| Protein: | PDPK1_ARATH |
| Organism: | Arabidopsis thaliana |
| Length: | 491 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PDPK1_ARATH.
| Description | E-value | Query Range |
Subject Range |
|
|
435.0 | [0..4] | [491..1] |
|
Region A: Residues: [1-360] |
1 11 21 31 41 51
| | | | | |
1 MLAMEKEFDS KLVLQGNSSN GANVSRSKSF SFKAPQENFT SHDFEFGKIY GVGSYSKVVR 60
61 AKKKETGTVY ALKIMDKKFI TKENKTAYVK LERIVLDQLE HPGIIKLYFT FQDTSSLYMA 120
121 LESCEGGELF DQITRKGRLS EDEARFYTAE VVDALEYIHS MGLIHRDIKP ENLLLTSDGH 180
181 IKIADFGSVK PMQDSQITVL PNAASDDKAC TFVGTAAYVP PEVLNSSPAT FGNDLWALGC 240
241 TLYQMLSGTS PFKDASEWLI FQRIIARDIK FPNHFSEAAR DLIDRLLDTE PSRRPGAGSE 300
301 GYVALKRHPF FNGVDWKNLR SQTPPKLAPD PASQTASPER DDTHGSPWNL THIGDSLATQ 360
361
|
| Detection Method: |  |
| Confidence: | 69.522879 |
| Match: | 1okyA |
| Description: | Structure of human PDK1 kinase domain in complex with staurosporine |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| phosphotransferase activity, alcohol group as acceptor | 5.49988294224815 | bayes_pls_golite062009 |
| protein kinase activity | 5.4586557943719 | bayes_pls_golite062009 |
| kinase activity | 5.3287080791198 | bayes_pls_golite062009 |
| cyclic nucleotide-dependent protein kinase activity | 4.97855712164511 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 4.96052051118534 | bayes_pls_golite062009 |
| cAMP-dependent protein kinase activity | 4.66277812893755 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 4.46381887831481 | bayes_pls_golite062009 |
| transferase activity | 3.97138602499442 | bayes_pls_golite062009 |
| protein tyrosine kinase activity | 2.8153155526437 | bayes_pls_golite062009 |
| binding | 2.74863538127007 | bayes_pls_golite062009 |
| transmembrane receptor activity | 2.59526003830791 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 2.54265774272269 | bayes_pls_golite062009 |
| signal transducer activity | 2.40586892801446 | bayes_pls_golite062009 |
| molecular transducer activity | 2.40586892801446 | bayes_pls_golite062009 |
| receptor activity | 2.39311927684508 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine kinase activity | 2.16831387024372 | bayes_pls_golite062009 |
| receptor signaling protein activity | 2.10379226653669 | bayes_pls_golite062009 |
| ATP binding | 1.97600611746091 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 1.93596671856664 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 1.90928021591891 | bayes_pls_golite062009 |
| receptor signaling protein serine/threonine kinase activity | 1.81249386965144 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 1.65732943334212 | bayes_pls_golite062009 |
| ribonucleotide binding | 1.65726906484847 | bayes_pls_golite062009 |
| purine nucleotide binding | 1.63763394711025 | bayes_pls_golite062009 |
| nucleotide binding | 1.63195828048121 | bayes_pls_golite062009 |
| insulin receptor substrate binding | 1.62657794525303 | bayes_pls_golite062009 |
| kinase binding | 1.26086833316556 | bayes_pls_golite062009 |
| phosphoinositide 3-kinase binding | 1.25285260301349 | bayes_pls_golite062009 |
| protein binding | 1.22565748038754 | bayes_pls_golite062009 |
| catalytic activity | 1.21655087018101 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 1.1208666000428 | bayes_pls_golite062009 |
| transporter activity | 1.11833481501707 | bayes_pls_golite062009 |
| protein kinase binding | 1.06030596516506 | bayes_pls_golite062009 |
| actin binding | 1.00749371062134 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.97575992765505 | bayes_pls_golite062009 |
| growth factor binding | 0.86076618871384 | bayes_pls_golite062009 |
| MAP kinase activity | 0.81943579965027 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.705905455086486 | bayes_pls_golite062009 |
| nucleic acid binding | 0.655396214040669 | bayes_pls_golite062009 |
| transcription regulator activity | 0.631882811427766 | bayes_pls_golite062009 |
| DNA binding | 0.599969415455862 | bayes_pls_golite062009 |
| cyclin-dependent protein kinase activity | 0.499492353295369 | bayes_pls_golite062009 |
| tubulin binding | 0.488928950975855 | bayes_pls_golite062009 |
| protein serine/threonine/tyrosine kinase activity | 0.48345772948903 | bayes_pls_golite062009 |
| enzyme binding | 0.46284745266176 | bayes_pls_golite062009 |
| transcription factor activity | 0.457173041568166 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.450699332958421 | bayes_pls_golite062009 |
| magnesium ion binding | 0.393328812780268 | bayes_pls_golite062009 |
| MAP kinase kinase kinase activity | 0.37115026509016 | bayes_pls_golite062009 |
| MAP kinase kinase activity | 0.35402045013148 | bayes_pls_golite062009 |
| protein complex binding | 0.239339759110451 | bayes_pls_golite062009 |
| insulin receptor activity | 0.237134032032089 | bayes_pls_golite062009 |
| SH2 domain binding | 0.226760162354251 | bayes_pls_golite062009 |
| transforming growth factor beta receptor activity | 0.20643152368029 | bayes_pls_golite062009 |
| transmembrane receptor protein serine/threonine kinase activity | 0.20643152368029 | bayes_pls_golite062009 |
| receptor binding | 0.197402253061255 | bayes_pls_golite062009 |
| microtubule binding | 0.196718452862042 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 0.148194101970458 | bayes_pls_golite062009 |
| collagen binding | 0.126438719981406 | bayes_pls_golite062009 |
| peptide binding | 0.118578378753757 | bayes_pls_golite062009 |
| transforming growth factor beta receptor activity, type I | 0.0506751594607393 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.0040394359628233 | bayes_pls_golite062009 |
|
Region A: Residues: [361-491] |
1 11 21 31 41 51
| | | | | |
1 NEGHSAPPTS SESSGSITRL ASIDSFDSRW QQFLEPGESV LMISAVKKLQ KITSKKVQLI 60
61 LTNKPKLIYV DPSKLVVKGN IIWSDNSNDL NVVVTSPSHF KICTPKKVLS FEDAKQRASV 120
121 WKKAIETLQN R
|
| Detection Method: | |
| Confidence: | 28.0 |
| Match: | 1w1dA |
| Description: | Crystal Structure of the PDK1 Pleckstrin Homology (PH) domain bound to Inositol (1,3,4,5)-tetrakisphosphate |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 3.29080729281876 | bayes_pls_golite062009 |
| actin binding | 2.85686087329077 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 2.48216092627697 | bayes_pls_golite062009 |
| protein binding | 2.12168271674167 | bayes_pls_golite062009 |
| signal transducer activity | 1.55319485371003 | bayes_pls_golite062009 |
| molecular transducer activity | 1.55319485371003 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 1.53043443218632 | bayes_pls_golite062009 |
| insulin receptor binding | 1.51333207678681 | bayes_pls_golite062009 |
| kinase activity | 1.49733072352288 | bayes_pls_golite062009 |
| SH2 domain binding | 1.41526564231882 | bayes_pls_golite062009 |
| cell adhesion molecule binding | 1.3855488465667 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.36365892826676 | bayes_pls_golite062009 |
| protein kinase activity | 1.34246406302496 | bayes_pls_golite062009 |
| phosphoinositide 3-kinase binding | 1.30262007369665 | bayes_pls_golite062009 |
| transporter activity | 1.28986800087234 | bayes_pls_golite062009 |
| receptor binding | 1.28569939553368 | bayes_pls_golite062009 |
| insulin-like growth factor receptor binding | 1.19081327922916 | bayes_pls_golite062009 |
| actin filament binding | 1.19004539998398 | bayes_pls_golite062009 |
| receptor activity | 1.1755016270537 | bayes_pls_golite062009 |
| enzyme binding | 1.17212675145623 | bayes_pls_golite062009 |
| transcription regulator activity | 1.17024030272587 | bayes_pls_golite062009 |
| transmembrane receptor activity | 1.1152029796159 | bayes_pls_golite062009 |
| phospholipid binding | 1.09683218092034 | bayes_pls_golite062009 |
| transferase activity | 1.05502123133116 | bayes_pls_golite062009 |
| nucleic acid binding | 1.04786326338998 | bayes_pls_golite062009 |
| DNA binding | 1.02624078384285 | bayes_pls_golite062009 |
| receptor signaling protein activity | 1.00400540041137 | bayes_pls_golite062009 |
| kinase binding | 0.961706066143 | bayes_pls_golite062009 |
| protein domain specific binding | 0.90578029954417 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.79883446648737 | bayes_pls_golite062009 |
| phosphoinositide binding | 0.71817045430443 | bayes_pls_golite062009 |
| protein kinase binding | 0.67284191028382 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.611829373978789 | bayes_pls_golite062009 |
| protein complex binding | 0.55916857709427 | bayes_pls_golite062009 |
| GTPase regulator activity | 0.355387992614734 | bayes_pls_golite062009 |
| nucleoside-triphosphatase regulator activity | 0.335498703113274 | bayes_pls_golite062009 |
| structural molecule activity | 0.320527491838187 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine kinase signaling protein activity | 0.28468123649303 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 0.261970566755445 | bayes_pls_golite062009 |
| enzyme regulator activity | 0.189879136353541 | bayes_pls_golite062009 |
| lipid binding | 0.179561240451969 | bayes_pls_golite062009 |
| pyrophosphatase activity | 0.0611639610381174 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides | 0.0524559849408587 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 0.0498422520006935 | bayes_pls_golite062009 |
