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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Pre1. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 15 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
ADD66
  • cytoplasm
  • ER-associated protein catabolic process
  • molecular_function
  • PBA1
  • cytoplasm
  • biological_process
  • molecular_function
  • PRE1
  • nucleus
  • proteasome core complex, beta-subunit complex
  • ascospore formation
  • response to stress
  • ubiquitin-dependent protein catabolic process
  • endopeptidase activity
  • PRE10
  • proteasome core complex, alpha-subunit complex
  • ubiquitin-dependent protein catabolic process
  • endopeptidase activity
  • PRE2
  • proteasome core complex, beta-subunit complex
  • ubiquitin-dependent protein catabolic process
  • endopeptidase activity
  • PRE3
  • proteasome core complex, beta-subunit complex
  • ascospore formation
  • response to stress
  • ubiquitin-dependent protein catabolic process
  • endopeptidase activity
  • PRE5
  • proteasome core complex, alpha-subunit complex
  • ubiquitin-dependent protein catabolic process
  • endopeptidase activity
  • PRE6
  • mitochondrion
  • proteasome core complex, alpha-subunit complex
  • cytosol
  • ubiquitin-dependent protein catabolic process
  • endopeptidase activity
  • PRE7
  • proteasome core complex, beta-subunit complex
  • ubiquitin-dependent protein catabolic process
  • endopeptidase activity
  • PRE8
  • proteasome core complex, alpha-subunit complex
  • ubiquitin-dependent protein catabolic process
  • endopeptidase activity
  • PRE9
  • proteasome core complex, alpha-subunit complex
  • filamentous growth
  • ubiquitin-dependent protein catabolic process
  • endopeptidase activity
  • PUP2
  • proteasome core complex, alpha-subunit complex
  • ascospore formation
  • response to stress
  • ubiquitin-dependent protein catabolic process
  • endopeptidase activity
  • PUP3
  • proteasome core complex, beta-subunit complex
  • ubiquitin-dependent protein catabolic process
  • endopeptidase activity
  • SCL1
  • mitochondrion
  • proteasome core complex, alpha-subunit complex
  • ubiquitin-dependent protein catabolic process
  • endopeptidase activity
  • YHR033W
  • cytoplasm
  • biological_process
  • molecular_function
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    proteasome core complex 1.0393E-31 15 16 12 6292
    proteasome complex 3.9225E-24 15 48 12 6292
    proteasome core complex, alpha-subunit complex 8.335E-20 15 7 7 6292
    proteasome core complex, beta-subunit complex 7.6657E-13 15 7 5 6292
    protein complex 3.0599E-7 15 1137 12 6292
    macromolecular complex 1.8508E-5 15 1635 12 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    modification-dependent protein catabolic process 8.1505E-20 15 156 13 6292
    ubiquitin-dependent protein catabolic process 8.1505E-20 15 156 13 6292
    proteolysis involved in cellular protein catabolic process 1.0536E-19 15 159 13 6292
    modification-dependent macromolecule catabolic process 1.5983E-19 15 164 13 6292
    cellular protein catabolic process 2.803E-19 15 171 13 6292
    proteolysis 9.9835E-19 15 188 13 6292
    protein catabolic process 1.0718E-18 15 189 13 6292
    cellular macromolecule catabolic process 9.5861E-17 15 265 13 6292
    macromolecule catabolic process 3.7765E-16 15 294 13 6292
    cellular catabolic process 3.4774E-14 15 415 13 6292
    catabolic process 3.551E-13 15 496 13 6292
    cellular protein metabolic process 7.3372E-9 15 1074 13 6292
    protein metabolic process 1.495E-8 15 1136 13 6292
    cellular macromolecule metabolic process 8.6671E-5 15 2285 13 6292
    macromolecule metabolic process 1.2073E-4 15 2349 13 6292
    primary metabolic process 1.4206E-3 15 2896 13 6292
    sexual sporulation 2.1374E-3 15 112 3 6292
    sexual sporulation resulting in formation of a cellular spore 2.1374E-3 15 112 3 6292
    cell development 2.1374E-3 15 112 3 6292
    ascospore formation 2.1374E-3 15 112 3 6292
    cellular metabolic process 2.4151E-3 15 3033 13 6292
    sporulation 2.9247E-3 15 125 3 6292
    sporulation resulting in formation of a cellular spore 2.9247E-3 15 125 3 6292
    anatomical structure formation involved in morphogenesis 3.1985E-3 15 129 3 6292
    reproductive process in single-celled organism 3.5625E-3 15 134 3 6292
    metabolic process 3.8068E-3 15 3157 13 6292
    cell differentiation 4.7143E-3 15 148 3 6292
    reproductive developmental process 4.9873E-3 15 151 3 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    endopeptidase activity 1.9261E-23 15 54 12 6292
    peptidase activity, acting on L-amino acid peptides 3.0137E-20 15 95 12 6292
    peptidase activity 1.9473E-16 15 192 12 6292
    hydrolase activity 2.3726E-8 15 911 12 6292
    catalytic activity 3.6565E-4 15 2150 12 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle