| Protein: | sck1 |
| Organism: | Schizosaccharomyces pombe |
| Length: | 696 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for sck1.
| Description | E-value | Query Range |
Subject Range |
|
|
531.0 | [0..1] | [696..1] |
|
|
388.0 | [0..1] | [636..21] |
|
|
387.0 | [0..3] | [695..7] |
|
|
386.0 | [0..6] | [643..10] |
|
|
385.0 | [0..26] | [693..203] |
|
|
382.0 | [0..82] | [653..2] |
|
|
379.0 | [0..2] | [642..161] |
|
|
375.0 | [0..37] | [642..38] |
|
Region A: Residues: [1-125] |
1 11 21 31 41 51
| | | | | |
1 MTEIFGKLHR SSNSENTNQA SPSTIQSHST QPVLSNDHST KVNDYEGKEG ASSNGYDPVF 60
61 MSDRMKMRYN EITAQLHKEQ SLKEDKESGS NSSESNGITP MGTYSEKPKL LQSRTPPSSC 120
121 YIRHD
|
| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [126-296] |
1 11 21 31 41 51
| | | | | |
1 TVVPKDKNGQ HAFGRLYVRL HQGRDLNVKS VNAQPYAVIT FEKTQVMVPP PFKDIDGGIP 60
61 ISIPSKNRPL AGSASGSSSG LHSELMLADV RCPHWDFETV FDVTKMKSQM VVSVYDKYED 120
121 DKFLGSVKIT PIFLHEYVQE AWYKLEPLDL TKSLEGEIKV ETIYEHIEHV R
|
| Detection Method: | |
| Confidence: | 5.91 |
| Match: | 2ep6A |
| Description: | No description for 2ep6A was found. |
|
Region A: Residues: [297-566] |
1 11 21 31 41 51
| | | | | |
1 YGPEDFTALR LIGKGTFGQV YLVRKNDTNR IYAMKKISKK LIVRKKEVTH TLGERNILVR 60
61 TSLDESPFIV GLKFSFQTAS DLYLITDYMS GGELFWHLQH EGRFPEQRAK FYIAELVLAL 120
121 EHLHKHDIIY RDLKPENILL DADGHIALCD FGLSKANLSA NATTNTFCGT TEYLAPEVLL 180
181 EDKGYTKQVD FWSLGVLVFE MCCGWSPFYA PDVQQMYRNI AFGKVRFPKG VLSSEGRSFV 240
241 RGLLNRNPNH RLGAVADTTE LKEHPFFADI
|
| Detection Method: | |
| Confidence: | 70.045757 |
| Match: | 1h1wA |
| Description: | 3-phosphoinositide dependent protein kinase-1 Pdk1 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| phosphotransferase activity, alcohol group as acceptor | 5.49988294224815 | bayes_pls_golite062009 |
| protein kinase activity | 5.4586557943719 | bayes_pls_golite062009 |
| kinase activity | 5.3287080791198 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 4.96052051118534 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 4.46381887831481 | bayes_pls_golite062009 |
| calmodulin-dependent protein kinase activity | 4.31938467136214 | bayes_pls_golite062009 |
| transferase activity | 3.97138602499442 | bayes_pls_golite062009 |
| protein tyrosine kinase activity | 2.8153155526437 | bayes_pls_golite062009 |
| binding | 2.74863538127007 | bayes_pls_golite062009 |
| molecular transducer activity | 2.40586892801446 | bayes_pls_golite062009 |
| signal transducer activity | 2.40586892801446 | bayes_pls_golite062009 |
| protein binding | 2.276111749106 | bayes_pls_golite062009 |
| tubulin binding | 2.18641675163967 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 2.12615078788254 | bayes_pls_golite062009 |
| receptor signaling protein activity | 2.10379226653669 | bayes_pls_golite062009 |
| ATP binding | 1.97600611746091 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 1.93596671856664 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 1.90928021591891 | bayes_pls_golite062009 |
| microtubule binding | 1.88110801192607 | bayes_pls_golite062009 |
| actin binding | 1.87817875565699 | bayes_pls_golite062009 |
| receptor signaling protein serine/threonine kinase activity | 1.81249386965144 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 1.7769021678395 | bayes_pls_golite062009 |
| transmembrane receptor activity | 1.6878868450299 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 1.65732943334212 | bayes_pls_golite062009 |
| ribonucleotide binding | 1.65726906484847 | bayes_pls_golite062009 |
| purine nucleotide binding | 1.63763394711025 | bayes_pls_golite062009 |
| nucleotide binding | 1.63195828048121 | bayes_pls_golite062009 |
| insulin receptor substrate binding | 1.62657794525303 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 1.6084489855403 | bayes_pls_golite062009 |
| receptor activity | 1.57112777506542 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine kinase activity | 1.4571078357189 | bayes_pls_golite062009 |
| gamma-tubulin binding | 1.28511591054866 | bayes_pls_golite062009 |
| kinase binding | 1.26086833316556 | bayes_pls_golite062009 |
| phosphoinositide 3-kinase binding | 1.25285260301349 | bayes_pls_golite062009 |
| catalytic activity | 1.21655087018101 | bayes_pls_golite062009 |
| transporter activity | 1.11833481501707 | bayes_pls_golite062009 |
| protein kinase binding | 1.06030596516506 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.97575992765505 | bayes_pls_golite062009 |
| cyclin-dependent protein kinase activity | 0.959360414036299 | bayes_pls_golite062009 |
| MAP kinase activity | 0.81943579965027 | bayes_pls_golite062009 |
| actin filament binding | 0.794152600084 | bayes_pls_golite062009 |
| nucleic acid binding | 0.794058505655489 | bayes_pls_golite062009 |
| transcription regulator activity | 0.775404673285876 | bayes_pls_golite062009 |
| DNA binding | 0.714163549867672 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.705905455086486 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.612883428421652 | bayes_pls_golite062009 |
| protein complex binding | 0.599713385230491 | bayes_pls_golite062009 |
| transcription factor activity | 0.563262875317016 | bayes_pls_golite062009 |
| protein serine/threonine/tyrosine kinase activity | 0.48345772948903 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.450699332958421 | bayes_pls_golite062009 |
| magnesium ion binding | 0.393328812780268 | bayes_pls_golite062009 |
| MAP kinase kinase kinase activity | 0.37115026509016 | bayes_pls_golite062009 |
| MAP kinase kinase activity | 0.35402045013148 | bayes_pls_golite062009 |
| transmembrane receptor protein serine/threonine kinase activity | 0.26602283402868 | bayes_pls_golite062009 |
| transforming growth factor beta receptor activity | 0.26602283402868 | bayes_pls_golite062009 |
| insulin receptor activity | 0.237134032032089 | bayes_pls_golite062009 |
| SH2 domain binding | 0.226760162354251 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 0.148194101970458 | bayes_pls_golite062009 |
| growth factor binding | 0.0526340287295695 | bayes_pls_golite062009 |
| transforming growth factor beta receptor activity, type I | 0.0506751594607393 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.0040394359628233 | bayes_pls_golite062009 |
|
Region A: Residues: [567-696] |
1 11 21 31 41 51
| | | | | |
1 NWDLLSKKKV QPPFKPNVQN DLDVSNFDKE FTNTNVKNIN IVSNVDPANA STPLSNTIQD 60
61 RFRGFTFVNK SIDEQFQNLG LQENEETDNL HACRTTTHSS VNSINSHGNP RTVDANDPVA 120
121 DTVFGETFEA
|
| Detection Method: | |
| Confidence: | 95.69897 |
| Match: | 1o6lA |
| Description: | Pkb kinase |
Matching Structure (courtesy of the PDB): |
|
