Protein Overview: ASM4

General Information:
Name(s) found:	ASM4 / YDL088C [SGD]
Description(s) found: Found 24 descriptions. SHOW ALL	Nuclear pore complex subunit, part of a subcomplex also containing Nup53p, Nup170p, and Pse1p [SGD]
Organism:	Saccharomyces cerevisiae
Length:	528 amino acids
Gene Ontology:
Cellular Component:	nuclear pore [IDA]
Biological Process:	mRNA export from nucleus [IMP] rRNA export from nucleus [TAS] nuclear pore organization [TAS] snRNP protein import into nucleus [TAS] mRNA-binding (hnRNP) protein import into nucleus [TAS] snRNA export from nucleus [TAS] NLS-bearing substrate import into nucleus [TAS] protein export from nucleus [TAS] protein import into nucleus, docking [IPI] ribosomal protein import into nucleus [TAS]
Molecular Function:	structural molecule activity [TAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFGIRSGNNN GGFTNLTSQA PQTTQMFQSQ SQLQPQPQPQ PQQQQQHLQF NGSSDASSLR  60
   61 FGNSLSNTVN ANNYSSNIGN NSINNNNIKN GTNNISQHGQ GNNPSWVNNP KKRFTPHTVI 120
  121 RRKTTKQNSS SDINQNDDSS SMNATMRNFS KQNQDSKHNE RNKSAANNDI NSLLSNFNDI 180
  181 PPSVTLQDWQ REDEFGSIPS LTTQFVTDKY TAKKTNRSAY DSKNTPNVFD KDSYVRIANI 240
  241 EQNHLDNNYN TAETNNKVHE TSSKSSSLSA IIVFGYPESI SNELIEHFSH FGHIMEDFQV 300
  301 LRLGRGINPN TFRIFHNHDT GCDENDSTVN KSITLKGRNN ESNNKKYPIF TGESWVKLTY 360
  361 NSPSSALRAL QENGTIFRGS LIGCIPYSKN AVEQLAGCKI DNVDDIGEFN VSMYQNSSTS 420
  421 STSNTPSPPN VIITDGTLLR EDDNTPAGHA GNPTNISSPI VANSPNKRLD VIDGKLPFMQ 480
  481 NAGPNSNIPN LLRNLESKMR QQEAKYRNNE PAGFTHKLSN WLFGWNDL

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Qiu et al. (2008)		ASM4 GLE2 MEX67 NSP1 NUP1 NUP116 NUP120 NUP133 NUP145 NUP157 NUP159 NUP170 NUP188 NUP2 NUP42 NUP49 NUP53 NUP60 NUP82 NUP84 POM152

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	ESF1	No Comments	Hazbun TR, et al. (2003)
View Run	RPA135	No Comments	Schneider, DA, et al. (2006)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	NSE5	ASM4	2	Hazbun TR, et al. (2003)

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	ASM4	Huh WK, et al. (2003)

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..226]	MSA	1.004997	View MSA. No confident structure predictions are available.
2	View Details	[227..425]	MSA	1.004996	View MSA. No confident structure predictions are available.
3	View Details	[426..528]	deduced	N/A	No confident structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2