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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Rrp9. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 6 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

small nucleolar ribonucleoprotein complex 2.8041E-5 6 72 3 6292
nuclear outer membrane 4.7876E-5 6 86 3 6292
nuclear membrane 6.87E-5 6 97 3 6292
outer membrane 4.1815E-4 6 178 3 6292
organelle outer membrane 4.1815E-4 6 178 3 6292
nuclear envelope 5.8088E-4 6 199 3 6292
nuclear membrane-endoplasmic reticulum network 9.1135E-4 6 232 3 6292
box C/D snoRNP complex 1.9064E-3 6 2 1 6292
endomembrane system 4.3509E-3 6 398 3 6292
envelope 8.5521E-3 6 505 3 6292
organelle envelope 8.5521E-3 6 505 3 6292
TORC2 complex 8.5551E-3 6 9 1 6292
ribonucleoprotein complex 8.9879E-3 6 514 3 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

maturation of SSU-rRNA 1.5357E-5 6 59 3 6292
rRNA modification 1.1517E-4 6 18 2 6292
ribosome biogenesis 1.2345E-4 6 346 4 6292
rRNA processing 1.5729E-4 6 128 3 6292
ribonucleoprotein complex biogenesis 1.675E-4 6 374 4 6292
rRNA metabolic process 1.9253E-4 6 137 3 6292
ncRNA processing 7.2911E-4 6 215 3 6292
ncRNA metabolic process 1.2291E-3 6 257 3 6292
RNA modification 1.7782E-3 6 70 2 6292
cellular component biogenesis 1.8339E-3 6 694 4 6292
ncRNA 5'-end processing 2.8585E-3 6 3 1 6292
proline biosynthetic process 2.8585E-3 6 3 1 6292
endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 2.8585E-3 6 3 1 6292
rRNA 5'-end processing 2.8585E-3 6 3 1 6292
RNA 5'-end processing 2.8585E-3 6 3 1 6292
endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 2.8585E-3 6 3 1 6292
maturation of 5.8S rRNA 3.8098E-3 6 4 1 6292
cleavage involved in rRNA processing 3.8098E-3 6 4 1 6292
maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 3.8098E-3 6 4 1 6292
endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 3.8098E-3 6 4 1 6292
endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 3.8098E-3 6 4 1 6292
endonucleolytic cleavage involved in rRNA processing 3.8098E-3 6 4 1 6292
RNA processing 3.811E-3 6 380 3 6292
regulation of Ras protein signal transduction 5.7102E-3 6 6 1 6292
negative regulation of Ras protein signal transduction 5.7102E-3 6 6 1 6292
negative regulation of cell communication 5.7102E-3 6 6 1 6292
negative regulation of small GTPase mediated signal transduction 5.7102E-3 6 6 1 6292
regulation of small GTPase mediated signal transduction 5.7102E-3 6 6 1 6292
negative regulation of signaling pathway 5.7102E-3 6 6 1 6292
proline metabolic process 6.6592E-3 6 7 1 6292
establishment or maintenance of actin cytoskeleton polarity 8.5551E-3 6 9 1 6292
establishment or maintenance of cytoskeleton polarity 8.5551E-3 6 9 1 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

snoRNA binding 3.4811E-4 6 31 2 6292
glutamate 5-kinase activity 9.5359E-4 6 1 1 6292
amino acid kinase activity 2.8585E-3 6 3 1 6292
phosphotransferase activity, carboxyl group as acceptor 4.7604E-3 6 5 1 6292
GTPase binding 9.5019E-3 6 10 1 6292
small GTPase binding 9.5019E-3 6 10 1 6292
Ras GTPase binding 9.5019E-3 6 10 1 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle