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Protein Overview: EG12680

General Information:
Name(s) found: fliY / EG12680 [EcoGene]
Description(s) found:
Found 4 descriptions.
SHOW ALL
  • cystine transporter subunit / Cystine-binding protein, periplasmic; part of a L-cysteine/L-cystine shuttle system confering hydrogen peroxide resistance; not required for motility; may regulate FliA (sigma 28) [EcoGene]
    • Organism: Escherichia coli str. K-12 substr. MG1655
    Length: 266 amino acids

    Gene Ontology:
    Cellular Component: outer membrane-bounded periplasmic space [IEA]
    periplasmic space [IEA]
    Biological Process: transport [IEA]
    Molecular Function: transporter activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLAHLGRQA LMGVMAVALV AGMSVKSFAD EGLLNKVKER GTLLVGLEGT YPPFSFQGDD  60
   61 GKLTGFEVEF AQQLAKHLGV EASLKPTKWD GMLASLDSKR IDVVINQVTI SDERKKKYDF 120
  121 STPYTISGIQ ALVKKGNEGT IKTADDLKGK KVGVGLGTNY EEWLRQNVQG VDVRTYDDDP 180
  181 TKYQDLRVGR IDAILVDRLA ALDLVKKTND TLAVTGEAFS RQESGVALRK GNEDLLKAVN 240
  241 DAIAEMQKDG TLQALSEKWF GADVTK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..266] PSI-BLAST 49.69897 Glutamine-binding protein

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ATPase activity, coupled to transmembrane movement of substances
    		•  5.10369591387353 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  5.10318083615538 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  5.10318083615538 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  5.08926597039825 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  5.08835444171664 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  5.0778580713249 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  4.39934929410381 bayes_pls_golite062009
  • transporter activity
    		•  4.36277471796561 bayes_pls_golite062009
  • amine transmembrane transporter activity
    		•  4.06067446901213 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  4.05122336499684 bayes_pls_golite062009
  • ATPase activity
    		•  4.04125376161476 bayes_pls_golite062009
  • organic acid transmembrane transporter activity
    		•  4.00950407295699 bayes_pls_golite062009
  • carboxylic acid transmembrane transporter activity
    		•  4.00681079961203 bayes_pls_golite062009
  • polyamine transmembrane transporter activity
    		•  3.56664180812545 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.47889550245964 bayes_pls_golite062009
  • anion transmembrane-transporting ATPase activity
    		•  3.25040168593981 bayes_pls_golite062009
  • inorganic anion transmembrane transporter activity
    		•  3.16446457499691 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  2.87472545473244 bayes_pls_golite062009
  • polyamine-transporting ATPase activity
    		•  2.84609722276735 bayes_pls_golite062009
  • amino acid binding
    		•  2.79295963421917 bayes_pls_golite062009
  • anion transmembrane transporter activity
    		•  2.77148301796671 bayes_pls_golite062009
  • peptide transporter activity
    		•  2.75577307623285 bayes_pls_golite062009
  • molybdate transmembrane-transporting ATPase activity
    		•  2.58578176144479 bayes_pls_golite062009
  • molybdate ion transmembrane transporter activity
    		•  2.58578176144479 bayes_pls_golite062009
  • amino acid transmembrane transporter activity
    		•  2.47628874886983 bayes_pls_golite062009
  • hydrolase activity
    		•  2.41680852416007 bayes_pls_golite062009
  • amine binding
    		•  2.37157043664258 bayes_pls_golite062009
  • polyamine binding
    		•  2.27573366139794 bayes_pls_golite062009
  • oligopeptide transporter activity
    		•  1.91036692266394 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  1.70693655091183 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  1.70643051049474 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  1.65646853917778 bayes_pls_golite062009
  • amino acid-transporting ATPase activity
    		•  1.65232476690022 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  1.63520066802961 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  1.6341518946909 bayes_pls_golite062009
  • amine-transporting ATPase activity
    		•  1.59812090922796 bayes_pls_golite062009
  • binding
    		•  1.54172013140566 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of ions
    		•  0.99134553005852 bayes_pls_golite062009
  • catalytic activity
    		•  0.674312982669564 bayes_pls_golite062009
  • L-amino acid transmembrane transporter activity
    		•  0.29324308961663 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  0.230402103022499 bayes_pls_golite062009
  • putrescine transmembrane transporter activity
    		•  0.212254208912362 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.119916745111395 bayes_pls_golite062009
  • sulfate transmembrane-transporting ATPase activity
    		•  0.0940079640524907 bayes_pls_golite062009
  • transition metal ion transmembrane transporter activity
    		•  0.00844917716785965 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle