| Protein: | sck2 |
| Organism: | Schizosaccharomyces pombe |
| Length: | 646 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for sck2.
| Description | E-value | Query Range |
Subject Range |
|
|
377.0 | [0..1] | [630..1] |
|
|
377.0 | [0..23] | [608..3] |
|
|
374.0 | [0..9] | [614..203] |
|
|
373.0 | [0..3] | [626..40] |
|
|
372.0 | [0..2] | [598..559] |
|
|
370.0 | [0..2] | [606..36] |
|
|
369.0 | [0..195] | [610..31] |
|
|
367.0 | [0..6] | [598..598] |
|
|
365.0 | [0..25] | [608..247] |
|
Region A: Residues: [1-172] |
1 11 21 31 41 51
| | | | | |
1 MMNKWAKNWF GLSKKSVSTN SAKGSLPRSP LASIQTNQPV EEGEGGSLPS VSNLGPSSID 60
61 HPMEEFASDQ STVGNRNSND ILPEVDHEPS GYLKLQIGSL VLGGPHTDAA LAMECSRLNQ 120
121 LFVVVQFGTT EFVSPPLKWE SPGRDIGTSS RDSANVSRSS SMMSSHPIPT PA
|
| Detection Method: |  |
| Confidence: | 0.954 |
| Match: | 2hglA |
| Description: | No description for 2hglA was found. |
|
Region A: Residues: [173-258] |
1 11 21 31 41 51
| | | | | |
1 IQRTSSIPNP LTPSYVVFDV AKPVPIDVNI YDHGNNNEFV GRTYIHPSYN YGQFEQFCNS 60
61 VEVSPAYNRM VDLRLSLNTV FQPLSQ
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [259-541] |
1 11 21 31 41 51
| | | | | |
1 HSYGPDDFVP LKLIGKGTFG QVYLVRKKDT ERVYAMKVLS KKVIVRRKEV AHTVGERDIL 60
61 VQTSAADSPF IVALRFSFQT PKDLYLVTDY MAGGELFWHL QKSVRFPEER AKFYIAELLL 120
121 ALQALHKRGI VYRDLKPENI LLDVQGHIAL CDFGLSKANL SVGTTTRTFC GTTDYLAPEV 180
181 ILDEAGYDMM VDFWSLGVLL YEMTCGWSPF YADNTQQLYK NIVFGKVRFP RGLLSVEARD 240
241 LIKLLLNRNP KHRLGAHGDV EEVMKHPFFD GIDWKKLAAK EIS
|
| Detection Method: | |
| Confidence: | 69.69897 |
| Match: | 1h1wA |
| Description: | 3-phosphoinositide dependent protein kinase-1 Pdk1 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| phosphotransferase activity, alcohol group as acceptor | 5.49988294224815 | bayes_pls_golite062009 |
| protein kinase activity | 5.4586557943719 | bayes_pls_golite062009 |
| kinase activity | 5.3287080791198 | bayes_pls_golite062009 |
| cyclic nucleotide-dependent protein kinase activity | 4.97855712164511 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 4.96052051118534 | bayes_pls_golite062009 |
| cAMP-dependent protein kinase activity | 4.66277812893755 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 4.46381887831481 | bayes_pls_golite062009 |
| transferase activity | 3.97138602499442 | bayes_pls_golite062009 |
| protein tyrosine kinase activity | 2.8153155526437 | bayes_pls_golite062009 |
| binding | 2.74863538127007 | bayes_pls_golite062009 |
| transmembrane receptor activity | 2.59526003830791 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 2.54265774272269 | bayes_pls_golite062009 |
| molecular transducer activity | 2.40586892801446 | bayes_pls_golite062009 |
| signal transducer activity | 2.40586892801446 | bayes_pls_golite062009 |
| receptor activity | 2.39311927684508 | bayes_pls_golite062009 |
| tubulin binding | 2.18641675163967 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine kinase activity | 2.16831387024372 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 2.12615078788254 | bayes_pls_golite062009 |
| receptor signaling protein activity | 2.10379226653669 | bayes_pls_golite062009 |
| ATP binding | 1.97600611746091 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 1.93596671856664 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 1.90928021591891 | bayes_pls_golite062009 |
| microtubule binding | 1.88110801192607 | bayes_pls_golite062009 |
| actin binding | 1.87817875565699 | bayes_pls_golite062009 |
| acetylcholine receptor activator activity | 1.83545227594542 | bayes_pls_golite062009 |
| phosphoinositide 3-kinase binding | 1.82515074380651 | bayes_pls_golite062009 |
| receptor signaling protein serine/threonine kinase activity | 1.81249386965144 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 1.65732943334212 | bayes_pls_golite062009 |
| ribonucleotide binding | 1.65726906484847 | bayes_pls_golite062009 |
| purine nucleotide binding | 1.63763394711025 | bayes_pls_golite062009 |
| nucleotide binding | 1.63195828048121 | bayes_pls_golite062009 |
| insulin receptor substrate binding | 1.62657794525303 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 1.32254739984688 | bayes_pls_golite062009 |
| gamma-tubulin binding | 1.28511591054866 | bayes_pls_golite062009 |
| kinase binding | 1.26086833316556 | bayes_pls_golite062009 |
| ErbB-3 class receptor binding | 1.25765701903393 | bayes_pls_golite062009 |
| protein binding | 1.22565748038754 | bayes_pls_golite062009 |
| catalytic activity | 1.21655087018101 | bayes_pls_golite062009 |
| transporter activity | 1.11833481501707 | bayes_pls_golite062009 |
| protein kinase binding | 1.06030596516506 | bayes_pls_golite062009 |
| ErbB-2 class receptor binding | 1.02996109010965 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.97575992765505 | bayes_pls_golite062009 |
| cyclin-dependent protein kinase activity | 0.959360414036299 | bayes_pls_golite062009 |
| growth factor binding | 0.86076618871384 | bayes_pls_golite062009 |
| MAP kinase activity | 0.81943579965027 | bayes_pls_golite062009 |
| actin filament binding | 0.794152600084 | bayes_pls_golite062009 |
| nucleic acid binding | 0.794058505655489 | bayes_pls_golite062009 |
| transcription regulator activity | 0.775404673285876 | bayes_pls_golite062009 |
| DNA binding | 0.714163549867672 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.705905455086486 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.612883428421652 | bayes_pls_golite062009 |
| transcription factor activity | 0.563262875317016 | bayes_pls_golite062009 |
| protein serine/threonine/tyrosine kinase activity | 0.48345772948903 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.450699332958421 | bayes_pls_golite062009 |
| protein kinase C activity | 0.41587987561486 | bayes_pls_golite062009 |
| magnesium ion binding | 0.393328812780268 | bayes_pls_golite062009 |
| MAP kinase kinase kinase activity | 0.37115026509016 | bayes_pls_golite062009 |
| MAP kinase kinase activity | 0.35402045013148 | bayes_pls_golite062009 |
| insulin receptor binding | 0.266450215230107 | bayes_pls_golite062009 |
| protein complex binding | 0.239339759110451 | bayes_pls_golite062009 |
| insulin receptor activity | 0.237134032032089 | bayes_pls_golite062009 |
| SH2 domain binding | 0.226760162354251 | bayes_pls_golite062009 |
| transmembrane receptor protein serine/threonine kinase activity | 0.20643152368029 | bayes_pls_golite062009 |
| transforming growth factor beta receptor activity | 0.20643152368029 | bayes_pls_golite062009 |
| receptor binding | 0.197402253061255 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 0.148194101970458 | bayes_pls_golite062009 |
| peptide binding | 0.118578378753757 | bayes_pls_golite062009 |
| transforming growth factor beta receptor activity, type I | 0.0506751594607393 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.0040394359628233 | bayes_pls_golite062009 |
|
Region A: Residues: [542-646] |
1 11 21 31 41 51
| | | | | |
1 PPFKPIVEGE IDVSNFDVEF TNKAIDRDFS STDEMSTSAP LSSTVQNGFK GFTYIDASAM 60
61 DEAFGYHNSN DSASSISSQD DYSKDNSDMD LNRANDEVFM GQIDP
|
| Detection Method: | |
| Confidence: | 95.045757 |
| Match: | 2jdoA |
| Description: | No description for 2jdoA was found. |
