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Protein Overview: TOS1

General Information:
Name(s) found: TOS1 / YBR162C [SGD]
Description(s) found:
Found 32 descriptions.
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  • Covalently-bound cell wall protein of unknown function; identified as a cell cycle regulated SBF target gene; deletion mutants are highly resistant to treatment with beta-1,3-glucanase; has sequence similarity to YJL171C [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 455 amino acids

    Gene Ontology:
    Cellular Component: fungal-type cell wall [IDALink to PubMed articleLink to PubMed article]
    fungal-type vacuole [IDALink to PubMed article]
    Biological Process: response to drug [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLQKLSMTAL VGLFSSVVSL VNADCTYSGG NYYCAQTDAI IYSNVGLSAT YQDVTNMDES  60
   61 SCACTQADFT ASGSLAPFNE ELSVHFRGPI ELLQFGVYYP NGESNALKKR SEKQSIESCK 120
  121 EGEAVVSRHK HQHKRDVAVE YVQVTSTVYV DSNGQTVTAD STNTVVGPAV PSSYTKDSTV 180
  181 LSSSAQAVET SESQSSISSS KTTSSAAAAS SSSSSSSNTN GDWSRGSYFV PGSTSNCTFM 240
  241 NNQGGTAGSG VWSSCFGNSI SFAASDGVSG AASAQALGDV TIKSGNEFMI FSGEECSGNN 300
  301 GDCGYYREGI PAYHGFGGAD KIFVFEFSMP SDTSGSAYNQ DMPAIWLLNA KIPRTLQYGD 360
  361 ASCSCWKTGC GEMDLFEILT AGSDKLISHI HDGQDGGTQD YFERPTDGTL KAAVIFNSSD 420
  421 KTIHIIEVDE SFDATLSDDV VDQWLSKSGS SAALP

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Gavin AC, et al. (2002) COP1 GLO3 GPT2 ILV1 PGK1 RET2 RET3 SAM1 SCJ1 SEC21 SEC26 SEC27 SEC28 SEH1 TOS1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 his-HA tag on RPA135 Schneider, DA, et al. (2006)
    View Run RPA135 his-HA tag on RPA135 Schneider, DA, et al. (2006)
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run MLP2 #21 Asynchronous Prep2-IMAC Phosphopeptide enrichment A1 Keck JM, et al. (2011)
    View Run MLP2 #31 Asynchronous Prep (Protease cleavage) Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data TOS1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..214] deduced N/A No confident structure predictions are available.
    2 View Details [215..455] MSA 1.004918 View MSA. No confident structure predictions are available.
    3 View Details [299..455] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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