| Protein: | Iswi-PA, Iswi-PB... |
| Organism: | Drosophila melanogaster |
| Length: | 1027 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Iswi-PA, Iswi-PB....
| Description | E-value | Query Range |
Subject Range |
|
|
722.0 | [0..1] | [1022..1] |
|
Region A: Residues: [1-115] |
1 11 21 31 41 51
| | | | | |
1 MSKTDTAAVE ATEENSNETT SDAATSSSGE KEAEFDNKIE ADRSRRFDFL LKQTEIFTHF 60
61 MTNSAKSPTK PKGRPKKIKD KDKEKDVADH RHRKTEQEED EELLAEDSAT KEIFR
|
| Detection Method: |  |
| Confidence: | 4.09691 |
| Match: | 2b2uA |
| Description: | Tandem chromodomains of human CHD1 complexed with Histone H3 Tail containing trimethyllysine 4 and dimethylarginine 2 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| chromatin binding | 3.84065302930105 | bayes_pls_golite062009 |
| transcription regulator activity | 3.64390820819794 | bayes_pls_golite062009 |
| binding | 3.06758476214113 | bayes_pls_golite062009 |
| protein binding | 2.66728689880621 | bayes_pls_golite062009 |
| transcription elongation regulator activity | 2.46353586381231 | bayes_pls_golite062009 |
| transcription repressor activity | 2.45308491935607 | bayes_pls_golite062009 |
| nucleic acid binding | 2.19167058827256 | bayes_pls_golite062009 |
| DNA binding | 2.05514577638135 | bayes_pls_golite062009 |
| histone binding | 2.00388175060339 | bayes_pls_golite062009 |
| transcription activator activity | 1.46529895769882 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 1.10020047862576 | bayes_pls_golite062009 |
| methylated histone residue binding | 1.03331560428208 | bayes_pls_golite062009 |
| catalytic activity | 0.14067200158938 | bayes_pls_golite062009 |
|
Region A: Residues: [116-668] |
1 11 21 31 41 51
| | | | | |
1 FDASPAYIKS GEMRDYQIRG LNWMISLYEN GINGILADEM GLGKTLQTIS LLGYLKHFKN 60
61 QAGPHIVIVP KSTLQNWVNE FKKWCPSLRA VCLIGDQDTR NTFIRDVLMP GEWDVCVTSY 120
121 EMCIREKSVF KKFNWRYLVI DEAHRIKNEK SKLSEILREF KTANRLLITG TPLQNNLHEL 180
181 WALLNFLLPD VFNSSEDFDE WFNTNTCLGD DALITRLHAV LKPFLLRRLK AEVEKRLKPK 240
241 KEMKIFVGLS KMQRDWYTKV LLKDIDVVNG AGKVEKMRLQ NILMQLRKCT NHPYLFDGAE 300
301 PGPPYTTDTH LVYNSGKMAI LDKLLPKLQE QGSRVLIFSQ MTRMLDILED YCHWRNYNYC 360
361 RLDGQTPHED RNRQIQEFNM DNSAKFLFML STRAGGLGIN LATADVVIIY DSDWNPQMDL 420
421 QAMDRAHRIG QKKQVRVFRL ITESTVEEKI VERAEVKLRL DKMVIQGGRL VDNRSNQLNK 480
481 DEMLNIIRFG ANQVFSSKET DITDEDIDVI LERGEAKTAE QKAALDSLGE SSLRTFTMDT 540
541 NGEAGTSSVY QFE
|
| Detection Method: | |
| Confidence: | 85.154902 |
| Match: | 1z3iX |
| Description: | Structure of the SWI2/SNF2 chromatin remodeling domain of eukaryotic Rad54 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| general RNA polymerase II transcription factor activity | 3.1726526166851 | bayes_pls_golite062009 |
| binding | 2.64537357529343 | bayes_pls_golite062009 |
| nucleic acid binding | 2.51683451033161 | bayes_pls_golite062009 |
| DNA binding | 2.12258000781149 | bayes_pls_golite062009 |
| transcription regulator activity | 2.09345198747025 | bayes_pls_golite062009 |
| structural constituent of ribosome | 1.47858140861683 | bayes_pls_golite062009 |
| DNA-dependent ATPase activity | 1.23094623498843 | bayes_pls_golite062009 |
| protein binding | 1.22129154759482 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 1.21658213854831 | bayes_pls_golite062009 |
| ribonucleotide binding | 1.21652144153182 | bayes_pls_golite062009 |
| purine nucleotide binding | 1.21571071905795 | bayes_pls_golite062009 |
| nucleotide binding | 1.20347573865566 | bayes_pls_golite062009 |
| motor activity | 1.14667913749579 | bayes_pls_golite062009 |
| transcription elongation regulator activity | 1.11383295816593 | bayes_pls_golite062009 |
| histone acetyltransferase activity | 1.05990253628867 | bayes_pls_golite062009 |
| lysine N-acetyltransferase activity | 1.05990253628867 | bayes_pls_golite062009 |
| catalytic activity | 1.00104173493322 | bayes_pls_golite062009 |
| transcription activator activity | 0.889929694023098 | bayes_pls_golite062009 |
| transcription factor activity | 0.887108427603557 | bayes_pls_golite062009 |
| structural molecule activity | 0.86514677273731 | bayes_pls_golite062009 |
| protein-DNA loading ATPase activity | 0.729056749897011 | bayes_pls_golite062009 |
| steroid hormone receptor binding | 0.647625526012423 | bayes_pls_golite062009 |
| structure-specific DNA binding | 0.620212706423176 | bayes_pls_golite062009 |
| helicase activity | 0.6191010101321 | bayes_pls_golite062009 |
| microtubule motor activity | 0.60036517876321 | bayes_pls_golite062009 |
| DNA helicase activity | 0.57378485697982 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 0.543891899378373 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 0.500462538667228 | bayes_pls_golite062009 |
| DNA clamp loader activity | 0.49811753387851 | bayes_pls_golite062009 |
| double-stranded DNA binding | 0.49000746592281 | bayes_pls_golite062009 |
| guanyl nucleotide binding | 0.388587892299301 | bayes_pls_golite062009 |
| guanyl ribonucleotide binding | 0.372638007722845 | bayes_pls_golite062009 |
| GTP binding | 0.364508542344128 | bayes_pls_golite062009 |
| hormone receptor binding | 0.351501100511918 | bayes_pls_golite062009 |
| centromeric DNA binding | 0.322818640526369 | bayes_pls_golite062009 |
| ATP-dependent helicase activity | 0.29664013896754 | bayes_pls_golite062009 |
| purine NTP-dependent helicase activity | 0.29664013896754 | bayes_pls_golite062009 |
| translation regulator activity | 0.29096092258568 | bayes_pls_golite062009 |
| translation factor activity, nucleic acid binding | 0.274994961137851 | bayes_pls_golite062009 |
| ATP-dependent DNA helicase activity | 0.24825301806267 | bayes_pls_golite062009 |
| nuclear hormone receptor binding | 0.246160342138071 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 0.243902356228423 | bayes_pls_golite062009 |
| GTPase activity | 0.234351968078991 | bayes_pls_golite062009 |
| ATP binding | 0.1860481660648 | bayes_pls_golite062009 |
| RNA helicase activity | 0.18426050934025 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 0.152859582615242 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.147579541298736 | bayes_pls_golite062009 |
| RNA-dependent ATPase activity | 0.14606996093053 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 0.138615225841109 | bayes_pls_golite062009 |
| pyrophosphatase activity | 0.133017653323467 | bayes_pls_golite062009 |
| ATP-dependent RNA helicase activity | 0.13050483816765 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides | 0.113504049290503 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 0.111293884322157 | bayes_pls_golite062009 |
| actin binding | 0.00482938540552702 | bayes_pls_golite062009 |
|
Region A: Residues: [669-1027] |
1 11 21 31 41 51
| | | | | |
1 GEDWREKQKL NALGNWIEPP KRERKANYAV DAYFREALRV SEPKAPKAPR PPKQPIVQDF 60
61 QFFPPRLFEL LDQEIYYFRK TVGYKVPKNT ELGSDATKVQ REEQRKIDEA EPLTEEEIQE 120
121 KENLLSQGFT AWTKRDFNQF IKANEKYGRD DIDNIAKDVE GKTPEEVIEY NAVFWERCTE 180
181 LQDIERIMGQ IERGEGKIQR RLSIKKALDQ KMSRYRAPFH QLRLQYGNNK GKNYTEIEDR 240
241 FLVCMLHKLG FDKENVYEEL RAAIRASPQF RFDWFIKSRT ALELQRRCNT LITLIERENI 300
301 ELEEKERAEK KKKAPKGSVS AGSGSASSNT PAPAPQPKAS QKRKSEVVAT SSNSKKKKK
|
| Detection Method: | |
| Confidence: | 59.522879 |
| Match: | 1ofcX |
| Description: | nucleosome recognition module of ISWI ATPase |
Matching Structure (courtesy of the PDB): |
|
