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Protein Overview: MAP2

General Information:
Name(s) found: MAP2 / YBL091C [SGD]
Description(s) found:
Found 17 descriptions.
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  • Methionine aminopeptidase, catalyzes the cotranslational removal of N-terminal methionine from nascent polypeptides; function is partially redundant with that of Map1p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 421 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [TASLink to PubMed article]
    Biological Process: proteolysis [IDALink to PubMed article]
    Molecular Function: methionyl aminopeptidase activity [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTDAEIENSP ASDLKELNLE NEGVEQQDQA KADESDPVES KKKKNKKKKK KKSNVKKIEL  60
   61 LFPDGKYPEG AWMDYHQDFN LQRTTVEESR YLKRDLERAE HWNDVRKGAE IHRRVRRAIK 120
  121 DRIVPGMKLM DIADMIENTT RKYTGAENLL AMEDPKSQGI GFPTGLSLNH CAAHFTPNAG 180
  181 DKTVLKYEDV MKVDYGVQVN GNIIDSAFTV SFDPQYDNLL AAVKDATYTG IKEAGIDVRL 240
  241 TDIGEAIQEV MESYEVEING ETYQVKPCRN LCGHSIAPYR IHGGKSVPIV KNGDTTKMEE 300
  301 GEHFAIETFG STGRGYVTAG GEVSHYARSA EDHQVMPTLD SAKNLLKTID RNFGTLPFCR 360
  361 RYLDRLGQEK YLFALNNLVR HGLVQDYPPL NDIPGSYTAQ FEHTILLHAH KKEVVSKGDD 420
  421 Y

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) HKR1 MAP2
    View Details Ho Y, et al. (2002) MAP2 RFC3 RFC5 RNQ1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #14 Mitotic Prep2-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data MAP2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..421] PSI-BLAST 1274.0 Methionine aminopeptidase, insert domain; Methionine aminopeptidase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • peptidase activity
    		•  2.60615909541559 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  2.18503136472662 bayes_pls_golite062009
  • hydrolase activity
    		•  1.43646476372001 bayes_pls_golite062009
  • binding
    		•  1.30837875079167 bayes_pls_golite062009
  • aminopeptidase activity
    		•  0.89399203910285 bayes_pls_golite062009
  • exopeptidase activity
    		•  0.762255574851485 bayes_pls_golite062009
  • metallopeptidase activity
    		•  0.629480947971878 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.478507702690501 bayes_pls_golite062009
  • protein binding
    		•  0.378185804009078 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.151893946259744 bayes_pls_golite062009
  • catalytic activity
    		•  0.148551873544128 bayes_pls_golite062009
  • DNA binding
    		•  0.146627179138465 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle