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View Structure Prediction Details

Protein: CCDS11659.1_1
Organism: Chlorocebus aethiops
Length: 614 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CCDS11659.1_1.

Description E-value Query
Range		 Subject
Range
DDX5_MOUSE - Probable ATP-dependent RNA helicase DDX5 OS=Mus musculus GN=Ddx5 PE=1 SV=1
 0.0 [1..614] [1..614]
gi|74354729 - gi|74354729|gb|AAI03319.1| DDX5 protein [Bos taurus]
 0.0 [1..614] [58..671]
gi|30584123, gi|... - gi|60653929|gb|AAX29657.1| DEAD box polypeptide 5 [synthetic construct], gi|30584123|gb|AAP36310.1| ...
 0.0 [1..614] [1..614]
DDX5_MACFA - Probable ATP-dependent RNA helicase DDX5 OS=Macaca fascicularis GN=DDX5 PE=2 SV=1
 0.0 [1..614] [1..614]
DDX5_PONAB - Probable ATP-dependent RNA helicase DDX5 OS=Pongo abelii GN=DDX5 PE=2 SV=1
DDX5_PONPY - Probable ATP-dependent RNA helicase DDX5 - Pongo pygmaeus (Orangutan)
 0.0 [1..614] [1..614]
gi|73965229 - gi|73965229|ref|XP_861744.1| PREDICTED: similar to Probable RNA-dependent helicase p68 (DEAD-box pro...
 0.0 [1..614] [1..616]

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Predicted Domain #1
Region A:
Residues: [1-94] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGYSSDRDR GRDRGFGAPR FGGSRAGPLS GKKFGNPGEK LVKKKWNLDE LPKFEKNFYQ  60
   61 EHPDLARRTA QEVETYRRSK EITVRGHNCP KPVL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 86.30103
Match: 2db3A
Description: No description for 2db3A was found.

Predicted Domain #2
Region A:
Residues: [95-614] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NFYEANFPAN VMDVIARQNF TEPTAIQAQG WPVALSGLDM VGVAQTGSGK TLSYLLPAIV  60
   61 HINHQPFLER GDGPICLVLA PTRELAQQVQ QVAAEYCRAC RLKSTCIYGG APKGPQIRDL 120
  121 ERGVEICIAT PGRLIDFLEC GKTNLRRTTY LVLDEADRML DMGFEPQIRK IVDQIRPDRQ 180
  181 TLMWSATWPK EVRQLAEDFL KDYIHINIGA LELSANHNIL QIVDVCHDVE KDEKLIRLME 240
  241 EIMSEKENKT IVFVETKRRC DELTRKMRRD GWPAMGIHGD KSQQERDWVL NEFKHGKAPI 300
  301 LIATDVASRG LDVEDVKFVI NYDYPNSSED YIHRIGRTAR STKTGTAYTF FTPNNIKQVS 360
  361 DLISVLREAN QAINPKLLQL VEDRGSGRSR GRGGMKDDRR DRYSAGKRGG FNTFRDRENY 420
  421 DRGYSSLLKR DFGAKTQNGV YSAANYTNGS FGSNFVSAGI QTSFRTGNPT GTYQNGYDST 480
  481 QQYGSNVPNM HNGMNQQAYA YPATAAAPMI GYPMPTGYSQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 52.69897
Match: 1oywA
Description: Structure of the RecQ Catalytic Core
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
translation initiation factor activity 7.79457008386475 bayes_pls_golite062009
translation factor activity, nucleic acid binding 4.98637553020315 bayes_pls_golite062009
translation regulator activity 4.94658029227343 bayes_pls_golite062009
4.704140727858 bayes_pls_golite062009
structural constituent of ribosome 4.56509805974548 bayes_pls_golite062009
structural molecule activity 3.58406348799895 bayes_pls_golite062009
transporter activity 3.10463051760206 bayes_pls_golite062009
transmembrane transporter activity 2.95886887664984 bayes_pls_golite062009
nucleoside-triphosphatase activity 2.95079405147356 bayes_pls_golite062009
pyrophosphatase activity 2.87427509025394 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 2.85499564954033 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 2.85178667290149 bayes_pls_golite062009
motor activity 2.79327761685782 bayes_pls_golite062009
microtubule motor activity 2.74365461017633 bayes_pls_golite062009
binding 2.64537357529343 bayes_pls_golite062009
primary active transmembrane transporter activity 2.61775212528604 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 2.61467977505707 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 2.57552435627908 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 2.57107347424517 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 2.57054427875021 bayes_pls_golite062009
nucleic acid binding 2.51683451033161 bayes_pls_golite062009
active transmembrane transporter activity 2.50494515048649 bayes_pls_golite062009
translation release factor activity 2.49148102494524 bayes_pls_golite062009
translation termination factor activity 2.46464632547226 bayes_pls_golite062009
ATPase activity, coupled 2.43862163407966 bayes_pls_golite062009
ATPase activity 2.39535714892224 bayes_pls_golite062009
RNA binding 2.29590582680214 bayes_pls_golite062009
RNA cap binding 2.17871969124431 bayes_pls_golite062009
DNA binding 2.12258000781149 bayes_pls_golite062009
transcription regulator activity 2.09345198747025 bayes_pls_golite062009
substrate-specific transporter activity 1.91091452720653 bayes_pls_golite062009
helicase activity 1.70242731830224 bayes_pls_golite062009
hydrolase activity 1.57549510726226 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 1.56325751172863 bayes_pls_golite062009
protein-DNA loading ATPase activity 1.54436515966471 bayes_pls_golite062009
DNA clamp loader activity 1.51134988628578 bayes_pls_golite062009
RNA helicase activity 1.42791449104435 bayes_pls_golite062009
cytoskeletal protein binding 1.40488517180956 bayes_pls_golite062009
RNA-dependent ATPase activity 1.39335733374328 bayes_pls_golite062009
ATP-dependent RNA helicase activity 1.36724390116598 bayes_pls_golite062009
protein transporter activity 1.25342367751911 bayes_pls_golite062009
protein binding 1.22129154759482 bayes_pls_golite062009
DNA-dependent ATPase activity 1.2155186842031 bayes_pls_golite062009
ATP-dependent helicase activity 1.19311444180077 bayes_pls_golite062009
purine NTP-dependent helicase activity 1.19311444180077 bayes_pls_golite062009
catalytic activity 1.00104173493322 bayes_pls_golite062009
tubulin binding 0.979946830272106 bayes_pls_golite062009
ion transmembrane transporter activity 0.977237423302079 bayes_pls_golite062009
DNA-directed DNA polymerase activity 0.971476020912368 bayes_pls_golite062009
purine nucleotide binding 0.929901285538132 bayes_pls_golite062009
DNA polymerase activity 0.928091843881235 bayes_pls_golite062009
nucleotide binding 0.922442819194247 bayes_pls_golite062009
purine ribonucleotide binding 0.920987930180051 bayes_pls_golite062009
ribonucleotide binding 0.920926158369519 bayes_pls_golite062009
microtubule binding 0.907162506177187 bayes_pls_golite062009
transcription activator activity 0.889929694023098 bayes_pls_golite062009
transcription factor activity 0.887108427603557 bayes_pls_golite062009
actin binding 0.883285269827407 bayes_pls_golite062009
structure-specific DNA binding 0.782430219754236 bayes_pls_golite062009
mRNA binding 0.76699944561918 bayes_pls_golite062009
DNA helicase activity 0.72881469450553 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.652333406433794 bayes_pls_golite062009
double-stranded DNA binding 0.6071273686445 bayes_pls_golite062009
ATP-dependent DNA helicase activity 0.5886142102548 bayes_pls_golite062009
cation transmembrane transporter activity 0.557919489256916 bayes_pls_golite062009
sequence-specific DNA binding 0.543891899378373 bayes_pls_golite062009
GTPase activity 0.437665353870877 bayes_pls_golite062009
snRNA binding 0.418985924846052 bayes_pls_golite062009
ATP binding 0.41092997612902 bayes_pls_golite062009
adenyl ribonucleotide binding 0.385813421701492 bayes_pls_golite062009
adenyl nucleotide binding 0.377870145186619 bayes_pls_golite062009
guanyl nucleotide binding 0.296406132096546 bayes_pls_golite062009
GTP binding 0.295705904888768 bayes_pls_golite062009
guanyl ribonucleotide binding 0.29028316917561 bayes_pls_golite062009
molecular transducer activity 0.286367085584159 bayes_pls_golite062009
signal transducer activity 0.286367085584159 bayes_pls_golite062009
RNA polymerase II transcription factor activity, enhancer binding 0.25390390749265 bayes_pls_golite062009
hydrogen ion transporting ATP synthase activity, rotational mechanism 0.213018989352421 bayes_pls_golite062009
DNA strand annealing activity 0.201168339081339 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 0.123304946374679 bayes_pls_golite062009
microfilament motor activity 0.10236059675512 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 0.0856082199488197 bayes_pls_golite062009
metal ion transmembrane transporter activity 0.0775601177068852 bayes_pls_golite062009
protein transmembrane transporter activity 0.0378638259240902 bayes_pls_golite062009
signal sequence binding 6.53725193420218E-4 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle