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View Protein Complex Details

Complex Overview

From Publication: Gavin A.C. et al. (2006) Proteome survey reveals modularity of the yeast cell machinery. Nature. 2006 Mar 30;440(7084):631-6. Epub 2006 Jan 22.
Notes: From the published set of protein complexes (core proteins only)
Complex Size: 7 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

HOPS complex 8.1421E-20 7 6 6 6292
vacuolar membrane 2.0271E-10 7 113 6 6292
vacuolar part 3.0802E-10 7 121 6 6292
fungal-type vacuole 1.5651E-9 7 158 6 6292
lytic vacuole 1.5651E-9 7 158 6 6292
storage vacuole 1.5651E-9 7 158 6 6292
vacuole 8.524E-9 7 209 6 6292
fungal-type vacuole membrane 6.0093E-7 7 74 4 6292
membrane part 8.472E-6 7 662 6 6292
organelle membrane 1.1014E-5 7 692 6 6292
protein complex 2.0393E-4 7 1137 6 6292
membrane 2.7648E-4 7 1198 6 6292
macromolecular complex 1.6651E-3 7 1635 6 6292
extrinsic to vacuolar membrane 2.224E-3 7 2 1 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

vacuole fusion, non-autophagic 2.4032E-14 7 27 6 6292
vacuole organization 7.5849E-13 7 46 6 6292
membrane fusion 8.0578E-12 7 67 6 6292
cellular membrane fusion 8.0578E-12 7 67 6 6292
late endosome to vacuole transport 1.0824E-11 7 24 5 6292
Golgi to endosome transport 1.7656E-10 7 11 4 6292
endosome transport 6.5693E-10 7 52 5 6292
cellular membrane organization 6.147E-9 7 198 6 6292
membrane organization 6.147E-9 7 198 6 6292
vacuolar transport 3.8145E-8 7 115 5 6292
post-Golgi vesicle-mediated transport 4.263E-7 7 68 4 6292
vesicle-mediated transport 8.5922E-6 7 340 5 6292
Golgi vesicle transport 1.6125E-5 7 168 4 6292
vesicle docking during exocytosis 6.966E-5 7 12 2 6292
intracellular transport 9.3173E-5 7 553 5 6292
transport 9.4619E-5 7 997 6 6292
membrane docking 9.5944E-5 7 14 2 6292
vesicle docking 9.5944E-5 7 14 2 6292
establishment of localization 1.009E-4 7 1008 6 6292
localization 1.3542E-4 7 1060 6 6292
establishment of localization in cell 1.3731E-4 7 599 5 6292
cellular localization 1.9347E-4 7 643 5 6292
organelle organization 1.9369E-4 7 1127 6 6292
exocytosis 1.0729E-3 7 46 2 6292
cellular component organization 1.3786E-3 7 1582 6 6292
secretion 1.477E-3 7 54 2 6292
secretion by cell 1.477E-3 7 54 2 6292
vacuolar protein processing 5.552E-3 7 5 1 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

Rab guanyl-nucleotide exchange factor activity 1.5882E-5 7 6 2 6292
Ras guanyl-nucleotide exchange factor activity 1.6097E-4 7 18 2 6292
guanyl-nucleotide exchange factor activity 7.3181E-4 7 38 2 6292
small GTPase regulator activity 1.7614E-3 7 59 2 6292
GTPase regulator activity 3.5412E-3 7 84 2 6292
nucleoside-triphosphatase regulator activity 4.5092E-3 7 95 2 6292

YRC Informatics Platform - Version 3.0
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