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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Trf4. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 11 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
AIR1
  • nucleus
  • nucleolus
  • TRAMP complex
  • mRNA export from nucleus
  • rRNA catabolic process
  • snRNA catabolic process
  • snoRNA catabolic process
  • tRNA catabolic process
  • ncRNA polyadenylation involved in polyadenylation-dependent ncRNA catabolic process
  • polynucleotide adenylyltransferase activity
  • AIR2
  • nucleus
  • TRAMP complex
  • mRNA export from nucleus
  • rRNA catabolic process
  • snRNA catabolic process
  • snoRNA catabolic process
  • tRNA catabolic process
  • ncRNA polyadenylation involved in polyadenylation-dependent ncRNA catabolic process
  • polynucleotide adenylyltransferase activity
  • IMD1
    IMD3
  • cytoplasm
  • GTP biosynthetic process
  • IMP dehydrogenase activity
  • IMD4
  • cytoplasm
  • biological_process
  • IMP dehydrogenase activity
  • MTR4
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • TRAMP complex
  • mRNA export from nucleus
  • rRNA catabolic process
  • ribosome biogenesis
  • tRNA catabolic process
  • ncRNA polyadenylation involved in polyadenylation-dependent ncRNA catabolic process
  • polyadenylation-dependent ncRNA catabolic process
  • ATP-dependent RNA helicase activity
  • NAP1
  • nucleus
  • cytoplasm
  • nuclear nucleosome
  • M phase of mitotic cell cycle
  • budding cell bud growth
  • nucleosome assembly
  • histone binding
  • NOP53
  • nucleus
  • nucleolus
  • ribosomal large subunit export from nucleus
  • ribosome biogenesis
  • processing of 27S pre-rRNA
  • rRNA binding
  • NOP56
  • box C/D snoRNP complex
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • rRNA modification
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • molecular_function
  • PAP2
  • nucleus
  • TRAMP complex
  • mitotic chromosome condensation
  • ncRNA polyadenylation
  • mitotic sister chromatid cohesion
  • rRNA catabolic process
  • snRNA catabolic process
  • snoRNA catabolic process
  • tRNA catabolic process
  • DNA topological change
  • ncRNA polyadenylation involved in polyadenylation-dependent ncRNA catabolic process
  • polyadenylation-dependent ncRNA catabolic process
  • DNA-directed DNA polymerase activity
  • polynucleotide adenylyltransferase activity
  • PSE1
  • nucleus
  • cytoplasm
  • mRNA export from nucleus
  • protein import into nucleus
  • protein transmembrane transporter activity
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    TRAMP complex 5.0581E-12 11 4 4 6292
    nucleolus 3.3697E-4 11 211 4 6292
    nuclear part 8.5482E-4 11 1103 7 6292
    box C/D snoRNP complex 3.4937E-3 11 2 1 6292
    nuclear lumen 5.8201E-3 11 453 4 6292
    nucleus 7.2902E-3 11 2041 8 6292
    nuclear outer membrane 9.3747E-3 11 86 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    tRNA catabolic process 5.0581E-12 11 4 4 6292
    ncRNA polyadenylation 7.5736E-11 11 6 4 6292
    ncRNA polyadenylation involved in polyadenylation-dependent ncRNA catabolic process 7.5736E-11 11 6 4 6292
    rRNA catabolic process 7.5736E-11 11 6 4 6292
    ncRNA catabolic process 7.5736E-11 11 6 4 6292
    polyadenylation-dependent RNA catabolic process 3.528E-10 11 8 4 6292
    polyadenylation-dependent ncRNA catabolic process 3.528E-10 11 8 4 6292
    ncRNA 3'-end processing 2.486E-9 11 12 4 6292
    snRNA catabolic process 3.9687E-8 11 5 3 6292
    snoRNA catabolic process 3.9687E-8 11 5 3 6292
    RNA polyadenylation 7.4149E-8 11 26 4 6292
    snRNA metabolic process 3.321E-7 11 9 3 6292
    nuclear export 4.5576E-7 11 103 5 6292
    RNA 3'-end processing 5.4727E-7 11 42 4 6292
    nuclear transport 1.4582E-6 11 130 5 6292
    nucleocytoplasmic transport 1.4582E-6 11 130 5 6292
    rRNA metabolic process 1.8923E-6 11 137 5 6292
    snoRNA metabolic process 3.1985E-6 11 18 3 6292
    mRNA transport 3.8902E-6 11 68 4 6292
    mRNA export from nucleus 3.8902E-6 11 68 4 6292
    RNA catabolic process 7.4742E-6 11 80 4 6292
    RNA export from nucleus 7.4742E-6 11 80 4 6292
    RNA transport 7.8554E-6 11 81 4 6292
    nucleic acid transport 7.8554E-6 11 81 4 6292
    establishment of RNA localization 7.8554E-6 11 81 4 6292
    RNA localization 1.3063E-5 11 92 4 6292
    nucleobase, nucleoside, nucleotide and nucleic acid transport 1.5475E-5 11 96 4 6292
    ncRNA processing 1.737E-5 11 215 5 6292
    tRNA metabolic process 3.7449E-5 11 120 4 6292
    ncRNA metabolic process 4.1279E-5 11 257 5 6292
    modification-dependent macromolecule catabolic process 1.2728E-4 11 164 4 6292
    RNA processing 2.6696E-4 11 380 5 6292
    cellular macromolecule catabolic process 8.0284E-4 11 265 4 6292
    macromolecule catabolic process 1.1871E-3 11 294 4 6292
    DNA packaging 1.3395E-3 11 32 2 6292
    intracellular transport 1.5196E-3 11 553 5 6292
    establishment of localization in cell 2.1821E-3 11 599 5 6292
    cellular localization 2.999E-3 11 643 5 6292
    GTP biosynthetic process 3.4937E-3 11 2 1 6292
    macromolecule localization 3.6093E-3 11 397 4 6292
    cellular catabolic process 4.2414E-3 11 415 4 6292
    DNA conformation change 4.3546E-3 11 58 2 6292
    catabolic process 8.046E-3 11 496 4 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    polynucleotide adenylyltransferase activity 7.9298E-8 11 6 3 6292
    adenylyltransferase activity 1.1264E-6 11 13 3 6292
    IMP dehydrogenase activity 8.329E-6 11 3 2 6292
    nucleotidyltransferase activity 2.6346E-3 11 168 3 6292
    oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 6.8247E-3 11 73 2 6292
    oxidoreductase activity, acting on CH-OH group of donors 8.35E-3 11 81 2 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle