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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Kin2. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 13 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
BUD14
  • incipient cellular bud site
  • cellular bud tip
  • cellular bud neck
  • cytoskeleton organization
  • cell morphogenesis during vegetative growth
  • regulation of transcription, DNA-dependent
  • protein phosphatase type 1 regulator activity
  • CMP2
  • calcineurin complex
  • cytoplasm
  • adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion
  • cellular ion homeostasis
  • calcium-dependent protein serine/threonine phosphatase activity
  • DOG1
  • cellular_component
  • glucose metabolic process
  • 2-deoxyglucose-6-phosphatase activity
  • GIS4
  • plasma membrane
  • cellular ion homeostasis
  • molecular_function
  • HSP104
  • nucleus
  • cytoplasm
  • telomere maintenance
  • chaperone mediated protein folding requiring cofactor
  • protein refolding
  • response to stress
  • chaperone binding
  • ATPase activity, coupled
  • KEL1
  • cellular bud tip
  • cytoplasm
  • cellular bud neck
  • mating projection tip
  • regulation of cell shape
  • negative regulation of exit from mitosis
  • cell morphogenesis
  • cytogamy
  • plasma membrane fusion
  • molecular_function
  • KEL2
  • cellular bud tip
  • cellular bud neck
  • mating projection tip
  • negative regulation of exit from mitosis
  • conjugation with cellular fusion
  • molecular_function
  • KIN2
  • membrane fraction
  • plasma membrane
  • exocytosis
  • protein kinase activity
  • KRE6
  • integral to membrane
  • Golgi cis cisterna
  • cellular cell wall organization
  • 1,6-beta-glucan biosynthetic process
  • glucosidase activity
  • POP2
  • cytoplasm
  • CCR4-NOT core complex
  • nuclear-transcribed mRNA poly(A) tail shortening
  • regulation of transcription from RNA polymerase II promoter
  • RNA elongation from RNA polymerase II promoter
  • 3'-5'-exoribonuclease activity
  • TEF4
  • mitochondrion
  • ribosome
  • eukaryotic translation elongation factor 1 complex
  • translational elongation
  • translation elongation factor activity
  • TFC4
  • transcription factor TFIIIC complex
  • transcription initiation from RNA polymerase III promoter
  • RNA polymerase III transcription factor activity
  • UBA1
  • nucleus
  • cytoplasm
  • ubiquitin cycle
  • ubiquitin activating enzyme activity
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cellular bud tip 1.8907E-4 13 57 3 6292
    cellular bud neck 2.0717E-3 13 129 3 6292
    mating projection tip 2.2564E-3 13 35 2 6292
    cell projection part 3.2387E-3 13 42 2 6292
    cellular bud 4.2448E-3 13 166 3 6292
    cell projection 4.3876E-3 13 49 2 6292
    mating projection 4.3876E-3 13 49 2 6292
    site of polarized growth 4.3905E-3 13 168 3 6292
    calcineurin complex 8.2408E-3 13 4 1 6292
    transcription factor complex 9.0369E-3 13 71 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    negative regulation of exit from mitosis 2.3591E-5 13 4 2 6292
    regulation of exit from mitosis 1.151E-3 13 25 2 6292
    exit from mitosis 1.151E-3 13 25 2 6292
    negative regulation of cell cycle process 1.8876E-3 13 32 2 6292
    conjugation with cellular fusion 1.8925E-3 13 125 3 6292
    conjugation 1.9364E-3 13 126 3 6292
    chaperone-mediated protein folding 2.0661E-3 13 1 1 6292
    'de novo' posttranslational protein folding 2.0661E-3 13 1 1 6292
    chaperone mediated protein folding requiring cofactor 2.0661E-3 13 1 1 6292
    multi-organism process 2.7814E-3 13 143 3 6292
    regulation of cell shape 4.1283E-3 13 2 1 6292
    biological regulation 5.6132E-3 13 1213 7 6292
    plasma membrane fusion 6.1865E-3 13 3 1 6292
    1,6-beta-glucan biosynthetic process 8.2408E-3 13 4 1 6292
    ubiquitin cycle 8.2408E-3 13 4 1 6292
    regulation of mitotic cell cycle 9.0369E-3 13 71 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    ubiquitin activating enzyme activity 2.0661E-3 13 1 1 6292
    2-deoxyglucose-6-phosphatase activity 4.1283E-3 13 2 1 6292
    calcium-dependent protein serine/threonine phosphatase activity 6.1865E-3 13 3 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle