| From Publication: | Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054 |
| Notes: | Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.825752537142] |
| Complex Size: | 2 proteins |
| Protein |
GO Cellular Component | GO Biological Process | GO Molecular Function |
| MCM6 |
|
|
|
| RFC1 |
|
|
|
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
| GO Term |
P-value |
A |
B |
I |
T |
| chromosomal part | 1.413E-3 | 2 | 237 | 2 | 6292 |
| chromosome | 1.8898E-3 | 2 | 274 | 2 | 6292 |
| MCM complex | 2.224E-3 | 2 | 7 | 1 | 6292 |
| DNA replication factor C complex | 3.4937E-3 | 2 | 11 | 1 | 6292 |
| pre-replicative complex | 5.0798E-3 | 2 | 16 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
| GO Term |
P-value |
A |
B |
I |
T |
| DNA-dependent DNA replication | 1.678E-4 | 2 | 82 | 2 | 6292 |
| DNA replication | 3.791E-4 | 2 | 123 | 2 | 6292 |
| DNA unwinding involved in replication | 4.4455E-3 | 2 | 14 | 1 | 6292 |
| leading strand elongation | 4.7627E-3 | 2 | 15 | 1 | 6292 |
| DNA geometric change | 6.3477E-3 | 2 | 20 | 1 | 6292 |
| DNA duplex unwinding | 6.3477E-3 | 2 | 20 | 1 | 6292 |
| mismatch repair | 8.5646E-3 | 2 | 27 | 1 | 6292 |
| DNA metabolic process | 8.631E-3 | 2 | 585 | 2 | 6292 |
| DNA strand elongation | 9.8303E-3 | 2 | 31 | 1 | 6292 |
| DNA strand elongation involved in DNA replication | 9.8303E-3 | 2 | 31 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
| GO Term |
P-value |
A |
B |
I |
T |
| DNA-dependent ATPase activity | 7.5032E-5 | 2 | 55 | 2 | 6292 |
| ATPase activity, coupled | 5.5711E-4 | 2 | 149 | 2 | 6292 |
| ATPase activity | 1.1194E-3 | 2 | 211 | 2 | 6292 |
| protein-DNA loading ATPase activity | 2.224E-3 | 2 | 7 | 1 | 6292 |
| DNA clamp loader activity | 2.224E-3 | 2 | 7 | 1 | 6292 |
| nucleoside-triphosphatase activity | 2.7262E-3 | 2 | 329 | 2 | 6292 |
| hydrolase activity, acting on acid anhydrides | 3.1391E-3 | 2 | 353 | 2 | 6292 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 3.1391E-3 | 2 | 353 | 2 | 6292 |
| pyrophosphatase activity | 3.1391E-3 | 2 | 353 | 2 | 6292 |
| ATP-dependent DNA helicase activity | 5.7138E-3 | 2 | 18 | 1 | 6292 |