| Protein: | CG7747-PA |
| Organism: | Drosophila melanogaster |
| Length: | 517 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG7747-PA.
| Description | E-value | Query Range |
Subject Range |
|
|
510.0 | [0..12] | [517..1] |
|
Region A: Residues: [1-106] |
1 11 21 31 41 51
| | | | | |
1 MGKRQHQKDK MYLTYTEWSE LYGGKKVESL ENDHVKFKRL PFEHCCITMA PYEMPYCDLQ 60
61 GNVFEYEAIL KFLKTFKVNP ITGQKMDSKS LVKLNFHRNA NDEYHC
|
| Detection Method: |  |
| Confidence: | 14.69897 |
| Match: | 2c2lA |
| Description: | Crystal structure of the CHIP U-box E3 ubiquitin ligase |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| ubiquitin-protein ligase activity | 5.78506998502716 | bayes_pls_golite062009 |
| small conjugating protein ligase activity | 5.55686022186257 | bayes_pls_golite062009 |
| 4.77196423114965 | bayes_pls_golite062009 | |
| acid-amino acid ligase activity | 4.59153177011595 | bayes_pls_golite062009 |
| ligase activity, forming carbon-nitrogen bonds | 3.07217714843839 | bayes_pls_golite062009 |
| RNA binding | 3.04658201081989 | bayes_pls_golite062009 |
| binding | 2.58862749918018 | bayes_pls_golite062009 |
| transcription regulator activity | 1.62076236255768 | bayes_pls_golite062009 |
| protein binding | 1.49775478023418 | bayes_pls_golite062009 |
| ubiquitin-ubiquitin ligase activity | 1.37401357060257 | bayes_pls_golite062009 |
| peptidase activity | 1.26418257706548 | bayes_pls_golite062009 |
| nucleic acid binding | 1.22180889694654 | bayes_pls_golite062009 |
| small conjugating protein-specific protease activity | 1.2126425713931 | bayes_pls_golite062009 |
| peptidase activity, acting on L-amino acid peptides | 1.09332582339395 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 1.0455933268847 | bayes_pls_golite062009 |
| ubiquitin-specific protease activity | 1.03469202541773 | bayes_pls_golite062009 |
| DNA binding | 1.00346149950987 | bayes_pls_golite062009 |
| ligase activity | 0.63517530468004 | bayes_pls_golite062009 |
| endopeptidase activity | 0.573573811866385 | bayes_pls_golite062009 |
| cysteine-type peptidase activity | 0.50197530717959 | bayes_pls_golite062009 |
| transcription factor binding | 0.39685947299825 | bayes_pls_golite062009 |
| hydrolase activity | 0.39313698408945 | bayes_pls_golite062009 |
| transcription factor activity | 0.382098789505496 | bayes_pls_golite062009 |
| ubiquitin thiolesterase activity | 0.265769062717221 | bayes_pls_golite062009 |
| catalytic activity | 0.14112008370434 | bayes_pls_golite062009 |
| SUMO polymer binding | 0.0588467253656506 | bayes_pls_golite062009 |
| antigen binding | 0.0191313108005651 | bayes_pls_golite062009 |
|
Region A: Residues: [107-153] |
1 11 21 31 41 51
| | | | | |
1 PALFKPFSKN SHIVAVATTG NVYCWEAIDQ LNIKTKNWKD LVDDTPF
|
| Detection Method: | |
| Confidence: | 2.02 |
| Match: | 2bayA |
| Description: | Crystal structure of the Prp19 U-box dimer |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| ubiquitin-protein ligase activity | 5.39046951458785 | bayes_pls_golite062009 |
| small conjugating protein ligase activity | 5.16068345159314 | bayes_pls_golite062009 |
| 4.72885746116757 | bayes_pls_golite062009 | |
| acid-amino acid ligase activity | 4.24782814163304 | bayes_pls_golite062009 |
| RNA binding | 3.00624142341404 | bayes_pls_golite062009 |
| ligase activity, forming carbon-nitrogen bonds | 2.79292110382407 | bayes_pls_golite062009 |
| binding | 2.51064774590911 | bayes_pls_golite062009 |
| transcription regulator activity | 1.58888342715984 | bayes_pls_golite062009 |
| protein binding | 1.38611309393826 | bayes_pls_golite062009 |
| peptidase activity | 1.25068211953419 | bayes_pls_golite062009 |
| nucleic acid binding | 1.21287410633544 | bayes_pls_golite062009 |
| peptidase activity, acting on L-amino acid peptides | 1.07404910011569 | bayes_pls_golite062009 |
| ubiquitin-ubiquitin ligase activity | 1.03473176569589 | bayes_pls_golite062009 |
| small conjugating protein-specific protease activity | 1.02238152139385 | bayes_pls_golite062009 |
| DNA binding | 1.00709690792313 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 0.951861817643521 | bayes_pls_golite062009 |
| ubiquitin-specific protease activity | 0.821040441472875 | bayes_pls_golite062009 |
| endopeptidase activity | 0.567550697522097 | bayes_pls_golite062009 |
| ligase activity | 0.424146907469434 | bayes_pls_golite062009 |
| hydrolase activity | 0.421529723274632 | bayes_pls_golite062009 |
| transcription factor activity | 0.3885123241249 | bayes_pls_golite062009 |
| cysteine-type peptidase activity | 0.356312424125648 | bayes_pls_golite062009 |
| transcription factor binding | 0.265920091724011 | bayes_pls_golite062009 |
| catalytic activity | 0.168711389690753 | bayes_pls_golite062009 |
| ubiquitin thiolesterase activity | 0.0136579100966835 | bayes_pls_golite062009 |
|
Region A: Residues: [154-276] |
1 11 21 31 41 51
| | | | | |
1 QRKDIITIQD PQKLEKYDIS TFYHIKKNLR VLTEEEQQER KNPASGRIKT MNLETKETLE 60
61 QLQQDYQPAE EEASTSKRTA DKFNAAHYST GAVAASFTST AMVPVSQIEA AIIDDDLVKY 120
121 ERV
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [277-517] |
1 11 21 31 41 51
| | | | | |
1 KKKGYVRLNT NLGPLNLELF CDQTPRACDN FIKHCANGYY NNVMFHRSIR NFIVQGGDPT 60
61 GSGSGGESIW GKKFEDEFKP NLTHTGRGVL SMANSGPNTN GSQFFITYRS CKHLDGKHTI 120
121 FGKLVGGLDT LQKMENIEVD NKDRPIEDII IESSQVFVNP FAEAAEQLAK EREEEAAGKE 180
181 EIVKKEEQQK RMKEPLKVYR EGVGKYLKLQ TVAKKPEAPL TSAQAAKKKK LANGFGDFSS 240
241 W
|
| Detection Method: | |
| Confidence: | 53.30103 |
| Match: | 1xyhA |
| Description: | Crystal Structure of Recombinant Human Cyclophilin J |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| peptidyl-prolyl cis-trans isomerase activity | 3.73853378771688 | bayes_pls_golite062009 |
| cis-trans isomerase activity | 3.66963215732405 | bayes_pls_golite062009 |
| RNA binding | 2.94609837984526 | bayes_pls_golite062009 |
| ubiquitin-protein ligase activity | 2.19800591333648 | bayes_pls_golite062009 |
| isomerase activity | 1.96529188741504 | bayes_pls_golite062009 |
| small conjugating protein ligase activity | 1.9120328189871 | bayes_pls_golite062009 |
| binding | 1.46018233647024 | bayes_pls_golite062009 |
| mRNA binding | 1.45537055700871 | bayes_pls_golite062009 |
| unfolded protein binding | 1.38124355054041 | bayes_pls_golite062009 |
| acid-amino acid ligase activity | 1.29596840005227 | bayes_pls_golite062009 |
| nucleic acid binding | 0.939772862764466 | bayes_pls_golite062009 |
| catalytic activity | 0.748655649755714 | bayes_pls_golite062009 |
| ligase activity, forming carbon-nitrogen bonds | 0.38915122244271 | bayes_pls_golite062009 |
| drug binding | 0.36339132904137 | bayes_pls_golite062009 |
| hydrolase activity | 0.363074952403273 | bayes_pls_golite062009 |
| protein binding | 0.130251391659493 | bayes_pls_golite062009 |
