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View Structure Prediction Details

Protein: gi|15236471, gi|...
Organism: Arabidopsis thaliana
Length: 457 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|15236471, gi|....

Description E-value Query
Range
Subject
Range
gi|73952971 - gi|73952971|ref|XP_546168.2| PREDICTED: similar to calcium/calmodulin-dependent protein kinase II ga...
306.0 [0..9] [431..8]

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Predicted Domain #1
Region A:
Residues: [1-300]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDRNQKMDHV IGGKFKLGRK LGSGSFGELY LGINIQTGEE VAVKLEPVKT RHPQLQYESK  60
   61 IYMFLQGGTG VPHLKWFGVE GEYSCMVIDL LGPSLEDLFN YCKRIFSLKS VLMLADQLIC 120
  121 RVEYMHSRGF LHRDIKPDNF LMGLGRRANQ VYIIDYGLAK KYKDLQTQKH IPYRENKNLT 180
  181 GTARYASVNT HLGIEQSRRD DLESLGYVLM YFLRGSLPWQ GLKAGTKKQK YDKISEKKML 240
  241 TSVETLCKSY PSEFTSYFHY CRSLRFEDKP DYSYLRRLFR DLFIREGYQL DYVFDWTISK 300
  301 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 67.522879
Match: 1ckiA
Description: Casein kinase-1, CK1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
phosphotransferase activity, alcohol group as acceptor 5.49988294224815 bayes_pls_golite062009
protein kinase activity 5.4586557943719 bayes_pls_golite062009
kinase activity 5.3287080791198 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 4.96052051118534 bayes_pls_golite062009
protein serine/threonine kinase activity 4.46381887831481 bayes_pls_golite062009
transferase activity 3.97138602499442 bayes_pls_golite062009
binding 2.74863538127007 bayes_pls_golite062009
ATP binding 1.97600611746091 bayes_pls_golite062009
adenyl ribonucleotide binding 1.93596671856664 bayes_pls_golite062009
adenyl nucleotide binding 1.90928021591891 bayes_pls_golite062009
purine ribonucleotide binding 1.65732943334212 bayes_pls_golite062009
ribonucleotide binding 1.65726906484847 bayes_pls_golite062009
purine nucleotide binding 1.63763394711025 bayes_pls_golite062009
nucleotide binding 1.63195828048121 bayes_pls_golite062009
protein tyrosine kinase activity 1.3898059094397 bayes_pls_golite062009
receptor signaling protein serine/threonine kinase activity 1.38496328649031 bayes_pls_golite062009
receptor signaling protein activity 1.27291233344322 bayes_pls_golite062009
protein binding 1.22565748038754 bayes_pls_golite062009
catalytic activity 1.21655087018101 bayes_pls_golite062009
transmembrane receptor activity 0.913893847407112 bayes_pls_golite062009
transmembrane receptor protein kinase activity 0.821371946077904 bayes_pls_golite062009
nucleic acid binding 0.794058505655489 bayes_pls_golite062009
transcription regulator activity 0.775404673285876 bayes_pls_golite062009
receptor activity 0.775180603313375 bayes_pls_golite062009
DNA binding 0.714163549867672 bayes_pls_golite062009
transcription factor activity 0.563262875317016 bayes_pls_golite062009
peptidase activity 0.540289770145252 bayes_pls_golite062009
cyclin-dependent protein kinase activity 0.499492353295369 bayes_pls_golite062009
protein serine/threonine/tyrosine kinase activity 0.48345772948903 bayes_pls_golite062009
transmembrane receptor protein tyrosine kinase activity 0.461392047923247 bayes_pls_golite062009
magnesium ion binding 0.393328812780268 bayes_pls_golite062009
MAP kinase kinase kinase activity 0.37115026509016 bayes_pls_golite062009
MAP kinase kinase activity 0.35402045013148 bayes_pls_golite062009
signal transducer activity 0.270054246024761 bayes_pls_golite062009
molecular transducer activity 0.270054246024761 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 0.265003282584135 bayes_pls_golite062009
MAP kinase activity 0.26024936404169 bayes_pls_golite062009
protein kinase C activity 0.0795689006739899 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [301-457]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YPQIGSSSRP RPTPRPALDP PGPPAERAEK PTVGQDLRGR FTGAIEAFTR RNVSSQGALG  60
   61 DRSRHRSSDD IPSSAKEVHE SRNGSTSKRG VISSTRPGSS AEPSENHSSR LFSSGSRHAT 120
  121 TQRVPQSYES AAAARPGHED AIRNFELLTI GSGKKRK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle