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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Ydr128w. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 12 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
CCT6
  • chaperonin-containing T-complex
  • cytoskeleton
  • cytoplasm
  • cytoskeleton organization
  • protein folding
  • unfolded protein binding
  • CDC33
  • nucleus
  • eukaryotic translation initiation factor 4F complex
  • cytoplasm
  • ribosome
  • nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
  • translational initiation
  • translation initiation factor activity
  • CPR6
  • cytoplasm
  • protein folding
  • peptidyl-prolyl cis-trans isomerase activity
  • unfolded protein binding
  • FMP10
  • mitochondrion
  • biological_process
  • molecular_function
  • MDJ1
  • mitochondrion
  • mitochondrial inner membrane
  • proteolysis
  • protein folding
  • chaperone binding
  • unfolded protein binding
  • MTC5
  • fungal-type vacuole membrane
  • biological_process
  • molecular_function
  • NPR2
  • cellular_component
  • urea transport
  • response to drug
  • proline transport
  • molecular_function
  • POX1
  • peroxisomal matrix
  • fatty acid beta-oxidation
  • acyl-CoA oxidase activity
  • RNQ1
  • cytosol
  • biological_process
  • molecular_function
  • SEH1
  • nuclear pore
  • mRNA export from nucleus
  • rRNA export from nucleus
  • nuclear pore organization
  • snRNP protein import into nucleus
  • mRNA-binding (hnRNP) protein import into nucleus
  • snRNA export from nucleus
  • tRNA export from nucleus
  • NLS-bearing substrate import into nucleus
  • protein export from nucleus
  • ribosomal protein import into nucleus
  • structural molecule activity
  • THI21
  • cellular_component
  • thiamin biosynthetic process
  • hydroxymethylpyrimidine kinase activity
  • phosphomethylpyrimidine kinase activity
  • YHR033W
  • cytoplasm
  • biological_process
  • molecular_function
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    eukaryotic translation initiation factor 4F complex 7.6087E-3 12 4 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    protein folding 3.7206E-4 12 78 3 6292
    proline transport 3.811E-3 12 2 1 6292
    urea transport 5.7116E-3 12 3 1 6292
    neutral amino acid transport 5.7116E-3 12 3 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    unfolded protein binding 1.7927E-4 12 61 3 6292
    acyl-CoA oxidase activity 1.9072E-3 12 1 1 6292
    hydroxymethylpyrimidine kinase activity 3.811E-3 12 2 1 6292
    oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 5.7116E-3 12 3 1 6292
    phosphomethylpyrimidine kinase activity 5.7116E-3 12 3 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle