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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Tec1. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 4 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
HHF1, HHF2
  • nucleus
  • nucleoplasm part
  • nuclear nucleosome
  • chromosome
  • replication fork protection complex
  • chromatin remodeling complex
  • nucleosome
  • histone acetyltransferase complex
  • nucleoplasm
    		•
  • histone H3-K79 methylation
  • DNA repair
  • negative regulation of transcription
  • chromatin assembly or disassembly
  • positive regulation of transcription
  • nucleosome assembly
    		•
  • DNA binding
    		•
    HTB1
  • nuclear nucleosome
    		•
  • chromatin assembly or disassembly
  • postreplication repair
    		•
  • DNA binding
    		•
    STE12
  • nucleus
    		•
  • positive regulation of transcription from RNA polymerase II promoter by pheromones
  • conjugation with cellular fusion
  • pseudohyphal growth
  • invasive growth in response to glucose limitation
    		•
  • transcription factor activity
    		•
    TEC1
  • nucleus
    		•
  • pseudohyphal growth
  • invasive growth in response to glucose limitation
  • positive regulation of transcription from RNA polymerase II promoter
    		•
  • specific RNA polymerase II transcription factor activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    nuclear nucleosome 1.9966E-5 4 12 2 6292
    nucleosome 1.9966E-5 4 12 2 6292
    protein-DNA complex 4.7822E-4 4 57 2 6292
    nuclear chromatin 7.8477E-4 4 73 2 6292
    chromatin 8.7301E-4 4 77 2 6292
    replication fork protection complex 1.2712E-3 4 2 1 6292
    nuclear chromosome part 5.2287E-3 4 190 2 6292
    nuclear chromosome 7.4744E-3 4 228 2 6292
    chromosomal part 8.0617E-3 4 237 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    positive regulation of transcription 2.1685E-5 4 112 3 6292
    positive regulation of gene expression 2.1685E-5 4 112 3 6292
    positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 2.5376E-5 4 118 3 6292
    positive regulation of nitrogen compound metabolic process 2.5376E-5 4 118 3 6292
    positive regulation of macromolecule biosynthetic process 2.5376E-5 4 118 3 6292
    positive regulation of biosynthetic process 2.7369E-5 4 121 3 6292
    positive regulation of cellular biosynthetic process 2.7369E-5 4 121 3 6292
    positive regulation of macromolecule metabolic process 3.0916E-5 4 126 3 6292
    positive regulation of metabolic process 3.3184E-5 4 129 3 6292
    positive regulation of cellular metabolic process 3.3184E-5 4 129 3 6292
    positive regulation of cellular process 3.8899E-5 4 136 3 6292
    positive regulation of biological process 3.9765E-5 4 137 3 6292
    chromatin assembly or disassembly 1.7912E-4 4 35 2 6292
    invasive growth in response to glucose limitation 3.246E-4 4 47 2 6292
    histone H3-K79 methylation 6.3573E-4 4 1 1 6292
    pseudohyphal growth 6.8098E-4 4 68 2 6292
    cellular response to stimulus 8.288E-4 4 379 3 6292
    regulation of transcription 8.6159E-4 4 384 3 6292
    cell growth 1.014E-3 4 83 2 6292
    positive regulation of transcription from RNA polymerase II promoter 1.0385E-3 4 84 2 6292
    regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 1.084E-3 4 415 3 6292
    regulation of nitrogen compound metabolic process 1.0917E-3 4 416 3 6292
    filamentous growth of a population of unicellular organisms 1.1916E-3 4 90 2 6292
    growth of unicellular organism as a thread of attached cells 1.1916E-3 4 90 2 6292
    histone lysine methylation 1.2712E-3 4 2 1 6292
    regulation of gene expression 1.3321E-3 4 445 3 6292
    regulation of macromolecule biosynthetic process 1.4316E-3 4 456 3 6292
    positive regulation of transcription, DNA-dependent 1.5586E-3 4 103 2 6292
    regulation of cellular biosynthetic process 1.5848E-3 4 472 3 6292
    regulation of biosynthetic process 1.5947E-3 4 473 3 6292
    filamentous growth 1.6501E-3 4 106 2 6292
    positive regulation of RNA metabolic process 1.6812E-3 4 107 2 6292
    regulation of macromolecule metabolic process 1.7483E-3 4 488 3 6292
    regulation of cell size 1.8083E-3 4 111 2 6292
    regulation of anatomical structure size 1.9066E-3 4 114 2 6292
    regulation of cellular component size 1.9066E-3 4 114 2 6292
    regulation of primary metabolic process 2.0368E-3 4 514 3 6292
    regulation of cellular metabolic process 2.3038E-3 4 536 3 6292
    regulation of metabolic process 2.4454E-3 4 547 3 6292
    transcription 2.5116E-3 4 552 3 6292
    nucleic acid metabolic process 2.5494E-3 4 1415 4 6292
    growth 3.0699E-3 4 145 2 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 3.8261E-3 4 1566 4 6292
    positive regulation of transcription by pheromones 4.4437E-3 4 7 1 6292
    positive regulation of transcription from RNA polymerase II promoter by pheromones 4.4437E-3 4 7 1 6292
    positive regulation of gene-specific transcription from RNA polymerase II promoter 4.4437E-3 4 7 1 6292
    DNA repair 5.3374E-3 4 192 2 6292
    chromatin organization 5.954E-3 4 203 2 6292
    cellular nitrogen compound metabolic process 6.2471E-3 4 1770 4 6292
    gene-specific transcription from RNA polymerase II promoter 6.3436E-3 4 10 1 6292
    regulation of transcription by pheromones 6.3436E-3 4 10 1 6292
    regulation of transcription from RNA polymerase II promoter by pheromones 6.3436E-3 4 10 1 6292
    cellular response to pheromone 6.3436E-3 4 10 1 6292
    regulation of gene-specific transcription from RNA polymerase II promoter 6.3436E-3 4 10 1 6292
    response to stimulus 6.5381E-3 4 766 3 6292
    nitrogen compound metabolic process 6.5492E-3 4 1791 4 6292
    positive regulation of gene-specific transcription 6.9763E-3 4 11 1 6292
    regulation of cellular process 7.309E-3 4 796 3 6292
    regulation of transcription from RNA polymerase II promoter 7.4744E-3 4 228 2 6292
    response to DNA damage stimulus 7.9954E-3 4 236 2 6292
    regulation of biological process 8.0789E-3 4 824 3 6292
    regulation of gene-specific transcription 9.5041E-3 4 15 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    DNA binding 2.5835E-4 4 256 3 6292
    nucleic acid binding 4.351E-3 4 666 3 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle