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View Protein Complex Details

Complex Overview

From Publication: Krogan N. J. et al. (2006) Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature. 2006 Mar 30;440(7084):637-43. Epub 2006 Mar 22.
Notes: From the published set of core protein complex predictions.
Complex Size: 3 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

histone deacetylase complex 4.2679E-8 3 23 3 6292
chromatin remodeling complex 3.7798E-6 3 99 3 6292
nucleoplasm part 5.8345E-5 3 245 3 6292
nucleoplasm 7.3064E-5 3 264 3 6292
nuclear lumen 3.709E-4 3 453 3 6292
organelle lumen 1.1495E-3 3 660 3 6292
intracellular organelle lumen 1.1495E-3 3 660 3 6292
membrane-enclosed lumen 1.3717E-3 3 700 3 6292
nuclear part 5.3751E-3 3 1103 3 6292
protein complex 5.8881E-3 3 1137 3 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

protein amino acid deacetylation 8.8056E-8 3 29 3 6292
chromatin modification 1.8706E-5 3 168 3 6292
chromatin organization 3.3104E-5 3 203 3 6292
histone deacetylation 5.3064E-5 3 27 2 6292
post-translational protein modification 1.8121E-4 3 357 3 6292
regulation of transcription, DNA-dependent 1.8274E-4 3 358 3 6292
regulation of RNA metabolic process 1.9053E-4 3 363 3 6292
regulation of transcription 2.2565E-4 3 384 3 6292
regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 2.85E-4 3 415 3 6292
regulation of nitrogen compound metabolic process 2.8707E-4 3 416 3 6292
regulation of gene expression 3.5155E-4 3 445 3 6292
regulation of macromolecule biosynthetic process 3.7833E-4 3 456 3 6292
regulation of cellular biosynthetic process 4.1966E-4 3 472 3 6292
regulation of biosynthetic process 4.2234E-4 3 473 3 6292
regulation of macromolecule metabolic process 4.639E-4 3 488 3 6292
protein modification process 4.9605E-4 3 499 3 6292
transcription, DNA-dependent 5.081E-4 3 503 3 6292
RNA biosynthetic process 5.2344E-4 3 508 3 6292
regulation of primary metabolic process 5.4224E-4 3 514 3 6292
covalent chromatin modification 5.7496E-4 3 88 2 6292
histone modification 5.7496E-4 3 88 2 6292
regulation of cellular metabolic process 6.1504E-4 3 536 3 6292
regulation of metabolic process 6.5376E-4 3 547 3 6292
transcription 6.7188E-4 3 552 3 6292
chromosome organization 6.8292E-4 3 555 3 6292
macromolecule modification 7.3601E-4 3 569 3 6292
regulation of cellular process 2.0181E-3 3 796 3 6292
regulation of biological process 2.2389E-3 3 824 3 6292
RNA metabolic process 3.4763E-3 3 954 3 6292
loss of chromatin silencing involved in replicative cell aging 4.2857E-3 3 9 1 6292
progressive alteration of chromatin involved in replicative cell aging 4.7611E-3 3 10 1 6292
loss of chromatin silencing 4.7611E-3 3 10 1 6292
cellular protein metabolic process 4.9618E-3 3 1074 3 6292
progressive alteration of chromatin involved in cell aging 5.2364E-3 3 11 1 6292
positive regulation of gene expression, epigenetic 5.2364E-3 3 11 1 6292
regulation of gene silencing 5.2364E-3 3 11 1 6292
negative regulation of gene silencing 5.2364E-3 3 11 1 6292
regulation of chromatin silencing 5.2364E-3 3 11 1 6292
negative regulation of chromatin silencing 5.2364E-3 3 11 1 6292
organelle organization 5.734E-3 3 1127 3 6292
protein metabolic process 5.8726E-3 3 1136 3 6292
cellular macromolecule biosynthetic process 6.7003E-3 3 1187 3 6292
macromolecule biosynthetic process 6.7343E-3 3 1189 3 6292
biological regulation 7.1507E-3 3 1213 3 6292
gene expression 8.4626E-3 3 1283 3 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

histone deacetylase activity 1.1953E-7 3 32 3 6292
protein deacetylase activity 1.1953E-7 3 32 3 6292
deacetylase activity 1.5773E-7 3 35 3 6292
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 4.1681E-7 3 48 3 6292
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1.9799E-6 3 80 3 6292
hydrolase activity 3.0267E-3 3 911 3 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle