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Protein Overview: ZTA1

General Information:
Name(s) found: ZTA1 / YBR046C [SGD]
Description(s) found:
Found 31 descriptions.
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  • NADPH-dependent quinone reductase, GFP-tagged protein localizes to the cytoplasm and nucleus; has similarity to E. coli quinone oxidoreductase and to human zeta-crystallin [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 334 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKCTIPEQQK VILIDEIGGY DVIKYEDYPV PSISEEELLI KNKYTGVNYI ESYFRKGIYP  60
   61 CEKPYVLGRE ASGTVVAKGK GVTNFEVGDQ VAYISNSTFA QYSKISSQGP VMKLPKGTSD 120
  121 EELKLYAAGL LQVLTALSFT NEAYHVKKGD YVLLFAAAGG VGLILNQLLK MKGAHTIAVA 180
  181 STDEKLKIAK EYGAEYLINA SKEDILRQVL KFTNGKGVDA SFDSVGKDTF EISLAALKRK 240
  241 GVFVSFGNAS GLIPPFSITR LSPKNITLVR PQLYGYIADP EEWKYYSDEF FGLVNSKKLN 300
  301 IKIYKTYPLR DYRTAAADIE SRKTVGKLVL EIPQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CEP3 sample cbf3 from feb 2005 Sandall S, et all (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data ZTA1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..130]
    [302..334]    		 PSI-BLAST 530.156545 Quinone oxidoreductase
    2 View Details [131..301] PSI-BLAST 530.156545 Quinone oxidoreductase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ethanol binding
    		•  3.52197234018599 bayes_pls_golite062009
  • NAD or NADH binding
    		•  3.39892156245282 bayes_pls_golite062009
  • oxidoreductase activity
    		•  3.09625241707629 bayes_pls_golite062009
  • methylglyoxal reductase (NADH-dependent) activity
    		•  3.00190838171391 bayes_pls_golite062009
  • alcohol dehydrogenase (NAD) activity
    		•  2.94416173750168 bayes_pls_golite062009
  • retinol binding
    		•  2.90377414635828 bayes_pls_golite062009
  • alcohol dehydrogenase activity, zinc-dependent
    		•  2.26153457113968 bayes_pls_golite062009
  • NADPH:quinone reductase activity
    		•  2.16668841986245 bayes_pls_golite062009
  • alcohol binding
    		•  2.01620480773869 bayes_pls_golite062009
  • all-trans retinal binding
    		•  1.96535395605564 bayes_pls_golite062009
  • benzaldehyde dehydrogenase activity
    		•  1.81250968237368 bayes_pls_golite062009
  • catalytic activity
    		•  1.79741889688267 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  1.65338499044318 bayes_pls_golite062009
  • DNA binding
    		•  1.61355789916908 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.55390653047158 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.48478425318425 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  1.47309297191111 bayes_pls_golite062009
  • chaperone binding
    		•  1.19079350615542 bayes_pls_golite062009
  • retinol dehydrogenase activity
    		•  1.16811519855038 bayes_pls_golite062009
  • binding
    		•  0.982999356179965 bayes_pls_golite062009
  • transcription factor activity
    		•  0.91090893050278 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  0.905392379451071 bayes_pls_golite062009
  • RNA binding
    		•  0.843556706364142 bayes_pls_golite062009
  • structural molecule activity
    		•  0.75267483298133 bayes_pls_golite062009
  • protein binding
    		•  0.507836099271263 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
    		•  0.44080203587472 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.435382281024944 bayes_pls_golite062009
  • signal transducer activity
    		•  0.435382281024944 bayes_pls_golite062009
  • coenzyme binding
    		•  0.35922330382799 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  0.331998750763528 bayes_pls_golite062009
  • hydrogen ion transmembrane transporter activity
    		•  0.261132005311306 bayes_pls_golite062009
  • receptor activity
    		•  0.219998435023684 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors
    		•  0.216422278300306 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.200409117794759 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  0.166857973838454 bayes_pls_golite062009
  • channel activity
    		•  0.166857973838454 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  0.14195924411997 bayes_pls_golite062009
  • G-protein coupled receptor activity
    		•  0.135469305070471 bayes_pls_golite062009
  • methylenetetrahydrofolate dehydrogenase activity
    		•  0.124826575912808 bayes_pls_golite062009
  • methenyltetrahydrofolate cyclohydrolase activity
    		•  0.118312276550651 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  0.0992243118937675 bayes_pls_golite062009
  • ion channel activity
    		•  0.0487923057681532 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.0361234153211201 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  0.0180992866169776 bayes_pls_golite062009
  • gated channel activity
    		•  0.015794644474568 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.73

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle