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View Protein Complex Details

Complex Overview

From Publication: Krogan N. J. et al. (2006) Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature. 2006 Mar 30;440(7084):637-43. Epub 2006 Mar 22.
Notes: From the published set of core protein complex predictions.
Complex Size: 9 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
CMD1
  • incipient cellular bud site
  • cellular bud tip
  • central plaque of spindle pole body
  • cytoplasm
  • cellular bud neck
  • mating projection tip
  • cytoskeleton organization
  • cell budding
  • vacuole fusion, non-autophagic
  • mitosis
  • endocytosis
  • protein binding
  • calcium ion binding
  • calcium-dependent protein binding
  • CMK1
  • cytoplasm
  • signal transduction
  • protein amino acid phosphorylation
  • adenosine deaminase activity
  • CMK2
  • cytoplasm
  • signal transduction
  • protein amino acid phosphorylation
  • adenosine deaminase activity
  • CMP2
  • calcineurin complex
  • cytoplasm
  • adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion
  • cellular ion homeostasis
  • calcium-dependent protein serine/threonine phosphatase activity
  • CNA1
  • calcineurin complex
  • cytoplasm
  • cellular cell wall organization
  • adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion
  • cellular ion homeostasis
  • calcium-dependent protein serine/threonine phosphatase activity
  • CNB1
  • calcineurin complex
  • cytoplasm
  • cellular cell wall organization
  • adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion
  • cellular ion homeostasis
  • calcium-dependent protein serine/threonine phosphatase activity
  • calcium ion binding
  • MYO3
  • actin cortical patch
  • bipolar cellular bud site selection
  • response to osmotic stress
  • cellular cell wall organization
  • endocytosis
  • exocytosis
  • microfilament motor activity
  • MYO5
  • actin cortical patch
  • response to salt stress
  • bipolar cellular bud site selection
  • response to osmotic stress
  • cellular cell wall organization
  • endocytosis
  • exocytosis
  • microfilament motor activity
  • YGL242C
  • cellular_component
  • biological_process
  • molecular_function
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    calcineurin complex 8.0913E-9 9 4 3 6292
    protein serine/threonine phosphatase complex 1.3628E-6 9 17 3 6292
    actin cortical patch 1.449E-3 9 41 2 6292
    cortical actin cytoskeleton 2.324E-3 9 52 2 6292
    cortical cytoskeleton 2.324E-3 9 52 2 6292
    cytoskeletal part 2.3397E-3 9 201 3 6292
    cytoskeleton 2.8751E-3 9 216 3 6292
    actin cytoskeleton 6.1054E-3 9 85 2 6292
    central plaque of spindle pole body 7.1338E-3 9 5 1 6292
    cell cortex part 7.7349E-3 9 96 2 6292
    cell cortex 9.888E-3 9 109 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    adaptation of signaling pathway 7.3106E-7 9 14 3 6292
    adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion 7.3106E-7 9 14 3 6292
    reproduction 1.4106E-6 9 328 6 6292
    regulation of signaling pathway 6.5138E-6 9 28 3 6292
    signaling 1.094E-5 9 252 5 6292
    cell wall organization 6.2449E-5 9 173 4 6292
    external encapsulating structure organization 6.2449E-5 9 173 4 6292
    cellular cell wall organization 6.2449E-5 9 173 4 6292
    cell wall organization or biogenesis 1.2832E-4 9 208 4 6292
    cellular cell wall organization or biogenesis 1.2832E-4 9 208 4 6292
    response to pheromone involved in conjugation with cellular fusion 1.3504E-4 9 76 3 6292
    endocytosis 2.0898E-4 9 88 3 6292
    cell budding 2.2341E-4 9 90 3 6292
    asexual reproduction 2.2341E-4 9 90 3 6292
    membrane invagination 2.5417E-4 9 94 3 6292
    response to pheromone 2.7897E-4 9 97 3 6292
    cellular response to chemical stimulus 3.7285E-4 9 107 3 6292
    cellular chemical homeostasis 5.0993E-4 9 119 3 6292
    cellular ion homeostasis 5.0993E-4 9 119 3 6292
    cellular homeostasis 5.2263E-4 9 120 3 6292
    chemical homeostasis 5.6194E-4 9 123 3 6292
    ion homeostasis 5.6194E-4 9 123 3 6292
    conjugation with cellular fusion 5.8918E-4 9 125 3 6292
    conjugation 6.0312E-4 9 126 3 6292
    response to organic substance 7.7062E-4 9 137 3 6292
    multi-organism process 8.7338E-4 9 143 3 6292
    cell division 9.0949E-4 9 145 3 6292
    bipolar cellular bud site selection 9.9648E-4 9 34 2 6292
    signaling pathway 1.8147E-3 9 184 3 6292
    exocytosis 1.8221E-3 9 46 2 6292
    response to stimulus 2.1816E-3 9 766 5 6292
    cellular membrane organization 2.2409E-3 9 198 3 6292
    membrane organization 2.2409E-3 9 198 3 6292
    secretion 2.5043E-3 9 54 2 6292
    secretion by cell 2.5043E-3 9 54 2 6292
    reproduction of a single-celled organism 2.9133E-3 9 217 3 6292
    regulation of biological process 3.0404E-3 9 824 5 6292
    sexual reproduction 3.568E-3 9 233 3 6292
    cellular bud site selection 4.6571E-3 9 74 2 6292
    cytokinesis, site selection 4.6571E-3 9 74 2 6292
    response to osmotic stress 5.0339E-3 9 77 2 6292
    cell cycle cytokinesis 5.4243E-3 9 80 2 6292
    establishment of cell polarity 5.9661E-3 9 84 2 6292
    establishment or maintenance of cell polarity 6.1054E-3 9 85 2 6292
    cytokinetic process 7.1217E-3 9 92 2 6292
    protein amino acid phosphorylation 8.8641E-3 9 103 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    calcium-dependent protein serine/threonine phosphatase activity 2.0243E-9 9 3 3 6292
    protein serine/threonine phosphatase activity 5.1771E-6 9 26 3 6292
    microfilament motor activity 1.8149E-5 9 5 2 6292
    phosphoprotein phosphatase activity 2.4275E-5 9 43 3 6292
    adenosine deaminase activity 2.7204E-5 9 6 2 6292
    hydrolase activity 3.5985E-5 9 911 7 6292
    calcium ion binding 3.8057E-5 9 7 2 6292
    deaminase activity 1.6406E-4 9 14 2 6292
    phosphatase activity 2.02E-4 9 87 3 6292
    motor activity 2.7502E-4 9 18 2 6292
    phosphoric ester hydrolase activity 3.237E-4 9 102 3 6292
    hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 4.5308E-4 9 23 2 6292
    calcium-dependent protein binding 1.4304E-3 9 1 1 6292
    metal ion binding 2.5969E-3 9 55 2 6292
    ion binding 2.6911E-3 9 56 2 6292
    cation binding 2.6911E-3 9 56 2 6292
    hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 5.4243E-3 9 80 2 6292
    catalytic activity 9.6054E-3 9 2150 7 6292

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