YRC Public Data Repository - Protein Structure Prediction

Protein:	SPUD_PSEAE
Organism:	Pseudomonas aeruginosa PAO1
Length:	367 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPUD_PSEAE.

Description	E-value	Query Range	Subject Range
gi\|94414865, gi\|... - gi\|94414865\|ref\|ZP_01294719.1\| hypothetical protein PaerP_01003445 [Pseudomonas aeruginosa PA7], gi\|...	2.0E-91	[1..367]	[1..367]
gi\|114705308, gi... - gi\|114705308\|ref\|ZP_01438216.1\| putrescine-binding periplasmic protein [Fulvimarina pelagi HTCC2506]...	3.0E-90	[2..367]	[1..365]
gi\|254694281 - gi\|254694281\|ref\|ZP_05156109.1\| hypothetical protein Babob3T_06384 [Brucella abortus bv. 3 str. Tuly... gi\|225641449, gi... - gi\|225853084\|ref\|YP_002733317.1\| hypothetical protein BMEA_A1665 [Brucella melitensis ATCC 23457], g... gi\|148370872, gi... - gi\|148559615\|ref\|YP_001259475.1\| putative spermidine/putrescine ABC transporter, periplasmic spermid... gi\|254710643 - gi\|254710643\|ref\|ZP_05172454.1\| hypothetical protein BpinB_10306 [Brucella pinnipedialis B2/94] gi\|254708270 - gi\|254708270\|ref\|ZP_05170098.1\| hypothetical protein BpinM_15261 [Brucella pinnipedialis M163/99/10] gi\|254702329 - gi\|254702329\|ref\|ZP_05164157.1\| hypothetical protein Bsuib55_15918 [Brucella suis bv. 5 str. 513] gi\|17986694, gi\|... - gi\|17986694\|ref\|NP_539328.1\| putrescine-binding periplasmic protein [Brucella melitensis 16M], gi\|17... gi\|163674583, gi... - gi\|163843860\|ref\|YP_001628264.1\| hypothetical protein BSUIS_A1668 [Brucella suis ATCC 23445], gi\|163... gi\|25358052 - pir\|\|AE3303 putrescine-binding periplasmic protein BMEI0411 [imported] - Brucella melitensis (strain...	3.0E-86	[3..367]	[4..367]
gi\|254697934 - gi\|254697934\|ref\|ZP_05159762.1\| solute-binding family 1 protein [Brucella abortus bv. 2 str. 86/8/59... gi\|254730825 - gi\|254730825\|ref\|ZP_05189403.1\| solute-binding family 1 protein [Brucella abortus bv. 4 str. 292] gi\|82700414 - gi\|82700414\|ref\|YP_414988.1\| solute-binding family 1 protein [Brucella melitensis biovar Abortus 230... gi\|82616515 - gi\|82616515\|emb\|CAJ11584.1\| Bacterial periplasmic spermidine/putrescine-binding protein:Bacterial ex... gi\|62290491, gi\|... - gi\|62290491\|ref\|YP_222284.1\| spermidine/putrescine ABC transporter periplasmic spermidine/putrescine...	4.0E-86	[3..367]	[4..367]
gi\|161619552, gi... - gi\|161619552\|ref\|YP_001593439.1\| hypothetical protein BCAN_A1649 [Brucella canis ATCC 23365], gi\|161... gi\|254704858 - gi\|254704858\|ref\|ZP_05166686.1\| hypothetical protein Bsuib36_13253 [Brucella suis bv. 3 str. 686] gi\|23348468, gi\|... - gi\|23502475\|ref\|NP_698602.1\| spermidine/putrescine ABC transporter, periplasmic spermidine/putrescin...	2.0E-85	[3..367]	[4..367]
gi\|117623034, gi... - gi\|117623034\|ref\|YP_851947.1\| putrescine ABC transporter periplasmic substrate-binding protein [Esch... gi\|91209888, gi\|... - gi\|91209888\|ref\|YP_539874.1\| putrescine ABC transporter periplasmic substrate-binding protein [Esche... gi\|237707182, gi... - gi\|237707182\|ref\|ZP_04537663.1\| putrescine-binding periplasmic protein [Escherichia sp. 3_2_53FAA], ...	9.0E-84	[3..367]	[54..418]
gi\|26107277, gi\|... - gi\|26246877\|ref\|NP_752917.1\| putrescine ABC transporter periplasmic substrate-binding protein [Esche... gi\|227884182, gi... - gi\|227884182\|ref\|ZP_04001987.1\| putrescine ABC superfamily ATP binding cassette transporter periplas...	9.0E-84	[3..367]	[54..418]
gi\|70730024, gi\|... - gi\|70730024\|ref\|YP_259763.1\| putrescine ABC transporter, periplasmic putrescine-binding protein [Pse...	9.0E-84	[4..367]	[10..373]
gi\|113885937, gi... - gi\|113971253\|ref\|YP_735046.1\| extracellular solute-binding protein [Shewanella sp. MR-4], gi\|1138859... gi\|117921535, gi... - gi\|78686610\|ref\|ZP_00851375.1\| polyamine ABC transporter, periplasmic polyamine-binding protein [She...	3.0E-83	[2..367]	[22..387]
gi\|77385628, gi\|... - gi\|77461625\|ref\|YP_351132.1\| extracellular solute-binding protein [Pseudomonas fluorescens Pf0-1], g...	7.0E-83	[11..367]	[20..375]

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Predicted Domain #1

Region A:
Residues: [1-367]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMKRFGKTLL ALTLAGSVAG MAQAADNKVL HVYNWSDYIA PDTLEKFTKE TGIKVVYDVY  60
   61 DSNEVLEAKL LAGKSGYDVV VPSNSFLAKQ IKAGVYQKLD KSKLPNWKNL NKDLMHTLEV 120
  121 SDPGNEHAIP YMWGTIGIGY NPDKVKAAFG DNAPVDSWDL VFKPENIQKL KQCGVSFLDS 180
  181 PTEILPAALH YLGYKPDTDN PKELKAAEEL FLKIRPYVTY FHSSKYISDL ANGNICVAIG 240
  241 YSGDIYQAKS RAEEAKNKVT VKYNIPKEGA GSFFDMVAIP KDAENTEGAL AFVNFLMKPE 300
  301 IMAEITDVVQ FPNGNAAATP LVSEAIRNDP GIYPSEEVMK KLYTFPDLPA KTQRAMTRSW 360
  361 TKIKSGK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	79.522879
Match:	1a99A
Description:	Putrescine receptor (PotF)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
polyamine transmembrane transporter activity	6.4955392556526	bayes_pls_golite062009
polyamine-transporting ATPase activity	5.55983439723443	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances	5.10369591387353	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	5.10318083615538	bayes_pls_golite062009
ATPase activity, coupled to movement of substances	5.10318083615538	bayes_pls_golite062009
active transmembrane transporter activity	5.08926597039825	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	5.08835444171664	bayes_pls_golite062009
primary active transmembrane transporter activity	5.0778580713249	bayes_pls_golite062009
polyamine binding	4.52047643422812	bayes_pls_golite062009
ATPase activity, coupled	4.39934929410381	bayes_pls_golite062009
transporter activity	4.36277471796561	bayes_pls_golite062009
amine transmembrane transporter activity	4.06067446901213	bayes_pls_golite062009
transmembrane transporter activity	4.05122336499684	bayes_pls_golite062009
ATPase activity	4.04125376161476	bayes_pls_golite062009
substrate-specific transporter activity	3.47889550245964	bayes_pls_golite062009
anion transmembrane-transporting ATPase activity	3.25040168593981	bayes_pls_golite062009
inorganic anion transmembrane transporter activity	3.16446457499691	bayes_pls_golite062009
organic acid transmembrane transporter activity	3.1010430082527	bayes_pls_golite062009
carboxylic acid transmembrane transporter activity	3.08561402450657	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	2.87472545473244	bayes_pls_golite062009
putrescine transmembrane transporter activity	2.81060956700345	bayes_pls_golite062009
anion transmembrane transporter activity	2.77148301796671	bayes_pls_golite062009
peptide transporter activity	2.75577307623285	bayes_pls_golite062009
molybdate ion transmembrane transporter activity	2.58578176144479	bayes_pls_golite062009
molybdate transmembrane-transporting ATPase activity	2.58578176144479	bayes_pls_golite062009
hydrolase activity	2.41680852416007	bayes_pls_golite062009
amine binding	2.37157043664258	bayes_pls_golite062009
amino acid binding	2.19962484683312	bayes_pls_golite062009
oligopeptide transporter activity	1.91036692266394	bayes_pls_golite062009
ion transmembrane transporter activity	1.70693655091183	bayes_pls_golite062009
nucleoside-triphosphatase activity	1.70643051049474	bayes_pls_golite062009
pyrophosphatase activity	1.65646853917778	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	1.63520066802961	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	1.6341518946909	bayes_pls_golite062009
binding	1.54172013140566	bayes_pls_golite062009
amino acid transmembrane transporter activity	1.46567992263504	bayes_pls_golite062009
amino acid-transporting ATPase activity	0.991822522006045	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions	0.99134553005852	bayes_pls_golite062009
putrescine binding	0.973416867423461	bayes_pls_golite062009
amine-transporting ATPase activity	0.971052093204841	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	0.230402103022499	bayes_pls_golite062009
cation transmembrane transporter activity	0.119916745111395	bayes_pls_golite062009
sulfate transmembrane-transporting ATPase activity	0.0940079640524907	bayes_pls_golite062009
transition metal ion transmembrane transporter activity	0.00844917716785965	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: