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View Protein Complex Details

Complex Overview

From Publication: Krogan N. J. et al. (2006) Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature. 2006 Mar 30;440(7084):637-43. Epub 2006 Mar 22.
Notes: From the published set of core protein complex predictions.
Complex Size: 7 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
GAL83
  • nucleus
  • cytoplasm
  • nuclear envelope lumen
  • AMP-activated protein kinase complex
  • signal transduction
  • regulation of protein complex assembly
  • cell adhesion
  • invasive growth in response to glucose limitation
  • protein amino acid phosphorylation
  • AMP-activated protein kinase activity
  • RAD30
  • replication fork
  • mutagenesis
  • DNA repair
  • DNA replication
  • translesion synthesis
  • DNA binding
  • DNA-directed DNA polymerase activity
  • nucleotidyltransferase activity
  • metal ion binding
  • transferase activity
  • damaged DNA binding
  • SAK1
  • cytoplasm
  • DNA-dependent DNA replication
  • glucose metabolic process
  • protein amino acid phosphorylation
  • protein kinase activity
  • SIP1
  • vacuole
  • AMP-activated protein kinase complex
  • signal transduction
  • regulation of protein complex assembly
  • protein amino acid phosphorylation
  • AMP-activated protein kinase activity
  • SIP2
  • cytoplasm
  • plasma membrane
  • AMP-activated protein kinase complex
  • signal transduction
  • regulation of protein complex assembly
  • invasive growth in response to glucose limitation
  • protein amino acid phosphorylation
  • replicative cell aging
  • cellular response to glucose starvation
  • AMP-activated protein kinase activity
  • SNF1
  • nucleus
  • cytoplasm
  • mitochondrion
  • fungal-type vacuole
  • nuclear envelope lumen
  • AMP-activated protein kinase complex
  • regulation of carbohydrate metabolic process
  • signal transduction
  • pseudohyphal growth
  • cell adhesion
  • invasive growth in response to glucose limitation
  • protein amino acid phosphorylation
  • replicative cell aging
  • biofilm formation
  • positive regulation of gluconeogenesis
  • cellular response to nitrogen starvation
  • AMP-activated protein kinase activity
  • SNF4
  • nucleus
  • cytoplasm
  • nuclear envelope lumen
  • plasma membrane
  • AMP-activated protein kinase complex
  • peroxisome organization
  • protein amino acid phosphorylation
  • replicative cell aging
  • positive regulation of gluconeogenesis
  • regulation of transcription from RNA polymerase II promoter
  • AMP-activated protein kinase activity
  • protein serine/threonine kinase activator activity
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    AMP-activated protein kinase complex 1.5353E-15 7 6 5 6292
    nuclear envelope lumen 3.3722E-9 7 4 3 6292
    organelle envelope lumen 8.1872E-6 7 40 3 6292
    nuclear envelope 9.9288E-4 7 199 3 6292
    protein complex 2.9048E-3 7 1137 5 6292
    endomembrane system 7.2588E-3 7 398 3 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    protein amino acid phosphorylation 1.1488E-10 7 103 6 6292
    phosphorylation 3.3372E-9 7 179 6 6292
    phosphorus metabolic process 1.4802E-8 7 229 6 6292
    phosphate metabolic process 1.4802E-8 7 229 6 6292
    regulation of protein complex assembly 1.3864E-7 7 11 3 6292
    post-translational protein modification 2.1368E-7 7 357 6 6292
    regulation of cellular component biogenesis 6.8335E-7 7 18 3 6292
    protein modification process 1.5801E-6 7 499 6 6292
    macromolecule modification 3.4506E-6 7 569 6 6292
    positive regulation of gluconeogenesis 6.3596E-6 7 4 2 6292
    replicative cell aging 6.9973E-6 7 38 3 6292
    invasive growth in response to glucose limitation 1.3392E-5 7 47 3 6292
    cell aging 1.5202E-5 7 49 3 6292
    aging 1.7166E-5 7 51 3 6292
    biological adhesion 2.9615E-5 7 8 2 6292
    positive regulation of glucose metabolic process 2.9615E-5 7 8 2 6292
    cell adhesion 2.9615E-5 7 8 2 6292
    positive regulation of cellular carbohydrate metabolic process 2.9615E-5 7 8 2 6292
    positive regulation of carbohydrate metabolic process 2.9615E-5 7 8 2 6292
    signal transduction 4.2023E-5 7 214 4 6292
    signal transmission 4.4395E-5 7 217 4 6292
    signaling process 4.4395E-5 7 217 4 6292
    regulation of cellular component organization 5.5024E-5 7 75 3 6292
    signaling 7.9951E-5 7 252 4 6292
    filamentous growth of a population of unicellular organisms 9.5043E-5 7 90 3 6292
    growth of unicellular organism as a thread of attached cells 9.5043E-5 7 90 3 6292
    regulation of gluconeogenesis 1.2639E-4 7 16 2 6292
    cellular protein metabolic process 1.4622E-4 7 1074 6 6292
    filamentous growth 1.5488E-4 7 106 3 6292
    regulation of cellular ketone metabolic process 1.6097E-4 7 18 2 6292
    glucose metabolic process 1.6829E-4 7 109 3 6292
    protein metabolic process 2.0289E-4 7 1136 6 6292
    regulation of carbohydrate biosynthetic process 2.4252E-4 7 22 2 6292
    cellular response to starvation 2.4252E-4 7 22 2 6292
    response to starvation 2.4252E-4 7 22 2 6292
    hexose metabolic process 2.4682E-4 7 124 3 6292
    monosaccharide metabolic process 3.1745E-4 7 135 3 6292
    growth 3.9206E-4 7 145 3 6292
    regulation of glucose metabolic process 4.2467E-4 7 29 2 6292
    regulation of cellular carbohydrate metabolic process 4.2467E-4 7 29 2 6292
    protein complex biogenesis 4.7723E-4 7 155 3 6292
    protein complex assembly 4.7723E-4 7 155 3 6292
    regulation of cellular process 5.3954E-4 7 796 5 6292
    gluconeogenesis 5.511E-4 7 33 2 6292
    cellular response to external stimulus 6.2038E-4 7 35 2 6292
    hexose biosynthetic process 6.2038E-4 7 35 2 6292
    cellular response to extracellular stimulus 6.2038E-4 7 35 2 6292
    cellular response to nutrient levels 6.2038E-4 7 35 2 6292
    regulation of biological process 6.3633E-4 7 824 5 6292
    regulation of carbohydrate metabolic process 6.5652E-4 7 36 2 6292
    monosaccharide biosynthetic process 7.3181E-4 7 38 2 6292
    response to extracellular stimulus 7.3181E-4 7 38 2 6292
    response to nutrient levels 7.3181E-4 7 38 2 6292
    response to external stimulus 7.3181E-4 7 38 2 6292
    cellular macromolecule metabolic process 8.282E-4 7 2285 7 6292
    pyruvate metabolic process 9.8164E-4 7 44 2 6292
    macromolecule metabolic process 1.0051E-3 7 2349 7 6292
    translesion synthesis 1.1125E-3 7 1 1 6292
    alcohol biosynthetic process 1.1199E-3 7 47 2 6292
    cell communication 1.2171E-3 7 49 2 6292
    alcohol metabolic process 1.3298E-3 7 220 3 6292
    cellular carbohydrate metabolic process 2.2054E-3 7 262 3 6292
    cellular response to nitrogen levels 2.224E-3 7 2 1 6292
    cellular response to nitrogen starvation 2.224E-3 7 2 1 6292
    macromolecular complex assembly 2.6978E-3 7 281 3 6292
    carbohydrate metabolic process 2.6978E-3 7 281 3 6292
    cellular response to stress 2.9533E-3 7 290 3 6292
    cellular carbohydrate biosynthetic process 3.0603E-3 7 78 2 6292
    DNA-dependent DNA replication 3.3772E-3 7 82 2 6292
    biological regulation 3.9225E-3 7 1213 5 6292
    carbohydrate biosynthetic process 4.1444E-3 7 91 2 6292
    developmental process 4.3093E-3 7 331 3 6292
    primary metabolic process 4.3588E-3 7 2896 7 6292
    macromolecular complex subunit organization 5.3413E-3 7 357 3 6292
    cellular response to glucose starvation 5.552E-3 7 5 1 6292
    cellular metabolic process 6.026E-3 7 3033 7 6292
    cellular response to stimulus 6.3249E-3 7 379 3 6292
    cellular component assembly 6.6113E-3 7 385 3 6292
    biofilm formation 6.6592E-3 7 6 1 6292
    positive regulation of biosynthetic process 7.231E-3 7 121 2 6292
    positive regulation of cellular biosynthetic process 7.231E-3 7 121 2 6292
    DNA replication 7.465E-3 7 123 2 6292
    metabolic process 7.9792E-3 7 3157 7 6292
    positive regulation of metabolic process 8.188E-3 7 129 2 6292
    positive regulation of cellular metabolic process 8.188E-3 7 129 2 6292
    monocarboxylic acid metabolic process 8.814E-3 7 134 2 6292
    positive regulation of cellular process 9.0704E-3 7 136 2 6292
    positive regulation of biological process 9.1999E-3 7 137 2 6292
    mutagenesis 9.9746E-3 7 9 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    AMP-activated protein kinase activity 1.5353E-15 7 6 5 6292
    protein kinase activity 1.4485E-9 7 156 6 6292
    transferase activity, transferring phosphorus-containing groups 5.6344E-9 7 420 7 6292
    phosphotransferase activity, alcohol group as acceptor 6.147E-9 7 198 6 6292
    protein serine/threonine kinase activity 1.1633E-8 7 91 5 6292
    kinase activity 1.2273E-8 7 222 6 6292
    transferase activity 5.1128E-7 7 797 7 6292
    catalytic activity 5.4045E-4 7 2150 7 6292
    protein serine/threonine kinase activator activity 2.224E-3 7 2 1 6292
    protein kinase activator activity 9.9746E-3 7 9 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle