| Protein: | Nek2-PA |
| Organism: | Drosophila melanogaster |
| Length: | 735 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Nek2-PA.
| Description | E-value | Query Range |
Subject Range |
|
|
371.0 | [0..4] | [724..41] |
|
Region A: Residues: [1-288] |
1 11 21 31 41 51
| | | | | |
1 MSGEESAGMD FSQKTLQDYE VLAVMGNGSF GTCYKVRDKS TGELFAWKGM NYDELDEAKC 60
61 DALVSEISVL RQLQHPNIVQ YYHHLVNREA KSVYIVMECC AGGDLAQIVQ RARSQRQRFE 120
121 EPYIWRVLFQ LCRALQVCHN KIPNGTILHR DIKPANIFLD AAGNAKLGDF GLARMLRRDQ 180
181 SFAASFVGTP HYMSPELVKG RKYDRKSDVW AVGCLVYEMC ALRPPFRGRA FDQLSEKIAQ 240
241 GEFSRIPAIY STDLQEIIAF MLAVDHEQRP GIEVIIRHPL VVRNISEL
|
| Detection Method: |  |
| Confidence: | 61.154902 |
| Match: | 2javA |
| Description: | No description for 2javA was found. |
| Term | Confidence | Notes |
| phosphotransferase activity, alcohol group as acceptor | 5.49988294224815 | bayes_pls_golite062009 |
| protein kinase activity | 5.4586557943719 | bayes_pls_golite062009 |
| kinase activity | 5.3287080791198 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 4.96052051118534 | bayes_pls_golite062009 |
| cyclin-dependent protein kinase activity | 4.62392503670521 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 4.46381887831481 | bayes_pls_golite062009 |
| transferase activity | 3.97138602499442 | bayes_pls_golite062009 |
| binding | 2.74863538127007 | bayes_pls_golite062009 |
| phosphoinositide 3-kinase binding | 2.41610417530517 | bayes_pls_golite062009 |
| protein binding | 2.276111749106 | bayes_pls_golite062009 |
| tubulin binding | 2.18641675163967 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 2.12615078788254 | bayes_pls_golite062009 |
| ATP binding | 1.97600611746091 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 1.93596671856664 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 1.93176092222748 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 1.90928021591891 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 1.90354666768303 | bayes_pls_golite062009 |
| microtubule binding | 1.88110801192607 | bayes_pls_golite062009 |
| telethonin binding | 1.75733591474207 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 1.71452519680794 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 1.65732943334212 | bayes_pls_golite062009 |
| ribonucleotide binding | 1.65726906484847 | bayes_pls_golite062009 |
| purine nucleotide binding | 1.63763394711025 | bayes_pls_golite062009 |
| nucleotide binding | 1.63195828048121 | bayes_pls_golite062009 |
| insulin receptor substrate binding | 1.62657794525303 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 1.6084489855403 | bayes_pls_golite062009 |
| transcription regulator activity | 1.56748951434625 | bayes_pls_golite062009 |
| protein tyrosine kinase activity | 1.3898059094397 | bayes_pls_golite062009 |
| receptor signaling protein serine/threonine kinase activity | 1.38496328649031 | bayes_pls_golite062009 |
| DNA binding | 1.35333135345112 | bayes_pls_golite062009 |
| actin binding | 1.33479685165255 | bayes_pls_golite062009 |
| gamma-tubulin binding | 1.28511591054866 | bayes_pls_golite062009 |
| receptor signaling protein activity | 1.27291233344322 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 1.27184436658773 | bayes_pls_golite062009 |
| insulin receptor activity | 1.22442673174261 | bayes_pls_golite062009 |
| catalytic activity | 1.21655087018101 | bayes_pls_golite062009 |
| nucleic acid binding | 1.16049201286103 | bayes_pls_golite062009 |
| transcription factor activity | 1.10928254946881 | bayes_pls_golite062009 |
| transcription activator activity | 0.997272622653026 | bayes_pls_golite062009 |
| PTB domain binding | 0.9900774724568 | bayes_pls_golite062009 |
| alpha-actinin binding | 0.877087652539674 | bayes_pls_golite062009 |
| insulin-like growth factor receptor binding | 0.872782211382796 | bayes_pls_golite062009 |
| MAP kinase activity | 0.81943579965027 | bayes_pls_golite062009 |
| insulin binding | 0.614254468447749 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.612883428421652 | bayes_pls_golite062009 |
| transporter activity | 0.595111702412257 | bayes_pls_golite062009 |
| protein serine/threonine/tyrosine kinase activity | 0.48345772948903 | bayes_pls_golite062009 |
| protein kinase C activity | 0.41587987561486 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.41384976209545 | bayes_pls_golite062009 |
| magnesium ion binding | 0.393328812780268 | bayes_pls_golite062009 |
| MAP kinase kinase kinase activity | 0.37115026509016 | bayes_pls_golite062009 |
| MAP kinase kinase activity | 0.35402045013148 | bayes_pls_golite062009 |
| protein complex binding | 0.343240719858581 | bayes_pls_golite062009 |
| signal transducer activity | 0.270054246024761 | bayes_pls_golite062009 |
| molecular transducer activity | 0.270054246024761 | bayes_pls_golite062009 |
| insulin receptor binding | 0.266450215230107 | bayes_pls_golite062009 |
| cation channel activity | 0.245400615103891 | bayes_pls_golite062009 |
| actin filament binding | 0.2403700250846 | bayes_pls_golite062009 |
| SH2 domain binding | 0.226760162354251 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.0922946791401962 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 0.0556163711947139 | bayes_pls_golite062009 |
| transmembrane receptor activity | 0.00652065412910241 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.0040394359628233 | bayes_pls_golite062009 |
|
Region A: Residues: [289-509] |
1 11 21 31 41 51
| | | | | |
1 DGKFPILVDS GEDFYTLPSG ARLFEDEEED GVHPELSSTM FTEQYSFNEG YGQRRLSVTG 60
61 VFTPDLRSEL FYSAKRKIFP AKKLQLSDPS LYESIRREER AEERQVELAE ERRRKKDQEQ 120
121 QKRDQELLKE APSSPRALTQ NIFDEVLKTR LHAIRAQESL LQQKLEELQT REQELQLAEQ 180
181 RVQTLERQMQ EKLLQQEKHT CSCRQPIAPP IPPRKPAKSH H
|
| Detection Method: | |
| Confidence: | 1.49 |
| Match: | 2i1jA |
| Description: | No description for 2i1jA was found. |
|
Region A: Residues: [510-668] |
1 11 21 31 41 51
| | | | | |
1 DDTYCTIELN ETSPTVAKLN LATLPAPKSL NTLRKVTFKS PQKFVTYGIE NMPPPAVKPA 60
61 VNPPPTGVPM QMSVSSNDSG DSQASSTRRK SILSLFGLSR GSKATSKSLP SVNQVAQAAA 120
121 TRVQRPPLAV KPPITQEQPA EVPPVANLWT KEQKKQAFE
|
| Detection Method: | |
| Confidence: | 1.36 |
| Match: | 1h1kI |
| Description: | THE BLUETONGUE VIRUS (BTV) CORE BINDS DSRNA |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [669-735] |
1 11 21 31 41 51
| | | | | |
1 LLAAMNAAER EASGGGVVGS GPGGARRQHL RQSVRERNST LQRNRMRRSL VVATGHQKLT 60
61 TRDQMVI
|
| Detection Method: | |
| Confidence: | 7.69897 |
| Match: | 1ul7A |
| Description: | Solution structure of kinase associated domain 1 of mouse MAP/microtubule affinity-regulating kinase 3 |
Matching Structure (courtesy of the PDB): |
|
