| Protein: | KC11_YEAST |
| Organism: | Saccharomyces cerevisiae S288c |
| Length: | 538 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for KC11_YEAST.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..538] | [1..538] |
|
|
0.0 | [49..447] | [7..403] |
|
|
0.0 | [16..447] | [35..464] |
|
|
0.0 | [20..447] | [36..461] |
|
Region A: Residues: [1-111] |
1 11 21 31 41 51
| | | | | |
1 MSMPIASTTL AVNNLTNING NANFNVQANK QLHHQAVDSP ARSSMTATTA ANSNSNSSRD 60
61 DSTIVGLHYK IGKKIGEGSF GVLFEGTNMI NGVPVAIKFE PRKTEAPQLR D
|
|
Region B: Residues: [128-143] |
1 11 21 31 41 51
| | | | | |
1 AYYFGQEGLH NILVID
|
| Detection Method: |  |
| Confidence: | 1277.0 |
| Match: | 1csn__ |
| Description: | Casein kinase-1, CK1 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| phosphotransferase activity, alcohol group as acceptor | 5.49988294224815 | bayes_pls_golite062009 |
| protein kinase activity | 5.4586557943719 | bayes_pls_golite062009 |
| kinase activity | 5.3287080791198 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 4.96052051118534 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 4.46381887831481 | bayes_pls_golite062009 |
| transferase activity | 3.97138602499442 | bayes_pls_golite062009 |
| protein tyrosine kinase activity | 2.8153155526437 | bayes_pls_golite062009 |
| binding | 2.74863538127007 | bayes_pls_golite062009 |
| transmembrane receptor activity | 2.59526003830791 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 2.54265774272269 | bayes_pls_golite062009 |
| molecular transducer activity | 2.40586892801446 | bayes_pls_golite062009 |
| signal transducer activity | 2.40586892801446 | bayes_pls_golite062009 |
| receptor activity | 2.39311927684508 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine kinase activity | 2.16831387024372 | bayes_pls_golite062009 |
| receptor signaling protein activity | 2.10379226653669 | bayes_pls_golite062009 |
| ATP binding | 1.97600611746091 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 1.93596671856664 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 1.90928021591891 | bayes_pls_golite062009 |
| receptor signaling protein serine/threonine kinase activity | 1.81249386965144 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 1.65732943334212 | bayes_pls_golite062009 |
| ribonucleotide binding | 1.65726906484847 | bayes_pls_golite062009 |
| purine nucleotide binding | 1.63763394711025 | bayes_pls_golite062009 |
| nucleotide binding | 1.63195828048121 | bayes_pls_golite062009 |
| protein binding | 1.22565748038754 | bayes_pls_golite062009 |
| catalytic activity | 1.21655087018101 | bayes_pls_golite062009 |
| transporter activity | 1.11833481501707 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.97575992765505 | bayes_pls_golite062009 |
| growth factor binding | 0.86076618871384 | bayes_pls_golite062009 |
| nucleic acid binding | 0.794058505655489 | bayes_pls_golite062009 |
| transcription regulator activity | 0.775404673285876 | bayes_pls_golite062009 |
| DNA binding | 0.714163549867672 | bayes_pls_golite062009 |
| transcription factor activity | 0.563262875317016 | bayes_pls_golite062009 |
| peptidase activity | 0.540289770145252 | bayes_pls_golite062009 |
| cyclin-dependent protein kinase activity | 0.499492353295369 | bayes_pls_golite062009 |
| protein serine/threonine/tyrosine kinase activity | 0.48345772948903 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.451090007290896 | bayes_pls_golite062009 |
| protein kinase C activity | 0.41587987561486 | bayes_pls_golite062009 |
| magnesium ion binding | 0.393328812780268 | bayes_pls_golite062009 |
| MAP kinase kinase kinase activity | 0.37115026509016 | bayes_pls_golite062009 |
| MAP kinase kinase activity | 0.35402045013148 | bayes_pls_golite062009 |
| kinase binding | 0.26752427107238 | bayes_pls_golite062009 |
| peptidase activity, acting on L-amino acid peptides | 0.265003282584135 | bayes_pls_golite062009 |
| MAP kinase activity | 0.26024936404169 | bayes_pls_golite062009 |
| protein complex binding | 0.239339759110451 | bayes_pls_golite062009 |
| transforming growth factor beta receptor activity | 0.20643152368029 | bayes_pls_golite062009 |
| transmembrane receptor protein serine/threonine kinase activity | 0.20643152368029 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.205652638854091 | bayes_pls_golite062009 |
| receptor binding | 0.197402253061255 | bayes_pls_golite062009 |
| protein kinase binding | 0.00674998152095019 | bayes_pls_golite062009 |
|
Region A: Residues: [112-127] |
1 11 21 31 41 51
| | | | | |
1 EYKTYKILNG TPNIPY
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Region B: Residues: [144-149] |
1 11 21 31 41 51
| | | | | |
1 LLGPSL
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Region C: Residues: [174-226] |
1 11 21 31 41 51
| | | | | |
1 TLIEDLHAHD LIYRDIKPDN FLIGRPGQPD ANNIHLIDFG MAKQYRDPKT KQH
|
| Detection Method: | |
| Confidence: | 1277.0 |
| Match: | 1csn__ |
| Description: | Casein kinase-1, CK1 |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [150-173] |
1 11 21 31 41 51
| | | | | |
1 EDLFDWCGRK FSVKTVVQVA VQMI
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Region B: Residues: [227-416] |
1 11 21 31 41 51
| | | | | |
1 IPYREKKSLS GTARYMSINT HLGREQSRRD DMEALGHVFF YFLRGHLPWQ GLKAPNNKQK 60
61 YEKIGEKKRS TNVYDLAQGL PVQFGRYLEI VRSLSFEECP DYEGYRKLLL SVLDDLGETA 120
121 DGQYDWMKLN DGRGWDLNIN KKPNLHGYGH PNPPNEKSRK HRNKQLQMQQ LQMQQLQQQQ 180
181 QQQQYAQKTE
|
| Detection Method: | |
| Confidence: | 1277.0 |
| Match: | 1csn__ |
| Description: | Casein kinase-1, CK1 |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [417-538] |
1 11 21 31 41 51
| | | | | |
1 ADMRNSQYKP KLDPTSYEAY QHQTQQKYLQ EQQKRQQQQK LQEQQLQEQQ LQQQQQQQQQ 60
61 LRATGQPPSQ PQAQTQSQQF GARYQPQQQP SAALRTPEQH PNDDNSSLAA SHKGFFQKLG 120
121 CC
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.633 | a.1.1 | Globin-like |
| View | Download | 0.537 | a.47.2 | t-snare proteins |
| View | Download | 0.662 | a.66.1 | Transducin (alpha subunit), insertion domain |
| View | Download | 0.604 | a.24.10 | Histidine-containing phosphotransfer domain, HPT domain |
| View | Download | 0.598 | c.54.1 | IIA domain of mannose transporter, IIA-Man |
| View | Download | 0.460 | a.47.2 | t-snare proteins |
| View | Download | 0.452 | a.24.4 | Hemerythrin |
| View | Download | 0.435 | a.72.1 | Functional domain of the splicing factor Prp18 |
| View | Download | 0.426 | a.60.6 | DNA polymerase beta, N-terminal domain-like |
| View | Download | 0.425 | f.34.1 | Mechanosensitive channel protein MscS (YggB), transmembrane region |
| View | Download | 0.422 | a.25.2 | Thermoplasma ferritin-like 4-helical bundle |
| View | Download | 0.417 | a.25.1 | Ferritin-like |
| View | Download | 0.381 | f.34.1 | Mechanosensitive channel protein MscS (YggB), transmembrane region |
| View | Download | 0.380 | a.47.2 | t-snare proteins |
| View | Download | 0.372 | a.24.3 | Cytochromes |
| View | Download | 0.369 | i.11.1 | Computational models partly based on NMR data |
| View | Download | 0.367 | a.25.1 | Ferritin-like |
| View | Download | 0.360 | a.7.7 | BAG domain |
| View | Download | 0.360 | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.347 | b.40.4 | Nucleic acid-binding proteins |
| View | Download | 0.342 | a.25.1 | Ferritin-like |
| View | Download | 0.342 | a.47.2 | t-snare proteins |
| View | Download | 0.341 | a.47.2 | t-snare proteins |
| View | Download | 0.340 | a.24.16 | Nucleotidyltransferase substrate binding subunit/domain |
| View | Download | 0.339 | a.24.4 | Hemerythrin |
| View | Download | 0.333 | a.24.16 | Nucleotidyltransferase substrate binding subunit/domain |
| View | Download | 0.325 | a.24.16 | Nucleotidyltransferase substrate binding subunit/domain |
| View | Download | 0.323 | a.7.5 | Tubulin chaperone cofactor A |
| View | Download | 0.321 | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.317 | i.11.1 | Computational models partly based on NMR data |
| View | Download | 0.313 | a.24.16 | Nucleotidyltransferase substrate binding subunit/domain |
| View | Download | 0.311 | a.26.1 | 4-helical cytokines |
| View | Download | 0.309 | c.26.2 | Adenine nucleotide alpha hydrolases-like |
| View | Download | 0.303 | a.182.1 | GatB/YqeY domain |
| View | Download | 0.302 | a.7.2 | Enzyme IIa from lactose specific PTS, IIa-lac |
| View | Download | 0.299 | a.7.2 | Enzyme IIa from lactose specific PTS, IIa-lac |
| View | Download | 0.298 | c.25.1 | Ferredoxin reductase-like, C-terminal NADP-linked domain |
| View | Download | 0.289 | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.288 | d.58.42 | N-utilization substance G protein NusG, N-terminal domain |
| View | Download | 0.288 | a.25.1 | Ferritin-like |
| View | Download | 0.284 | a.118.8 | TPR-like |
| View | Download | 0.284 | a.63.1 | Apolipophorin-III |
| View | Download | 0.282 | a.1.1 | Globin-like |
| View | Download | 0.278 | a.133.1 | Phospholipase A2, PLA2 |
| View | Download | 0.276 | a.26.1 | 4-helical cytokines |
| View | Download | 0.272 | d.110.4 | SNARE-like |
| View | Download | 0.271 | a.77.1 | DEATH domain |
| View | Download | 0.268 | a.24.16 | Nucleotidyltransferase substrate binding subunit/domain |
| View | Download | 0.266 | a.25.2 | Thermoplasma ferritin-like 4-helical bundle |
| View | Download | 0.265 | a.24.16 | Nucleotidyltransferase substrate binding subunit/domain |
| View | Download | 0.265 | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.264 | a.1.1 | Globin-like |
| View | Download | 0.259 | a.74.1 | Cyclin-like |
| View | Download | 0.257 | a.72.1 | Functional domain of the splicing factor Prp18 |
| View | Download | 0.255 | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.249 | a.7.5 | Tubulin chaperone cofactor A |
| View | Download | 0.248 | a.7.6 | Ribosomal protein S20 |
| View | Download | 0.247 | a.7.3 | Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain |
| View | Download | 0.245 | a.24.10 | Histidine-containing phosphotransfer domain, HPT domain |
| View | Download | 0.245 | a.7.2 | Enzyme IIa from lactose specific PTS, IIa-lac |
| View | Download | 0.245 | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.242 | d.122.1 | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase |
| View | Download | 0.240 | a.25.1 | Ferritin-like |
| View | Download | 0.236 | a.24.16 | Nucleotidyltransferase substrate binding subunit/domain |
| View | Download | 0.232 | a.7.6 | Ribosomal protein S20 |
| View | Download | 0.227 | a.25.1 | Ferritin-like |
| View | Download | 0.226 | a.26.1 | 4-helical cytokines |
| View | Download | 0.225 | a.24.16 | Nucleotidyltransferase substrate binding subunit/domain |
| View | Download | 0.225 | a.7.6 | Ribosomal protein S20 |
| View | Download | 0.224 | a.26.1 | 4-helical cytokines |
| View | Download | 0.222 | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.221 | a.2.8 | Eukaryotic DNA topoisomerase I, dispensable insert domain |
| View | Download | 0.216 | a.1.1 | Globin-like |
| View | Download | 0.216 | a.1.1 | Globin-like |
| View | Download | 0.214 | a.25.1 | Ferritin-like |
| View | Download | 0.213 | a.74.1 | Cyclin-like |
| View | Download | 0.210 | a.25.2 | Thermoplasma ferritin-like 4-helical bundle |
| View | Download | 0.209 | a.7.7 | BAG domain |
| View | Download | 0.208 | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.207 | c.26.2 | Adenine nucleotide alpha hydrolases-like |
| View | Download | 0.206 | a.182.1 | GatB/YqeY domain |
| View | Download | 0.205 | a.91.1 | Regulator of G-protein signalling, RGS |
| View | Download | 0.205 | a.7.3 | Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain |
| View | Download | 0.204 | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.204 | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.203 | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.203 | a.2.3 | Chaperone J-domain |
