Protein Overview: CTP1

General Information:
Name(s) found:	CTP1 / YBR291C [SGD]
Description(s) found: SHOW ONLY BEST	gi\|83305810\|sp\|P38152.3\|TXTP_YEAST RecName: Full=Tricarboxylate transport protein; AltName: Full=Citrate transport protein; Short=CTP [NCBI NR] gi\|6319768\|ref\|NP_009850.1\| Mitochondrial inner membrane citrate transporter, member of the mitochondrial carrier family; Ctp1p [Saccharomyces cerevisiae] [NCBI NR] pir\|\|S44554 citrate transport protein - yeast (Saccharomyces cerevisiae) [NCBI NR] gi\|536746\|emb\|CAA85256.1\| CTP1 [Saccharomyces cerevisiae] [NCBI NR] gi\|429137\|emb\|CAA53655.1\| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR] gi\|1587550\|prf\|\|2206494U ORF YBR2039 [NCBI NR] Tricarboxylate transport protein OS=Saccharomyces cerevisiae GN=CTP1 PE=2 SV=3 [Swiss-Prot] CTP1 Mitochondrial citrate transporter - member of the mitochondrial carrier (MCF) family [mips] Mitochondrial inner membrane citrate transporter, member of the mitochondrial carrier family [SGD] CTP1, Chr II from 783630-784529, reverse complement [yeast_orfs2] Chr II from 783630-784529, reverse complement [yeastorf3.fasta] Chr II from 783629-784528, reverse complement [yeastorf4.fasta] Chr II from 784526-783627, reverse complement [yeastorf5.fasta] CTP1 SGDID:S0000495, Chr II from 784530-783631, reverse complement, Verified ORF [yeastflysequest.fasta] CTP1 SGDID:S0000495, Chr II from 784568-783669, reverse complement, Verified ORF [10112005cervSGD.fasta] Ctp1p [Saccharomyces cerevisiae]gi\|429137\|emb\|CAA53655.1\| unnamed protein product [Saccharomyces cerevisiae]gi\|536746\|emb\|CAA85256.1\| CTP1 [Saccharomyces cerevisiae]gi\|626251\|pir\|\|S44554 citrate transport protein - yeast (Saccharomyces cerevisiae)gi\|1 [nrdb_11152004_Chlamydomonas] CTP1 SGDID:S000000495, Chr II from 784568-783669, reverse complement, Verified ORF, "Mitochondrial inner membrane citrate transporter, member of the mitochondrial carrier family" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Tricarboxylate transport protein (Citrate transport protein) (CTP) [nr-271106-contam.fasta] ORF YBR2039 [nr-271106-contam.fasta] CTP1 [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Mitochondrial inner membrane citrate transporter, member of the mitochondrial carrier family; Ctp1p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] [chemostatdb.fasta] Tricarboxylate transport protein OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CTP1 PE=2 SV=3 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] CTP1 SGDID:S000000495, Chr II from 784572-783673, Genome Release 64-1-1, reverse complement, Verified ORF, "Mitochondrial inner membrane citrate transporter, member of the mitochondrial carrier family" [yeast-030211-contam.fasta] CTP1 SGDID:S000000495, Chr II from 784572-783673, Genome Release 64-2-1, reverse complement, Verified ORF, "Mitochondrial inner membrane citrate transporter; member of the mitochondrial carrier family" [20141208_orf_trans.fasta] YBR291C SGDID:S000000495, Chr II from 784572-783673, Genome Release 64-1-1, reverse complement, Verified ORF, "Mitochondrial inner membrane citrate transporter, member of the mitochondrial carrier family" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
Organism:	Saccharomyces cerevisiae
Length:	299 amino acids
Gene Ontology:
Cellular Component:	mitochondrion [IDA] mitochondrial inner membrane [ISS]
Biological Process:	mitochondrial citrate transport [IDA][ISS]
Molecular Function:	tricarboxylate secondary active transmembrane transporter activity [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSKATKSDV DPLHSFLAGS LAGAAEACIT YPFEFAKTRL QLIDKASKAS RNPLVLIYKT  60
   61 AKTQGIGSIY VGCPAFIIGN TAKAGIRFLG FDTIKDMLRD SETGELSGTR GVIAGLGAGL 120
  121 LESVAAVTPF EAIKTALIDD KQSATPKYHN NGRGVVRNYS SLVRDKGFSG LYRGVLPVSM 180
  181 RQAANQAVRL GCYNKIKTLI QDYTDSPKDK PLSSGLTFLV GAFSGIVTVY STMPLDTVKT 240
  241 RMQSLDSTKY SSTMNCFATI FKEEGLKTFW KGATPRLGRL VLSGGIVFTI YEKVLVMLA

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Krogan NJ, et al. (2006)		CTP1 ERV25 FKS1 FTR1 MRH1 OLE1 PEX27 ROG3 RPL10 RPL36B RPL37A RPP1A SEC11 SPC1 SPC2 SPC3 TCM62 TSC13 YNR021W
View Details	Qiu et al. (2008)		CTP1 OAC1 YHM2

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	MLP2	#12 Mitotic Prep1-TiO2 Flowthrough	Keck JM, et al. (2011)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	PML1	CTP1	2	Unpublished Fields Lab Data
View Screen	YLR415C	CTP1	2	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	CTP1	Huh WK, et al. (2003)

Protein Structure Data

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Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..105]	Pfam	22.958607	Mitochondrial carrier protein No confident structure predictions are available.
2	View Details	[106..211]	Pfam	14.958607	Mitochondrial carrier protein No confident structure predictions are available.
3	View Details	[212..299]	Pfam	24.142668	Mitochondrial carrier protein No confident structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2