YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|224552853
Organism:	Bacillus anthracis str. 'Ames Ancestor'
Length:	264 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|224552853.

Description	E-value	Query Range	Subject Range
gi\|52144879, gi\|... - gi\|52144879\|ref\|YP_081948.1\| amino acid ABC transporter, substrate-binding protein [Bacillus cereus ...	3.0E-57	[1..264]	[1..264]
gi\|218895476, gi... - gi\|218895476\|ref\|YP_002443887.1\| putative amino acid ABC transporter, amino acid-binding protein [Ba... gi\|74492926, gi\|... - gi\|75759591\|ref\|ZP_00739678.1\| Cystine-binding protein [Bacillus thuringiensis serovar israelensis A... gi\|228860518, gi... - gi\|228899077\|ref\|ZP_04063349.1\| Amino acid ABC transporter, solute binding protein [Bacillus thuring...	2.0E-56	[1..264]	[1..264]
gi\|89204734, gi\|... - gi\|89204734\|ref\|ZP_01183310.1\| extracellular solute-binding protein, family 3 [Bacillus weihenstepha... gi\|228652100, gi... - gi\|229131356\|ref\|ZP_04260256.1\| Amino acid ABC transporter, solute binding protein [Bacillus cereus ... gi\|229170388, gi... - gi\|229170388\|ref\|ZP_04298061.1\| Amino acid ABC transporter, solute binding protein [Bacillus cereus ...	2.0E-56	[1..264]	[1..264]
gi\|42779548, gi\|... - gi\|42779548\|ref\|NP_976795.1\| amino acid ABC transporter, amino acid-binding protein [Bacillus cereus...	2.0E-56	[1..264]	[1..264]
gi\|228776095, gi... - gi\|228983610\|ref\|ZP_04143814.1\| Amino acid ABC transporter, solute binding protein [Bacillus thuring... gi\|47553934, gi\|... - gi\|47569426\|ref\|ZP_00240108.1\| amino acid ABC transporter, periplasmic amino acid-binding protein [B...	4.0E-56	[1..264]	[1..264]
gi\|30018610, gi\|... - gi\|30018610\|ref\|NP_830241.1\| cystine-binding protein [Bacillus cereus ATCC 14579], gi\|29894151\|gb\|AA... gi\|228675425, gi... - gi\|229108025\|ref\|ZP_04237651.1\| Amino acid ABC transporter, solute binding protein [Bacillus cereus ... gi\|229042256, gi... - gi\|229042256\|ref\|ZP_04190008.1\| Amino acid ABC transporter, solute binding protein [Bacillus cereus ... gi\|229143145, gi... - gi\|229143145\|ref\|ZP_04271577.1\| Amino acid ABC transporter, solute binding protein [Bacillus cereus ... gi\|228657510, gi... - gi\|229125852\|ref\|ZP_04254877.1\| Amino acid ABC transporter, solute binding protein [Bacillus cereus ...	1.0E-54	[1..264]	[1..264]
gi\|238717579, gi... - gi\|77961132\|ref\|ZP_00824978.1\| COG0834: ABC-type amino acid transport/signal transduction systems, p...	1.0E-54	[2..258]	[13..272]
gi\|77957941 - gi\|77957941\|ref\|ZP_00821984.1\| COG0834: ABC-type amino acid transport/signal transduction systems, p...	3.0E-54	[2..258]	[7..266]
gi\|77979904 - gi\|77979904\|ref\|ZP_00835320.1\| COG0834: ABC-type amino acid transport/signal transduction systems, p...	6.0E-54	[2..258]	[13..272]
gi\|77975692 - gi\|77975692\|ref\|ZP_00831226.1\| COG0834: ABC-type amino acid transport/signal transduction systems, p...	8.0E-54	[2..258]	[7..266]

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Predicted Domain #1

Region A:
Residues: [1-264]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKRKLLTIVA SITLCTSFIL GACSKESATT SSNGKKEFRY AMSGLYKPFN YKENDGKLVG  60
   61 FDVEIGEALA KKMNMKPTPI TNPWETLIQG LKAKKYDVIL GSMAITEERL KAVNFSNPYY 120
  121 RSGAQIFVAK KNTSISSPED LKGKKIGVVK ASTFKDLVAK HTDQITEYDS DITALMDLEP 180
  181 GRIDAVITDQ MVGLRMIKEG KSNIKEAGKP LNLDEMGIAI RKDDKEMVEK VNKALDEIIK 240
  241 DGTYEKISKK WFGRNILGEE ENTK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	44.69897
Match:	1hpbP
Description:	Histidine-binding protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ATPase activity, coupled to transmembrane movement of substances	5.10369591387353	bayes_pls_golite062009
ATPase activity, coupled to movement of substances	5.10318083615538	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	5.10318083615538	bayes_pls_golite062009
active transmembrane transporter activity	5.08926597039825	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	5.08835444171664	bayes_pls_golite062009
primary active transmembrane transporter activity	5.0778580713249	bayes_pls_golite062009
ATPase activity, coupled	4.39934929410381	bayes_pls_golite062009
transporter activity	4.36277471796561	bayes_pls_golite062009
amine transmembrane transporter activity	4.06067446901213	bayes_pls_golite062009
transmembrane transporter activity	4.05122336499684	bayes_pls_golite062009
ATPase activity	4.04125376161476	bayes_pls_golite062009
organic acid transmembrane transporter activity	4.00950407295699	bayes_pls_golite062009
carboxylic acid transmembrane transporter activity	4.00681079961203	bayes_pls_golite062009
polyamine transmembrane transporter activity	3.56664180812545	bayes_pls_golite062009
substrate-specific transporter activity	3.47889550245964	bayes_pls_golite062009
anion transmembrane-transporting ATPase activity	3.25040168593981	bayes_pls_golite062009
inorganic anion transmembrane transporter activity	3.16446457499691	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	2.87472545473244	bayes_pls_golite062009
polyamine-transporting ATPase activity	2.84609722276735	bayes_pls_golite062009
amino acid binding	2.79295963421917	bayes_pls_golite062009
anion transmembrane transporter activity	2.77148301796671	bayes_pls_golite062009
peptide transporter activity	2.75577307623285	bayes_pls_golite062009
molybdate transmembrane-transporting ATPase activity	2.58578176144479	bayes_pls_golite062009
molybdate ion transmembrane transporter activity	2.58578176144479	bayes_pls_golite062009
amino acid transmembrane transporter activity	2.47628874886983	bayes_pls_golite062009
hydrolase activity	2.41680852416007	bayes_pls_golite062009
amine binding	2.37157043664258	bayes_pls_golite062009
polyamine binding	2.27573366139794	bayes_pls_golite062009
oligopeptide transporter activity	1.91036692266394	bayes_pls_golite062009
ion transmembrane transporter activity	1.70693655091183	bayes_pls_golite062009
nucleoside-triphosphatase activity	1.70643051049474	bayes_pls_golite062009
pyrophosphatase activity	1.65646853917778	bayes_pls_golite062009
amino acid-transporting ATPase activity	1.65232476690022	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	1.63520066802961	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	1.6341518946909	bayes_pls_golite062009
amine-transporting ATPase activity	1.59812090922796	bayes_pls_golite062009
binding	1.54172013140566	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions	0.99134553005852	bayes_pls_golite062009
neutral amino acid transmembrane transporter activity	0.36821604053554	bayes_pls_golite062009
L-amino acid transmembrane transporter activity	0.29324308961663	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	0.230402103022499	bayes_pls_golite062009
putrescine transmembrane transporter activity	0.212254208912362	bayes_pls_golite062009
catalytic activity	0.131708946574025	bayes_pls_golite062009
cation transmembrane transporter activity	0.119916745111395	bayes_pls_golite062009
sulfate transmembrane-transporting ATPase activity	0.0940079640524907	bayes_pls_golite062009
transition metal ion transmembrane transporter activity	0.00844917716785965	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: