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View Structure Prediction Details

Protein: fft3 (reserved)
Organism: Schizosaccharomyces pombe
Length: 922 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for fft3 (reserved).

Description E-value Query
Range
Subject
Range
gi|74181165 - gi|74181165|dbj|BAE27845.1| unnamed protein product [Mus musculus]
408.0 [0..83] [922..423]
fft2 - fun thirty related protein Fft2
FFT2_SCHPO - ATP-dependent helicase fft2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=fft2 PE=1 SV=1
401.0 [0..117] [918..268]
gi|109472135 - gi|109472135|ref|XP_231860.4| PREDICTED: similar to SWI/SNF-related, matrix associated, actin-depend...
400.0 [0..7] [922..371]
gi|73946679 - gi|73946679|ref|XP_860926.1| PREDICTED: similar to SWI/SNF-related matrix-associated actin-dependent...
396.0 [0..83] [922..436]
SMARCA2 - SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
395.0 [0..83] [922..408]

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Predicted Domain #1
Region A:
Residues: [1-176]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDGKRKIEHT ADGTHYDATS NVKRKPIFPP FIADSLSEAT EKANVMGGGM NSRLQILSEM  60
   61 SKRVQATAPI SSLEHFKQLS DISPSFTSSA NSINQPYNYS GSLENLVPTP SAGTPSQFMD 120
  121 AQNPYGAVYN ALSQFSETEP KMPSYMDDEE ASDSLPLSLS SQSLSSQVTN QKPAPH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [177-347]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RLTMRERYAA NNLTNGLQFT LPLSSRKTYE PEADDDSNDD MYSDDDSNAD RWASRIDTAA  60
   61 LKEEVLKYMN RCSTQDLADM TGCTLAEAEF MVAKRPFPDL ESALVVKQPR PVIPKGRRGR 120
  121 REKTPLGPRL VGICMEIMRG YFVVDALIRQ CEQLGGKIQR GIEAWGLSNT A

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.68
Match: 1s5lU
Description: Architecture of the photosynthetic oxygen evolving center
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [348-922]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TSDEGETSLV NFDQMKSFGT PANSSFITTP PASFSPDIKL QDYQIIGINW LYLLYELKLA  60
   61 GILADEMGLG KTCQTIAFFS LLMDKNINGP HLVIAPASTM ENWLREFAKF CPKLKIELYY 120
  121 GSQVEREEIR ERINSNKDSY NVMLTTYRLA ATSKADRLFL RNQKFNVCVY DEGHYLKNRA 180
  181 SERYRHLMSI PADFRVLLTG TPLQNNLKEL ISLLAFILPH VFDYGLKSLD VIFTMKKSPE 240
  241 SDFERALLSE QRVSRAKMMM APFVLRRKKS QVLDALPKKT RIIEFCEFSE EERRRYDDFA 300
  301 SKQSVNSLLD ENVMKTNLDT NANLAKKKST AGFVLVQLRK LADHPMLFRI HYKDDILRQM 360
  361 AKAIMNEPQY KKANELYIFE DMQYMSDIEL HNLCCKFPSI NSFQLKDEPW MDATKVRKLK 420
  421 KLLTNAVENG DRVVLFSQFT QVLDILQLVM KSLNLKFLRF DGSTQVDFRQ DLIDQFYADE 480
  481 SINVFLLSTK AGGFGINLAC ANMVILYDVS FNPFDDLQAE DRAHRVGQKK EVTVYKFVVK 540
  541 DTIEEHIQRL ANAKIALDAT LSGNAETVEA EDDDD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 77.09691
Match: 1z3iX
Description: Structure of the SWI2/SNF2 chromatin remodeling domain of eukaryotic Rad54
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
DNA-dependent ATPase activity 2.72462789867829 bayes_pls_golite062009
nucleoside-triphosphatase activity 2.69246499202248 bayes_pls_golite062009
binding 2.64537357529343 bayes_pls_golite062009
pyrophosphatase activity 2.61582393123755 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 2.59641929642359 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 2.59333672868803 bayes_pls_golite062009
DNA helicase activity 2.2817164193758 bayes_pls_golite062009
transporter activity 2.17383908004663 bayes_pls_golite062009
nucleic acid binding 2.11222585187695 bayes_pls_golite062009
ATPase activity 2.11122403732968 bayes_pls_golite062009
transmembrane transporter activity 2.02444700826552 bayes_pls_golite062009
ATPase activity, coupled 1.8908019270286 bayes_pls_golite062009
ATP-dependent DNA helicase activity 1.88455339138556 bayes_pls_golite062009
DNA binding 1.7904783386531 bayes_pls_golite062009
helicase activity 1.70242731830224 bayes_pls_golite062009
transcription regulator activity 1.68903321260301 bayes_pls_golite062009
microtubule motor activity 1.6537049553461 bayes_pls_golite062009
guanyl nucleotide binding 1.62578154021163 bayes_pls_golite062009
guanyl ribonucleotide binding 1.61568379110546 bayes_pls_golite062009
GTP binding 1.60042477805119 bayes_pls_golite062009
structural constituent of ribosome 1.47858140861683 bayes_pls_golite062009
hydrolase activity 1.35268825531078 bayes_pls_golite062009
motor activity 1.34881124154297 bayes_pls_golite062009
protein-DNA loading ATPase activity 1.29640539057136 bayes_pls_golite062009
structure-specific DNA binding 1.2539059700735 bayes_pls_golite062009
protein binding 1.22129154759482 bayes_pls_golite062009
purine NTP-dependent helicase activity 1.19311444180077 bayes_pls_golite062009
ATP-dependent helicase activity 1.19311444180077 bayes_pls_golite062009
DNA clamp loader activity 1.12431517057397 bayes_pls_golite062009
double-stranded DNA binding 1.117585097627 bayes_pls_golite062009
lysine N-acetyltransferase activity 1.05990253628867 bayes_pls_golite062009
histone acetyltransferase activity 1.05990253628867 bayes_pls_golite062009
catalytic activity 1.00104173493322 bayes_pls_golite062009
substrate-specific transporter activity 0.97700154207756 bayes_pls_golite062009
GTPase activity 0.897989893461858 bayes_pls_golite062009
structural molecule activity 0.86514677273731 bayes_pls_golite062009
purine nucleotide binding 0.725611289205392 bayes_pls_golite062009
nucleotide binding 0.717697610309727 bayes_pls_golite062009
purine ribonucleotide binding 0.713814218071151 bayes_pls_golite062009
ribonucleotide binding 0.713752628021599 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.608058786636536 bayes_pls_golite062009
transcription factor activity 0.603758349693077 bayes_pls_golite062009
single-stranded DNA binding 0.568457189190858 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.539479261019683 bayes_pls_golite062009
cytoskeletal protein binding 0.500462538667228 bayes_pls_golite062009
translation regulator activity 0.493216082928152 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.480200274620277 bayes_pls_golite062009
RNA helicase activity 0.34746349346164 bayes_pls_golite062009
mismatched DNA binding 0.31144582840038 bayes_pls_golite062009
ATP-dependent RNA helicase activity 0.30832907234141 bayes_pls_golite062009
RNA-dependent ATPase activity 0.29532978396745 bayes_pls_golite062009
four-way junction helicase activity 0.26252931460003 bayes_pls_golite062009
ATP binding 0.19169045543599 bayes_pls_golite062009
exodeoxyribonuclease V activity 0.185603938981231 bayes_pls_golite062009
adenyl ribonucleotide binding 0.165732470448462 bayes_pls_golite062009
adenyl nucleotide binding 0.162060759063149 bayes_pls_golite062009
active transmembrane transporter activity 0.114463153989353 bayes_pls_golite062009
microfilament motor activity 0.10236059675512 bayes_pls_golite062009
ion transmembrane transporter activity 0.081265446432119 bayes_pls_golite062009
3'-5' DNA helicase activity 0.0769112340058804 bayes_pls_golite062009
protein transporter activity 0.0397092337273124 bayes_pls_golite062009
actin binding 0.00482938540552702 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle