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Protein Overview: PBA1

General Information:
Name(s) found: PBA1 / YLR199C [SGD]
Description(s) found:
Found 21 descriptions.
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  • Protein involved in 20S proteasome assembly; forms a heterodimer with Add66p that binds to proteasome precursors; similar to human PAC1 constituent of the PAC1-PAC2 complex involved in proteasome assembly [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 276 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLFKQWNDLP EPKHLLDLPE ISKNLQSLEV CPVPKVEFPQ DLDVPQYSTA VITTKIMNPL  60
   61 FPKNLLQLTS IGEIKTTLTV KSPSLPQSSG KHSWNYDENF PNEVDPDQKN DTADETVYGF 120
  121 SFPIYSFGKT LLFSMEENFI SISPIFGNMI SRSIISQLAQ FSPDIIVIGT SDKIASMKVM 180
  181 TENECTLQPP EFITGFIGSV LTQLIVGPSK GLKFKCLVAP SEGPNGFEKL SLSDMGSLVD 240
  241 LCGQWLGFEP SRYSEECYRL WRCDSAAIGA QSGLYI

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) ADD66 PBA1 PRE5 PRE9 PUP2 SCL1
    View Details Krogan NJ, et al. (2006) ADD66 PBA1 PDC6
    View Details Ho Y, et al. (2002) ADD66 PBA1 PRE1 PRE10 PRE2 PRE3 PRE5 PRE6 PRE7 PRE8 PRE9 PUP2 PUP3 SCL1 YHR033W

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data PBA1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..85] deduced N/A No confident structure predictions are available.
    2 View Details [86..276] MSA 1.006971 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle