062009
  • electron carrier activity
    		•  1.48516712188486 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen
    		•  1.48367577297695 bayes_pls_golite062009
  • testosterone 6-beta-hydroxylase activity
    		•  1.4661447981611 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen
    		•  1.20113920678403 bayes_pls_golite062009
  • oxysterol 7-alpha-hydroxylase activity
    		•  1.13877300596184 bayes_pls_golite062009
  • binding
    		•  1.0881336564542 bayes_pls_golite062009
  • 25-hydroxycholecalciferol-24-hydroxylase activity
    		•  1.06487564122685 bayes_pls_golite062009
  • demethylase activity
    		•  1.0502020132476 bayes_pls_golite062009
  • flavonoid 3'-monooxygenase activity
    		•  0.89030345144459 bayes_pls_golite062009
  • ecdysteroid 25-hydroxylase activity
    		•  0.89030345144459 bayes_pls_golite062009
  • catalytic activity
    		•  0.608111453189583 bayes_pls_golite062009
  • steroid 17-alpha-monooxygenase activity
    		•  0.56337818662492 bayes_pls_golite062009
  • sterol 14-demethylase activity
    		•  0.510328098559181 bayes_pls_golite062009
  • 1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity
    		•  0.203772707673481 bayes_pls_golite062009
  • cholesterol monooxygenase (side-chain-cleaving) activity
    		•  0.100883462305119 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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