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Any process that decreases the rate, frequency or extent of the growth hormone receptor signaling pathway. The growth hormone receptor signaling pathway is the series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand. Any process that stops, prevents or reduces the frequency, rate or extent of signaling via the stress-activated protein kinase signaling pathway. Any process that stops, prevents or reduces the frequency, rate or extent of the Tl signaling pathway. Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor signaling pathway. Process by which metarhodopsin is prevented from generating molecular signals. Any process that stops, prevents or reduces the frequency, rate or extent of the activity of the nerve growth factor receptor. Any process that decreases the rate, frequency or extent of the red or far-red signaling pathway, the series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light. Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. Any process that stops, prevents or reduces the frequency, rate or extent of signaling in response to detection of lipopolysaccharide. Any process that decreases the rate, frequency or extent of a series of reactions, mediated by protein kinases, which occurs as a result of a single trigger reaction or compound. Any process that stops, prevents or reduces the frequency, rate or extent of a signaling pathway. Any process that stops, prevents or reduces the frequency, rate or extent of the Notch signaling pathway. Any process that modulates the frequency, rate or extent of a signaling pathway. Any process that stops, prevents or reduces the frequency, rate or extent of the activity of the IP3 receptor. Any process that stops, prevents or reduces the frequency, rate or extent of G-protein coupled receptor protein signaling pathway activity. The entirety of a process whereby information is transmitted. This process begins with the initiation of the signal and ends when a response has been triggered. Any process that stops, prevents or reduces the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity. Any process that stops, prevents or reduces the frequency, rate or extent of signal transduction mediated by the phosphoinositide 3-kinase cascade. Any process that stops or prevents ethylene (ethene) mediated signaling. The negative regulation of a signal transduction pathway in response to a stimulus upon prolonged exposure to that stimulus. Any process that decreases the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway. Any process that stops, prevents or reduces the frequency, rate or extent of the activity of the nerve growth factor receptor signaling pathway. Any process that stops, prevents or reduces the frequency, rate or extent of the Roundabout signaling pathway. Any process that decreases the rate, frequency or extent of nitric oxide mediated signal transduction. Nitric oxide mediated signal transduction is a series of molecular signals mediated by the detection of nitric oxide (NO). Any process that stops, prevents or reduces the frequency, rate or extent of hippo signaling. Any process that stops, prevents or reduces the frequency, rate or extent of gibberellic acid mediated signaling activity. Any process that stops, prevents or reduces the frequency, rate or extent of retinoic acid receptor signaling pathway activity. Any process that decreases the rate, frequency or extent of cGMP-mediated signaling. cGMP-mediated signaling is a series of molecular signals in which a cell uses cyclic GMP to convert an extracellular signal into a response. Any process that decreases the rate, frequency or extent of auxin mediated signaling pathway. Auxin mediated signaling pathway is the series of molecular signals generated in response to detection of auxin. Any process that stops, prevents or reduces the frequency, rate or extent of calcium-mediated signaling. Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity. Any process that stops, prevents or reduces the frequency, rate or extent of signaling via the TOR signaling pathway. Any process that stops, prevents or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell. Any process that stops, prevents or reduces the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway. Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of any steroid hormone receptor signaling pathway. Any process that stops, prevents or reduces the frequency, rate or extent of Wnt receptor signaling pathway activity. Any process that stops, prevents or reduces the frequency, rate or extent of smoothened signaling. Any process that stops, prevents or reduces the frequency, rate or extent of signaling via the brain-derived neurotrophic factor receptor signaling pathway. Any process that stops, prevents or reduces the frequency, rate or extent of the sevenless signaling pathway. Any process that stops, prevents or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. Any process that stops, prevents, or reduces the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing (NOD) pathway. Any process that decreases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. Any process that stops, prevents or reduces the frequency, rate or extent of the cytokine mediated signaling pathway. Any process that decreases the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand. Any process that stops, prevents or reduces the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway. Any process which stops, prevents or reduces the frequency, rate or extent of cAMP-mediated signaling, a series of molecular signals in which a cell uses cyclic AMP to convert an extracellular signal into a response. Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. Any process that stops, prevents or reduces the frequency, rate or extent of signal transduction mediated by abscisic acid. Any process that stops, prevents or reduces the frequency, rate or extent of thyroid hormone mediated signaling pathway. The series of molecular events whereby information is sent from one location to another within a living organism or between living organisms. Any process that stops, prevents or reduces the frequency, rate or extent of insulin receptor signaling. Any process that stops, prevents or reduces the frequency, rate or extent of small GTPase mediated signal transduction. Any process that stops, prevents or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. Any process that stops, prevents or reduces the frequency, rate or extent of the vitamin D receptor signaling pathway activity. Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end. Any process that stops, prevents or reduces the frequency, rate or extent of signal transduction mediated by cytokinin. Any process that stops, prevents or reduces the frequency, rate or extent of insulin-like growth factor receptor signaling. Any process by which an organism stops, prevents or reduces the frequency, rate or extent of the salicylic acid-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity. Any process that stops, prevents or reduces the frequency, rate or extent of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: negative regulation of signaling pathway
Acc: GO:0035467
Aspect: Biological Process
Desc: Any process that stops, prevents or reduces the frequency, rate or extent of a signaling pathway.
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 771 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0035467 - negative regulation of signaling pathway (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle